Thieno[2,3-c]pyridine-2-carboxylic acid (9CI)
- Product Name
- Thieno[2,3-c]pyridine-2-carboxylic acid (9CI)
- CAS No.
- 478149-00-7
- Chemical Name
- Thieno[2,3-c]pyridine-2-carboxylic acid (9CI)
- Synonyms
- thieno[2,3-c]pyridine-2-carboxylic acid;Thieno[2,3-c]pyridine-2-carboxylic acid (9CI)
- CBNumber
- CB91045272
- Molecular Formula
- C8H5NO2S
- Formula Weight
- 179.2
- MOL File
- 478149-00-7.mol
Thieno[2,3-c]pyridine-2-carboxylic acid (9CI) Property
- Boiling point:
- 418.3±25.0 °C(Predicted)
- Density
- 1.508±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- pka
- 2.31±0.30(Predicted)
- Appearance
- Light brown to brown Solid
Safety
- HS Code
- 2934999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- T344563
- Product name
- Thieno[2,3-c]pyridine-2-carboxylicAcid
- Packaging
- 10mg
- Price
- $40
- Updated
- 2021/12/16
- Product number
- G14637
- Product name
- Thieno[2,3-c]pyridine-2-carboxylicacid
- Packaging
- 500mg
- Price
- $160
- Updated
- 2021/12/16
- Product number
- OR918586
- Product name
- Thieno[2,3-c]pyridine-2-carboxylicacid
- Purity
- 96%
- Packaging
- 250mg
- Price
- $210
- Updated
- 2021/12/16
- Product number
- G14637
- Product name
- Thieno[2,3-c]pyridine-2-carboxylicacid
- Packaging
- 1g
- Price
- $240
- Updated
- 2021/12/16
- Product number
- 189389
- Product name
- Thieno[2,3-c]pyridine-2-carboxylic acid
- Packaging
- 500mg
- Price
- $450
- Updated
- 2021/12/16
Thieno[2,3-c]pyridine-2-carboxylic acid (9CI) Chemical Properties,Usage,Production
Uses
Thieno[2,3-c]pyridine-2-carboxylic Acid is used in the preparation of inhibitors such as BET bromodomain inhibitors.
Synthesis
478148-99-1
478149-00-7
Ethyl thieno[2,3-c]pyridine-2-carboxylate (C121, 577 mg, 2.99 mmol) was added to a solvent mixture of methanol (15 mL) and water (1.5 mL) with 2 M sodium hydroxide solution (1.5 mL, 3.0 mmol). The reaction mixture was stirred at room temperature for 24 hours. Upon completion of the reaction, the solvent was removed by vacuum concentration and the residue was dissolved in water (75 mL). The solution was acidified to pH 3 with concentrated hydrochloric acid to form a slurry. The solid product was collected by filtration, washed sequentially with water and ether, and dried to give thieno[2,3-c]pyridine-2-carboxylic acid (C122) as an off-white solid in 38% yield. High-resolution mass spectrometry (FAB) analysis showed that the calculated value of C8H5NO2S + H was 180.0119 and the measured value was 180.0119 (M + H)+.
References
[1] Patent: US2003/45540, 2003, A1
Thieno[2,3-c]pyridine-2-carboxylic acid (9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
Thieno[2,3-c]pyridine-2-carboxylic acid (9CI) Suppliers
- Tel
- --
- Fax
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- sales@ajchem.in
- Country
- India
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- Advantage
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View Lastest Price from Thieno[2,3-c]pyridine-2-carboxylic acid (9CI) manufacturers
- Product
- Thieno[2,3-c]pyridine-2-carboxylic acid (9CI) 478149-00-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 100kg
- Release date
- 2020-01-14