S-Trityl-D-cysteine
- Product Name
- S-Trityl-D-cysteine
- CAS No.
- 25840-82-8
- Chemical Name
- S-Trityl-D-cysteine
- Synonyms
- D-Cys(Trt)-OH;S-Trityl-D-cysteine99%;(-)-S-Trityl-D-cysteine;(-)-S-Trityl-D-cysteine,98%;(-)-S-Trityl-D-cysteine,97%;S-Trityl-D-cysteine USP/EP/BP;S-(Triphenylmethyl)-D-cysteine;D-Cysteine, S-(triphenylmethyl)-;(S)-2-AMino-3-(tritylthio)propanoic acid;(2S)-2-amino-3-tritylsulfanylpropanoicaci
- CBNumber
- CB91117670
- Molecular Formula
- C22H21NO2S
- Formula Weight
- 363.47
- MOL File
- 25840-82-8.mol
S-Trityl-D-cysteine Property
- Boiling point:
- 524.7±50.0 °C(Predicted)
- Density
- 1.232±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- pka
- 2.22±0.10(Predicted)
- form
- Solid
- color
- White to off-white
- optical activity
- Consistent with structure
- Water Solubility
- Sparingly soluble in water 0.022 g/L 25°C.
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 241749
- Product name
- S-Trityl-D-cysteine 99+%
- Packaging
- 1g
- Price
- $186
- Updated
- 2021/12/16
- Product number
- T887925
- Product name
- (-)-S-Trityl-D-cysteine
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- T887925
- Product name
- (-)-S-Trityl-D-cysteine
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 05952
- Product name
- -Trityl-D-cysteine
- Purity
- ≥ 98% (HPLC)
- Packaging
- 25G
- Price
- $45
- Updated
- 2021/12/16
- Product number
- AS112876
- Product name
- H-D-Cys(Trt)-OH
- Purity
- 97%
- Packaging
- 5G
- Price
- $34
- Updated
- 2021/12/16
S-Trityl-D-cysteine Chemical Properties,Usage,Production
Uses
(-)-S-Trityl-D-cysteine is used in medicine as intermediate. It inhibits the human mitotic kinesin Eg5.
Synthesis
76-84-6
921-01-7
2799-07-7
General procedure for the synthesis of S-triphenylmethyl-L-cysteine from triphenylmethanol and D-cysteine: D-cysteine (242.30 mg, 2.0 mmol) was placed in a single-necked flask, trifluoroacetic acid (TFA, 4 mL) was added and stirred at room temperature. Triphenylmethanol (520.68 mg, 2.0 mmol) was then added and the reaction continued to be stirred at room temperature for 2 hours. After completion of the reaction, the reaction mixture was cooled to 0 °C, anhydrous ether (30 mL) was added, and the pH was adjusted to 4-5 by slowly adding 4 N NaOH aqueous solution dropwise with stirring.Next, 10% saturated sodium acetate aqueous solution was added, and stirring was continued for 1 h to stabilize the pH at 5-6.The reaction mixture was filtered, and the filter cake was washed with anhydrous ether (30 mL × 2) to afford the white powdery product S Triphenylmethyl-L-cysteine (566.4 mg, yield: 77.90%).
References
[1] Patent: CN106432014, 2017, A. Location in patent: Paragraph 0199; 0200; 0201; 0202
S-Trityl-D-cysteine Preparation Products And Raw materials
Raw materials
Preparation Products
S-Trityl-D-cysteine Suppliers
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- Country
- India
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