4-Methylumbelliferyl-beta-D-glucopyranoside
- Product Name
- 4-Methylumbelliferyl-beta-D-glucopyranoside
- CAS No.
- 18997-57-4
- Chemical Name
- 4-Methylumbelliferyl-beta-D-glucopyranoside
- Synonyms
- MUD;MUG;MU-Glu;MUGGAL;MU-GAL;7-(B2;4-MU-GLU;GLC1-B-4MU;MUGLUCOSIDE;4-MU-β-Gluc
- CBNumber
- CB8853266
- Molecular Formula
- C16H18O8
- Formula Weight
- 338.31
- MOL File
- 18997-57-4.mol
4-Methylumbelliferyl-beta-D-glucopyranoside Property
- Melting point:
- 258-263 °C (dec.)
- Boiling point:
- 394.46°C (rough estimate)
- Density
- 1.522
- refractive index
- 1.4430 (estimate)
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- DMF: 5 mg/ml; DMSO: 50 mg/ml
- pka
- 12.73±0.70(Predicted)
- form
- Powder
- color
- White to off-white
- Water Solubility
- Soluble in DMF or water
- λmax
- 320nm(Buffer)(lit.)
- BRN
- 94672
- CAS DataBase Reference
- 18997-57-4(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M3633
- Product name
- 4-Methylumbelliferyl β-D-glucopyranoside
- Purity
- β-glucosidase substrate
- Packaging
- 1g
- Price
- $485
- Updated
- 2024/03/01
- Product number
- M3633
- Product name
- 4-Methylumbelliferyl β-D-glucopyranoside
- Purity
- β-glucosidase substrate
- Packaging
- 5g
- Price
- $1870
- Updated
- 2024/03/01
- Product number
- M3022
- Product name
- 4-Methylumbelliferyl β-D-Glucopyranoside
- Purity
- >98.0%(HPLC)
- Packaging
- 250mg
- Price
- $26
- Updated
- 2024/03/01
- Product number
- M3022
- Product name
- 4-Methylumbelliferyl β-D-Glucopyranoside
- Purity
- >98.0%(HPLC)
- Packaging
- 1g
- Price
- $73
- Updated
- 2024/03/01
- Product number
- J66630
- Product name
- 4-Methylumbelliferyl beta-D-glucopyranoside, 99%
- Packaging
- 1g
- Price
- $135
- Updated
- 2024/03/01
4-Methylumbelliferyl-beta-D-glucopyranoside Chemical Properties,Usage,Production
Description
4-Methylumbelliferyl-β-D-Glucopyranoside (4-MUG) is a fluorogenic substrate of β-glucosidase and β-glucocerebrosidase (also known as glucosylceramidase). In addition to its use in characterizing novel β-glucosidases, 4-MUG is used in assays to evaluate deficiency in β- glucocerebrosidase activity related to Gaucher disease. Hydrolysis of 4-MUG releases the fluorescent product 4-MU, which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively.
Chemical Properties
White Powder
Uses
A fluorogenic substrate in the assay of ?-glucosidase. Fluorescence: max. Abs. 316nm; max. Em. 372nm; e x 10-3: 15
Uses
A fluorogenic substrate in the assay of ?-glucosidase.Fluorescence: max. Abs. 316nm; max. Em. 372nm; e x 10-3: 15
Uses
4-Methylumbelliferyl β-D-glucopyranoside has been used as substrate:
- in glucosylceramidase β enzyme activity assay in lysosome-enriched fractions from primary hippocampal neurons
- in β-glucosidase assay during yeast fermentation
- to assay glucocerebrosidase 1 (GBA1)-related glucosidase activity in macrophage cell line (RAW)
Definition
ChEBI: A beta-D-glucoside having a 4-methylumbelliferyl substituent at the anomeric position.
Biochem/physiol Actions
4-Methylumbelliferyl β-D-glucopyranoside is a synthetic enzymatic substrate for glycosidase. It has been used as substrate for the β- glucosidase from enterococci.
Purification Methods
4-Methylumbellifer-7-yl--Dglucopyranoside crystallises as the half hydrate from hot H2O. [Constantzas & Kocourek Collect Czech Chem Commun 24 1099 1959, De Re et al. Ann Chim (Rome) 4 9 2089 1959, Courtin-Duchateau & Veyrière Carbohydr Research 65 23, 29 1978, Beilstein 18 III/IV 5152, 8 IV 433, 18/7 V 616.]
4-Methylumbelliferyl-beta-D-glucopyranoside Preparation Products And Raw materials
Raw materials
Preparation Products
4-Methylumbelliferyl-beta-D-glucopyranoside Suppliers
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View Lastest Price from 4-Methylumbelliferyl-beta-D-glucopyranoside manufacturers
- Product
- 4-Methylumbelliferyl-beta-D-glucopyranoside 18997-57-4
- Price
- US $0.00/G
- Min. Order
- 10G
- Purity
- 98%min
- Supply Ability
- 30kg/month
- Release date
- 2023-02-15
- Product
- 4-Methylumbelliferyl-beta-D-glucopyranoside 18997-57-4
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-27
- Product
- 4-Methylumbelliferyl-beta-D-glucopyranoside 18997-57-4
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2018-12-18