Phosphinothricin
- Product Name
- Phosphinothricin
- CAS No.
- 51276-47-2
- Chemical Name
- Phosphinothricin
- Synonyms
- C05042;HOE-866;HOE-35956;Glufosite;Phosphinothricin;2'-Anhydrouridine;13C,2H3]-Glufosinate;IAJOBQBIJHVGMQ-UHFFFAOYSA-N;Phosphinothricin ammonium salt;2-amino-4-(hydroxymethylphosphinyl)butyric acid
- CBNumber
- CB8918965
- Molecular Formula
- C5H12NO4P
- Formula Weight
- 181.13
- MOL File
- 51276-47-2.mol
Phosphinothricin Property
- Melting point:
- 229-231° (dec)
- Boiling point:
- 519.1±45.0 °C(Predicted)
- Density
- 1.378±0.06 g/cm3(Predicted)
- solubility
- Aqueous Acid (Slightly), Methanol (Very Slightly, Sonicated), Water (Slightly)
- pka
- 2.22±0.10(Predicted)
- form
- Solid
- color
- White to Light Beige
- Stability:
- Hygroscopic
- LogP
- -0.750 (est)
- EPA Substance Registry System
- Butanoic acid, 2-amino-4-(hydroxymethylphosphinyl)- (51276-47-2)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H360May damage fertility or the unborn child
H373May cause damage to organs through prolonged or repeated exposure
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P314Get medical advice/attention if you feel unwell.
P322Specific measures (see …on this label).
P330Rinse mouth.
P363Wash contaminated clothing before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- G596958
- Product name
- Glufosinate
- Packaging
- 1mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- 286625
- Product name
- Phosphinothricin
- Packaging
- 50mg
- Price
- $389
- Updated
- 2021/12/16
- Product number
- AGR0000264
- Product name
- DL-PHOSPHINOTRICIN
- Purity
- 95.00%
- Packaging
- 250MG
- Price
- $470
- Updated
- 2021/12/16
- Product number
- AGR0000264
- Product name
- DL-PHOSPHINOTRICIN
- Purity
- 95.00%
- Packaging
- 100MG
- Price
- $498
- Updated
- 2021/12/16
- Product number
- J52992
- Product name
- Glufosinate
- Packaging
- 250mg
- Price
- $250
- Updated
- 2021/12/16
Phosphinothricin Chemical Properties,Usage,Production
Definition
ChEBI: 2-amino-4-[hydroxy(methyl)phosphoryl]butanoic acid is a non-proteinogenic alpha-amino acid that is 2-aminobutanoic acid which is substituted at position 4 by a hydroxy(methyl)phosphoryl group. It is a member of phosphinic acids and a non-proteinogenic alpha-amino acid.
Enzyme inhibitor
This dephospho transition-state analogue (FW = 177.10 g/mol; CAS 51276- 47-2) is naturally occurring glutamate analogue, first isolated from Streptomyces viridochromogenes. Phosphonothricin is a slow, tight-binding inhibitor of glutamine synthetase that binds at the glutamate binding site and stabilizes the flap of a glutamyl residue in a position blocking glutamate entry into the active site, thereby trapping the inhibitor on the enzyme. Phosphinothricin undergoes an ATP-dependent phosphorylation. Note: Phosphinothricin is a component of the antibiotics bialaphos and phosalacine. The monoammonium salt of the racemic compound, also called glufosinate-ammonium, is a post-emergent herbicide.
Metabolic pathway
When 14C-phosphinothricin [homoalanin-4-yl- (methyl)phosphinic acid] is incubated in the cell suspension cultures of soybean, wheat, and maize, in maize cells which take up to 50% of the applied radioactivity, four different metabolites are detected which are identified as 4-methylphosphinico-2-oxo- butyric acid, 4-methylphosphinico-2-hydroxybutyric acid, 4-methylphosphinicobutyric acid, and 3- methylphosphinicopropionic acid. In soybean and wheat cultures, 10 and 6% of the applied radioactivity is taken up, respectively. In soybean, only one metabolite, 3-methylphosphinicopropionic acid, is detected, whereas in wheat, 4-methyl- phosphinicobutyric acid is additionally present.
Phosphinothricin Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Phosphinothricin manufacturers
- Product
- Phosphinothricin 51276-47-2
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99.99%
- Supply Ability
- 50000tons
- Release date
- 2023-08-08
- Product
- Glufosinate 51276-47-2
- Price
- US $0.00/Kg/Bag
- Min. Order
- 10Kg/Bag
- Purity
- 99%
- Supply Ability
- 20 Tons
- Release date
- 2020-10-29