Hycanthone

Product Name: Hycanthone
CAS No.: 3105-97-3
Chemical Name: Hycanthone
Synonyms: ETRENOL;hycanthon;nsc-134434;Win 249-33;HYCANTHONE;Etrenol(mesylate);lucanthonemetabolite;1-(2-diethylaminoethylamino)-4-methylol-thioxanthen-9-one;1-((2-(diethylamino)ethyl)amino)-4-(hydroxymethyl)thioxanthen-9-one;1-((2-(diethylamino)ethyl)amino)-4-(hydroxymethyl)-9h-thioxanthen-9-on
CBNumber: CB9181533
Molecular Formula: C20H24N2O2S
Formula Weight: 356.48
MOL File: 3105-97-3.mol

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Hycanthone Property

Melting point:: 100.6-102.8°
Boiling point:: 570.5±50.0 °C(Predicted)
Density: 1.1269 (rough estimate)
refractive index: 1.6000 (estimate)
storage temp.: Keep in dark place,Sealed in dry,2-8°C
solubility: DMSO : 30 mg/mL (84.16 mM)
pka: pKa 3.40 (Uncertain)
EPA Substance Registry System: Hycanthone (3105-97-3)

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Safety

Hazard Codes: T
Risk Statements: 45-46-20/21/22
Safety Statements: 53-36/37/39-45
WGK Germany: 3
RTECS: XO1590000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

H350May cause cancer

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P322Specific measures (see …on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: H674305
Product name: Hycanthone
Packaging: 1mg
Price: $185
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: MTB0000500
Product name: HYCANTHONE
Purity: 95.00%
Packaging: 5MG
Price: $505
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb573440
Product name: Hycanthone
Purity: >98%
Packaging: 100mg
Price: $765
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb573440
Product name: Hycanthone
Purity: >98%
Packaging: 250mg
Price: $1431.4
Updated: 2021/12/16

ChemScene

Product number: CS-4690
Product name: Hycanthone
Purity: 98.85%
Packaging: 10mg
Price: $60
Updated: 2021/12/16

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Hycanthone Chemical Properties,Usage,Production

Uses

Antischistosomal.

Uses

Hycanthone is the active metabolite of the anthelmintic prodrug Lucanthone (L473700), which is used in the treatment of schistosomiasis.

Definition

ChEBI: A thioxanthen-9-one compound having a hydroxymethyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. It was formerly used (particularly as the monomethanesulfonic acid salt) as a schistosomicide for individual or mass treatement of infection with Schistosoma haematobium and S. mansoni, but due to its toxicity and concern about possible carcinogenicity, it has been replaced by other drugs such as praziquantel.

General Description

Odorless canary yellow to yellow-orange crystalline powder. Bitter taste.

Air & Water Reactions

1-[(2-[DIETHYLAMINO]ETHYL)AMINO]-4-[HYDROXYMETHYL]-9H-THIOXANTHEN-9-ONE may be sensitive to prolonged exposure to air and light. Highly soluble in water.

Reactivity Profile

1-[(2-[DIETHYLAMINO]ETHYL)AMINO]-4-[HYDROXYMETHYL]-9H-THIOXANTHEN-9-ONE is very sensitive to acid. .

Fire Hazard

Flash point data for 1-[(2-[DIETHYLAMINO]ETHYL)AMINO]-4-[HYDROXYMETHYL]-9H-THIOXANTHEN-9-ONE are not available; however, 1-[(2-[DIETHYLAMINO]ETHYL)AMINO]-4-[HYDROXYMETHYL]-9H-THIOXANTHEN-9-ONE is probably combustible.

Safety Profile

Poison by subcutaneous, intravenous, and intramuscular routes. Moderately toxic by ingestion. Experimental teratogenic effects. Human mutation data reported. Questionable carcinogen with experimental carcinogenic data. When heated to decomposition it emits very toxic fumes of NOx and SOx.

Hycanthone Preparation Products And Raw materials

Raw materials

Preparation Products

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Hycanthone Suppliers

China 30 India 1 Switzerland 1 United Kingdom 1 United States 7 Global 40

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3105-97-3, HycanthoneRelated Search:

Sofalcone Ceftezole Triethyl phosphate 1-[[2-(Diethylamino)ethyl]amino]-4-(hydroxymethyl)-9H-thioxanthen-9-one=2-furancarboxylate THIOXANTHENE (2-METHYLSULFANYL-PHENYL)-METHANOL Thioxanthen-9-one 2,6-DIMETHYLTHIOANISOLE Hycanthone lucanthone 2-amino-5-methylbenzophenone

1-[(2-[DIETHYLAMINO]ETHYL)AMINO]-4-[HYDROXYMETHYL]-9H-THIOXANTHEN-9-ONE

ETRENOL

Etrenol(mesylate)

Win 249-33

1-(2-diethylaminoethylamino)-4-methylol-thioxanthen-9-one

9H-Thioxanthen-9-one, 1-[[2-(diethylaMino)ethyl]aMino]-4-(hydroxyMethyl)-

1-((2-(diethylamino)ethyl)amino)-4-(hydroxymethyl)-9h-thioxanthen-9-on

1-((2-(diethylamino)ethyl)amino)-4-(hydroxymethyl)thioxanthen-9-one

hycanthon

lucanthonemetabolite

nsc-134434

HYCANTHONE

3105-97-3 1-[(2-[DIETHYLAMINO]ETHYL)AMINO]-4-[HYDROXYMETHYL]-9H-THIOXANTHEN-9-ONE

APE1,inhibit,Hycanthone,DNA/RNA Synthesis,acid,intercalator,Topoisomerase,Lucanthone,anti-schistosomal,nucleic,apurinic,endonuclease-1,biosynthesis,Inhibitor,thioxanthenone,Parasite

3105-97-3

HU - HZ

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