2,5-Dichlorophenol Property

Melting point:

54-57 °C (lit.)

Boiling point:

211 °C (lit.)

Density 

1.3446 (rough estimate)

refractive index 

1.4430 (estimate)

Flash point:

100 °C

storage temp. 

0-6°C

solubility 

2000mg/l (experimental)

form 

Crystals

pka

7.53±0.10(Predicted)

color 

White to light brown

Water Solubility 

3 g/L (20 ºC)

BRN 

1907692

LogP

3.06 at 20℃

CAS DataBase Reference

583-78-8(CAS DataBase Reference)

NIST Chemistry Reference

Phenol, 2,5-dichloro-(583-78-8)

EPA Substance Registry System

2,5-Dichlorophenol (583-78-8)

Safety

Hazard Codes 

C,N,Xn

Risk Statements 

22-34-51/53-36/38

Safety Statements 

26-36/37/39-45-61-37/39

RIDADR 

UN 2020 6.1/PG 3

WGK Germany 

2

RTECS 

SK8600000

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

III

HS Code 

29081000

Hazardous Substances Data

583-78-8(Hazardous Substances Data)

Toxicity

LD50 orally in Rabbit: 580 mg/kg

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

2,5-Dichlorophenol Chemical Properties,Usage,Production

Chemical Properties

white to light brown crystals

Uses

2,5-Dichlorophenol may be used as an analytical reference standard for the determination of the analyte in water, and wood, paper, cardboard, fruits, and fruit juices using simultaneous dispersive liquid-liquid microextraction and derivatization followed by gas chromatography-electron-capture detection (GC-ECD) and gas chromatography-mass spectrometry (GC-MS), respectively.

Uses

2,5-Dichlorophenol is an intermediates in the manufacture of more complex chemical compounds such as fungicides.

Definition

ChEBI: A dichlorophenol with the chloro substituents at positions 2 and 5.

Synthesis Reference(s)

Journal of the American Chemical Society, 74, p. 3890, 1952 DOI: 10.1021/ja01135a052

General Description

Prisms (from benzene, petroleum ether) or white crystals. Odor threshold 30 μg/L at 68-72°F; 33 μg/L at 86°F. Taste threshold 0.5 μg/L.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

2,5-Dichlorophenol is incompatible with acid chlorides, acid anhydrides and oxidizing agents.

Fire Hazard

Flash point data for 2,5-Dichlorophenol are not available. 2,5-Dichlorophenol is probably combustible.

Purification Methods

Crystallise it from ligroin and sublime it in a vacuum or distil it. [Beilstein 6 IV 942.]