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lucanthone

Product Name
lucanthone
CAS No.
479-50-5
Chemical Name
lucanthone
Synonyms
Lucantona;lucanthone;Lycanthone;Lucanthonum;Lucanthone, 10 mM in DMSO;Autophagy,inhibit,Lucanthone,Inhibitor;1-(2-diethylaminoethylamino)-4-(methyl)thioxanthen-9-one;1-[[2-(Diethylamino)ethyl]amino]-4-methyl-9H-thioxanthen-9-one;9H-Thioxanthen-9-one, 1-[[2-(diethylamino)ethyl]amino]-4-methyl-
CBNumber
CB8875332
Molecular Formula
C20H24N2OS
Formula Weight
340.48
MOL File
479-50-5.mol
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lucanthone Property

Melting point:
64.5°C
Boiling point:
512.4±50.0 °C(Predicted)
Density 
1.0915 (rough estimate)
refractive index 
1.5950 (estimate)
storage temp. 
Store at -20°C
solubility 
DMSO : 25 mg/mL (73.43 mM)
form 
Solid
pka
10.00±0.25(Predicted)
color 
Off-white to orange
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0005244
Product name
LUCANTHONE
Purity
95.00%
Packaging
5MG
Price
$498.16
Updated
2021/12/16
Ambeed
Product number
A737309
Product name
1-((2-(Diethylamino)ethyl)amino)-4-methyl-9H-thioxanthen-9-one
Purity
99+%
Packaging
25mg
Price
$130
Updated
2021/12/16
Ambeed
Product number
A737309
Product name
1-((2-(Diethylamino)ethyl)amino)-4-methyl-9H-thioxanthen-9-one
Purity
99+%
Packaging
50mg
Price
$195
Updated
2021/12/16
Ambeed
Product number
A737309
Product name
1-((2-(Diethylamino)ethyl)amino)-4-methyl-9H-thioxanthen-9-one
Purity
99+%
Packaging
100mg
Price
$285
Updated
2021/12/16
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lucanthone Chemical Properties,Usage,Production

Definition

ChEBI: Lucanthone is a thioxanthen-9-one compound having a methyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. Formerly used for the treatment of schistosomiasis. It is a prodrug, being metabolised to hycanthone. It has a role as a schistosomicide drug, an antineoplastic agent, a photosensitizing agent, an EC 5.99.1.2 (DNA topoisomerase) inhibitor, an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor, a prodrug, an adjuvant and a mutagen.

Safety Profile

Poison by intravenous route. Human mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and SOx.

lucanthone Preparation Products And Raw materials

Raw materials

Preparation Products

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479-50-5, lucanthoneRelated Search:


  • lucanthone
  • 1-[[2-(Diethylamino)ethyl]amino]-4-methyl-9H-thioxanthen-9-one
  • Lycanthone
  • 1-(2-diethylaminoethylamino)-4-(methyl)thioxanthen-9-one
  • Lucanthonum
  • Lucantona
  • 9H-Thioxanthen-9-one, 1-[[2-(diethylamino)ethyl]amino]-4-methyl-
  • Autophagy,inhibit,Lucanthone,Inhibitor
  • Lucanthone, 10 mM in DMSO
  • 479-50-5