ChemicalBook > CAS DataBase List > ABAGOVOMAB
ABAGOVOMAB
- Product Name
- ABAGOVOMAB
- CAS No.
- 792921-10-9
- Chemical Name
- ABAGOVOMAB
- Synonyms
- ACA 125;ABAGOVOMAB;Research Grade Abagovomab;Research Grade Abagovomab(DHJ31001);Immunoglobulin G1, anti-(mouse oc 125) (mouse monoclonal aca-125 clone 3D5 gamma-chain), disulfide with mouse monoclonal aca-125 clone 3D5 kappa-chain, dimer
- CBNumber
- CB91091860
- Formula Weight
- 0
- MOL File
- Mol file
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ABAGOVOMAB Property
- form
- Liquid
- color
- Colorless to light yellow
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ABAGOVOMAB Chemical Properties,Usage,Production
Uses
Abagovomab (Anti-Human CA-125 Recombinant Antibody) is a murine monoclonal anti-idiotypic antibody, against the tumor-associated antigen, CA-125. Abagovomab is generated by a mouse hybridoma, can imitate the human TAA, CA-125. Abagovomab can elicit humoral and cellular immune responses against ovarian cancer (oc)[1][2].
References
[1] Pfisterer J, et al. The anti-idiotypic antibody abagovomab in patients with recurrent ovarian cancer. A phase I trial of the AGO-OVAR. Ann Oncol. 2006 Oct;17(10):1568-77. DOI:10.1093/annonc/mdl357
[2] Grisham RN, et al. Abagovomab: an anti-idiotypic CA-125 targeted immunotherapeutic agent for ovarian cancer. Immunotherapy. 2011 Feb;3(2):153-62. DOI:10.2217/imt.10.100
ABAGOVOMAB Preparation Products And Raw materials
Raw materials
Preparation Products
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