ChemicalBook > CAS DataBase List > S-Trityl-D-cysteine

S-Trityl-D-cysteine

Product Name: S-Trityl-D-cysteine
CAS No.: 25840-82-8
Chemical Name: S-Trityl-D-cysteine
Synonyms: D-Cys(Trt)-OH;S-Trityl-D-cysteine99%;(-)-S-Trityl-D-cysteine;(-)-S-Trityl-D-cysteine,98%;(-)-S-Trityl-D-cysteine,97%;S-Trityl-D-cysteine USP/EP/BP;S-(Triphenylmethyl)-D-cysteine;D-Cysteine, S-(triphenylmethyl)-;(S)-2-AMino-3-(tritylthio)propanoic acid;(2S)-2-amino-3-tritylsulfanylpropanoicaci
CBNumber: CB91117670
Molecular Formula: C22H21NO2S
Formula Weight: 363.47
MOL File: 25840-82-8.mol

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S-Trityl-D-cysteine Property

Boiling point:: 524.7±50.0 °C(Predicted)
Density: 1.232±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka: 2.22±0.10(Predicted)
form: Solid
color: White to off-white
optical activity: Consistent with structure
Water Solubility: Sparingly soluble in water 0.022 g/L 25°C.

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Safety

Risk Statements: 22
Safety Statements: 22-24/25

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Usbiological

Product number: 241749
Product name: S-Trityl-D-cysteine 99+%
Packaging: 1g
Price: $186
Updated: 2021/12/16

TRC

Product number: T887925
Product name: (-)-S-Trityl-D-cysteine
Packaging: 500mg
Price: $65
Updated: 2021/12/16

TRC

Product number: T887925
Product name: (-)-S-Trityl-D-cysteine
Packaging: 100mg
Price: $45
Updated: 2021/12/16

Chem-Impex

Product number: 05952
Product name: -Trityl-D-cysteine
Purity: ≥ 98% (HPLC)
Packaging: 25G
Price: $45
Updated: 2021/12/16

Activate Scientific

Product number: AS112876
Product name: H-D-Cys(Trt)-OH
Purity: 97%
Packaging: 5G
Price: $34
Updated: 2021/12/16

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S-Trityl-D-cysteine Chemical Properties,Usage,Production

Uses

(-)-S-Trityl-D-cysteine is used in medicine as intermediate. It inhibits the human mitotic kinesin Eg5.

Synthesis

76-84-6

921-01-7

2799-07-7

General procedure for the synthesis of S-triphenylmethyl-L-cysteine from triphenylmethanol and D-cysteine: D-cysteine (242.30 mg, 2.0 mmol) was placed in a single-necked flask, trifluoroacetic acid (TFA, 4 mL) was added and stirred at room temperature. Triphenylmethanol (520.68 mg, 2.0 mmol) was then added and the reaction continued to be stirred at room temperature for 2 hours. After completion of the reaction, the reaction mixture was cooled to 0 °C, anhydrous ether (30 mL) was added, and the pH was adjusted to 4-5 by slowly adding 4 N NaOH aqueous solution dropwise with stirring.Next, 10% saturated sodium acetate aqueous solution was added, and stirring was continued for 1 h to stabilize the pH at 5-6.The reaction mixture was filtered, and the filter cake was washed with anhydrous ether (30 mL × 2) to afford the white powdery product S Triphenylmethyl-L-cysteine (566.4 mg, yield: 77.90%).

References

[1] Patent: CN106432014, 2017, A. Location in patent: Paragraph 0199; 0200; 0201; 0202

S-Trityl-D-cysteine Preparation Products And Raw materials

Raw materials

Preparation Products

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25840-82-8, S-Trityl-D-cysteineRelated Search:

H-D-Cys(Trt)-OtBu·HCl H-D-Cys(Trt)-NH2 H-D-Cys(Acm)-OMe·HCl H-D-CYS(ACM)-OH HCL 4-METHOXY-TRITYL-D-CYSTEINE FMOC-D-PEN(TRT)-OH N-Fmoc-S-trityl-D-cysteine S-Trityl-D-cysteine Fmoc-D-Cys(Trt)- OPfp FMOC-D-CYS(MMT)-OH N-Boc-S-Trityl-L-cysteine BOC-D-PEN(TRT)-OH H-D-PEN(TRT)-OH

S-(Triphenylmethyl)-D-cysteine

2-amino-3-[tri(phenyl)methylsulfanyl]propanoic acid

2-amino-3-[tri(phenyl)methylthio]propionic acid

2-azanyl-3-[tri(phenyl)methylsulfanyl]propanoic acid

(S)-2-AMino-3-(tritylthio)propanoic acid

D-Cys(Trt)-OH

S-Trityl-D-cysteine99%

(2S)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoic acid

D-Cysteine, S-(triphenylmethyl)-

(-)-S-Trityl-D-cysteine,98%

(-)-S-Trityl-D-cysteine

(2S)-2-amino-3-tritylsulfanylpropanoicaci

S-Trityl-D-cysteine USP/EP/BP

(2S)-2-amino-3-tritylsulfanylpropanoic acid

(-)-S-Trityl-D-cysteine,97%

25840-82-8

C22H21NO2S