etomidoline
- Product Name
- etomidoline
- CAS No.
- 21590-92-1
- Chemical Name
- etomidoline
- Synonyms
- Nonspa;K 2680;Smedolin;Amidoline;etomidoline;Phthalimidine, 2-ethyl-3-(β-piperidino-p-phenetidino)- (8CI);2-Ethyl-2,3-dihydro-3-[4-(2-piperidinoethoxy)anilino]-1H-isoindol-1-one;2-Ethyl-2,3-dihydro-3-[[4-[2-(1-piperidinyl)ethoxy]phenyl]amino]-1H-isoindol-1-one;1H-Isoindol-1-one, 2-ethyl-2,3-dihydro-3-[[4-[2-(1-piperidinyl)ethoxy]phenyl]amino]-
- CBNumber
- CB8896360
- Molecular Formula
- C23H29N3O2
- Formula Weight
- 379.5
- MOL File
- 21590-92-1.mol
etomidoline Property
- Melting point:
- 106-107°
- Boiling point:
- 507.34°C (rough estimate)
- Density
- 1.1315 (rough estimate)
- refractive index
- 1.6500 (estimate)
- pka
- 8.75±0.10(Predicted)
Safety
- Toxicity
- LD50 in mice (mg/kg): 176 orally; 44.8 i.v. (Giraldi, Mariotti, 1971)
N-Bromosuccinimide Price
- Product number
- API0011397
- Product name
- ETOMIDOLINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $499.42
- Updated
- 2021/12/16
etomidoline Chemical Properties,Usage,Production
Originator
Smedolin,Yamanouchi,Japan,1976
Definition
ChEBI: Etomidoline is an organic molecular entity.
Manufacturing Process
31.3 g of 1-oxo-3-(aminophenyl-p-ethoxypiperidino)-isoindoline (0.0892 mol)
are dissolved in 500 ml of anhydrous N,N-dimethylformamide. To this solution
5.75 g of NaH (0.105 mol) and 7.24 ml of CH2CH2I (0.0945 mol) are added
and the resulted mixture is heated at 70°C for 1 hour, and then poured into
an excess of water. 1-oxo-2-ethyl-3-(aminophenyl-p-ethoxypiperidino)-
isoindoline (MP 106°C to 107°C) is obtained by crystallization with ligroin.
1-oxo-2-ethyl-3-(iminophenyl-p-ethoxypiperidino)-isoindoline (MP 103°C to
104°C) is obtained as a byproduct with the above compound. This latter
compound was reduced to produce 1-oxo-2-ethyl-3-(aminophenyl-p-ethoxypiperidino)-isoindoline.
Therapeutic Function
Muscle relaxant
etomidoline Preparation Products And Raw materials
Raw materials
Preparation Products
etomidoline Suppliers
- Tel
- +8613564774135
- zijue.cai@tsbiochem.com
- Country
- United States
- ProdList
- 19885
- Advantage
- 58
- Tel
- support@targetmol.com
- Country
- United States
- ProdList
- 38632
- Advantage
- 58