Hycanthone
- Product Name
- Hycanthone
- CAS No.
- 3105-97-3
- Chemical Name
- Hycanthone
- Synonyms
- ETRENOL;hycanthon;nsc-134434;Win 249-33;HYCANTHONE;Etrenol(mesylate);lucanthonemetabolite;1-(2-diethylaminoethylamino)-4-methylol-thioxanthen-9-one;1-((2-(diethylamino)ethyl)amino)-4-(hydroxymethyl)thioxanthen-9-one;1-((2-(diethylamino)ethyl)amino)-4-(hydroxymethyl)-9h-thioxanthen-9-on
- CBNumber
- CB9181533
- Molecular Formula
- C20H24N2O2S
- Formula Weight
- 356.48
- MOL File
- 3105-97-3.mol
Hycanthone Property
- Melting point:
- 100.6-102.8°
- Boiling point:
- 570.5±50.0 °C(Predicted)
- Density
- 1.1269 (rough estimate)
- refractive index
- 1.6000 (estimate)
- storage temp.
- Keep in dark place,Sealed in dry,2-8°C
- solubility
- DMSO : 30 mg/mL (84.16 mM)
- pka
- pKa 3.40 (Uncertain)
- EPA Substance Registry System
- Hycanthone (3105-97-3)
Safety
- Hazard Codes
- T
- Risk Statements
- 45-46-20/21/22
- Safety Statements
- 53-36/37/39-45
- WGK Germany
- 3
- RTECS
- XO1590000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled
H350May cause cancer
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P322Specific measures (see …on this label).
P330Rinse mouth.
P363Wash contaminated clothing before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- H674305
- Product name
- Hycanthone
- Packaging
- 1mg
- Price
- $185
- Updated
- 2021/12/16
- Product number
- MTB0000500
- Product name
- HYCANTHONE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $505
- Updated
- 2021/12/16
- Product number
- orb573440
- Product name
- Hycanthone
- Purity
- >98%
- Packaging
- 100mg
- Price
- $765
- Updated
- 2021/12/16
- Product number
- orb573440
- Product name
- Hycanthone
- Purity
- >98%
- Packaging
- 250mg
- Price
- $1431.4
- Updated
- 2021/12/16
- Product number
- CS-4690
- Product name
- Hycanthone
- Purity
- 98.85%
- Packaging
- 10mg
- Price
- $60
- Updated
- 2021/12/16
Hycanthone Chemical Properties,Usage,Production
Uses
Antischistosomal.
Uses
Hycanthone is the active metabolite of the anthelmintic prodrug Lucanthone (L473700), which is used in the treatment of schistosomiasis.
Definition
ChEBI: A thioxanthen-9-one compound having a hydroxymethyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. It was formerly used (particularly as the monomethanesulfonic acid salt) as a schistosomicide for individual or mass treatement of infection with Schistosoma haematobium and S. mansoni, but due to its toxicity and concern about possible carcinogenicity, it has been replaced by other drugs such as praziquantel.
General Description
Odorless canary yellow to yellow-orange crystalline powder. Bitter taste.
Air & Water Reactions
1-[(2-[DIETHYLAMINO]ETHYL)AMINO]-4-[HYDROXYMETHYL]-9H-THIOXANTHEN-9-ONE may be sensitive to prolonged exposure to air and light. Highly soluble in water.
Reactivity Profile
1-[(2-[DIETHYLAMINO]ETHYL)AMINO]-4-[HYDROXYMETHYL]-9H-THIOXANTHEN-9-ONE is very sensitive to acid. .
Fire Hazard
Flash point data for 1-[(2-[DIETHYLAMINO]ETHYL)AMINO]-4-[HYDROXYMETHYL]-9H-THIOXANTHEN-9-ONE are not available; however, 1-[(2-[DIETHYLAMINO]ETHYL)AMINO]-4-[HYDROXYMETHYL]-9H-THIOXANTHEN-9-ONE is probably combustible.
Safety Profile
Poison by subcutaneous, intravenous, and intramuscular routes. Moderately toxic by ingestion. Experimental teratogenic effects. Human mutation data reported. Questionable carcinogen with experimental carcinogenic data. When heated to decomposition it emits very toxic fumes of NOx and SOx.
Hycanthone Preparation Products And Raw materials
Raw materials
Preparation Products
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