ChemicalBook > CAS DataBase List > 8-Hydroxyquinoline-N-oxide

8-Hydroxyquinoline-N-oxide

Product Name
8-Hydroxyquinoline-N-oxide
CAS No.
1127-45-3
Chemical Name
8-Hydroxyquinoline-N-oxide
Synonyms
NSC 21656; NSC 2165;2-METHYLOXINE;OXINE N-OXIDE;1-Oxy-quinolin-8-ol;TIMTEC-BB SBB009099;8-Hydroxyquinoline-N;8-QUINOLINOL-1-OXIDE;8-QUINOLINOL N-OXIDE;Quinolin-8-ol N-oxide
CBNumber
CB9112579
Molecular Formula
C9H7NO2
Formula Weight
161.16
MOL File
1127-45-3.mol
More
Less

8-Hydroxyquinoline-N-oxide Property

Melting point:
135-138 °C (lit.)
Boiling point:
267 °C(lit.)
Density 
1.2480 (rough estimate)
refractive index 
1.5050 (estimate)
Flash point:
139 °C
storage temp. 
Inert atmosphere,2-8°C
solubility 
Soluble in Acetone, Chloroform, Dichloromethane, Ethyl Acetate and Methanol
pka
6.03±0.30(Predicted)
form 
Solid
color 
Yellow
BRN 
128737
CAS DataBase Reference
1127-45-3(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
N,Xi
Risk Statements 
50/53-36/37/38
Safety Statements 
60-61-24/25-22-36/37/39-27-26
RIDADR 
UN 3077 9/PG 3
WGK Germany 
3
RTECS 
VC8238500
3-10
HS Code 
29334900
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P270Do not eat, drink or smoke when using this product.

P272Contaminated work clothing should not be allowed out of the workplace.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P308+P313IF exposed or concerned: Get medical advice/attention.

P363Wash contaminated clothing before reuse.

P403Store in a well-ventilated place.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
122335
Product name
8-Quinolinol N-oxide
Purity
98%
Packaging
10g
Price
$126.8
Updated
2024/03/01
Sigma-Aldrich
Product number
122335
Product name
8-Quinolinol N-oxide
Purity
98%
Packaging
5g
Price
$175
Updated
2023/06/20
TCI Chemical
Product number
H1272
Product name
8-Hydroxyquinoline N-Oxide
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$48
Updated
2024/03/01
TCI Chemical
Product number
H1272
Product name
8-Hydroxyquinoline N-Oxide
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$151
Updated
2024/03/01
TRC
Product number
H953270
Product name
8-Hydroxyquinoline N-Oxide
Packaging
5g
Price
$80
Updated
2021/12/16
More
Less

8-Hydroxyquinoline-N-oxide Chemical Properties,Usage,Production

Description

A quinoline derivative that displays mutagenic activity. It suppresses luminescence of an indicator bacterium that is named Photobacterium phosphoreum. This chemical forms two kinds of complexes with palladium (II) and Gold (III). One kind is an ion-associated compound containing hydrogen bond and hte other is the six membered metal chelates containing metal-oxygen bonds.

Chemical Properties

Yellow Crystalline Solid

Uses

A quinoline derivative; shows mutagenic activity.

Definition

ChEBI: 8-hydroxyquinoline N-oxide is a quinoline N-oxide carrying a hydroxy substituent at position 8. It is a monohydroxyquinoline and a quinoline N-oxide. It is functionally related to a quinolin-8-ol. It is a conjugate acid of an 8-hydroxyquinoline N-oxide(1-).

General Description

8-Quinolinol N-oxide is a toxicant which can suppress luminescence of an indicator bacterium Photobacterium phosphoreum. It forms two types of complexes with gold(III) and palladium(II): type I are ion-associated compounds containing hydrogen bond and the other is the six-membered metal chelates containing metal-oxygen bonds.

Synthesis

8-hydroxyquinoline-N-oxide was synthesized from 8-hydroxyquinoline. A stirred solution of 8-hydroxyquinoline (25.00 g, 172.2 mmol) in 550 ml of CHCl3 was cooled to 0° C., and 3 -chloroperoxybenzoic acid (40.00 g, 80% Tech. grade *0.231 mmol=0.185 mmol) was added slowly over 3 minutes. The solution was kept at 0° C. and stirred for 3 hours. During this period, the 3-chlorobenzoic acid byproduct precipitated. The 3-chlorobenzoic acid was removed by filtration and the orange filtrate was concentrated to dryness and the remaining solid was triturated with 2% NH40 H (2*200 ml). The solid was isolated on a frit and washed with H2O.

8-Hydroxyquinoline-N-oxide Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

8-Hydroxyquinoline-N-oxide Suppliers

Nanjing Shengkai Pharmaceutical Technology Co., Ltd.
Tel
025-86182925 17749516701
Email
195645838@qq.com
Country
China
ProdList
154
Advantage
58
Jinan LuoHe PharmaTech Co., Ltd.
Tel
0531-68658065 15726150375
Fax
0531-68658065
Email
jinanluohe@163.com
Country
China
ProdList
488
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40240
Advantage
62
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2341
Advantage
56
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
Tel
0311-89250318 031166536426
Fax
4000311741
Email
master@sjzsdyn.com
Country
China
ProdList
2882
Advantage
65
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11660
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42982
Advantage
64
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
+8618575662672 18575662672
Fax
021 51613951
Email
mzeng@3wpharm.com
Country
China
ProdList
9742
Advantage
57
Shanghai Shenyue Chemical Co., Ltd.
Tel
021-021-52212593 15300879511
Fax
+86 (21) 51062076
Email
sales@nuohey.com
Country
China
ProdList
3933
Advantage
60
Chengdu Forest Science and Technology Development Co., Ltd.
Tel
18030648795 18030648795
Fax
028-61777050
Email
sales@cdforestchem.com
Country
China
ProdList
1393
Advantage
58
Shanghai Topbiochem Technology Co., Ltd
Tel
+86-21-60341587
Fax
+86-21-61294319
Email
sales@topbiochem.com
Country
China
ProdList
6181
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22519
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25014
Advantage
65
Acesys Pharmatech
Tel
18860950986
Email
tangmanman@zenjipharma.com
Country
China
ProdList
1735
Advantage
55
Runpharm Technology Limited
Tel
18171398856 2968382473
Fax
0086-21-50758330
Email
service@runpharm.com
Country
China
ProdList
718
Advantage
55
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9986
Advantage
55
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41438
Advantage
60
Shanghai DiBai Chemicals Co., Ltd.
Tel
021-54359730 400-008-9730
Fax
021-54353864
Email
info@chemxyz.com
Country
China
ProdList
3993
Advantage
60
Wuhan Dahua Pharmaceutical Co., Ltd.
Tel
027-59262863 13277907145 3091977954
Fax
027-59420980
Country
China
ProdList
4951
Advantage
58
Nanjing Chalf-Pharm Technology Co., Ltd.
Tel
025-57018978 18251899859
Fax
025-57018008
Email
sales@chalf-pharm.com
Country
China
ProdList
5917
Advantage
50
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
Giant chemicals
Tel
028-85434334 18108076537
Fax
QQ:245797092
Email
market@gianthx.com
Country
China
ProdList
4512
Advantage
56
Zhengzhou Alfachem Co., Ltd.
Tel
0371-53765687 18937137882
Fax
QQ:2885373884
Email
2853979813@qq.com
Country
China
ProdList
7978
Advantage
55
Henan CoreyChem Co., Ltd
Tel
0371-86658258
Fax
0371-60996044
Email
info@coreychem.com
Country
China
ProdList
10457
Advantage
58
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
Tel
0311-89250318 031166536426
Fax
4000311741
Email
master@sjzsdyn.com
Country
China
ProdList
3496
Advantage
58
Shanghai Xilong Biochemical Technology Co., Ltd.
Tel
021-52907766-8042
Fax
021-52906523
Country
China
ProdList
9947
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27322
Advantage
60
parabiochem
Tel
025-83453382-8005
Fax
025-83453382
Email
sale@parabiochem.com
Country
China
ProdList
9604
Advantage
55
Shandong Xiya Chemical Co., Ltd.
Tel
4009903999 13395398332
Fax
0539-6365991
Email
sales@xiyashiji.com
Country
China
ProdList
20810
Advantage
60
Chengdu Dianchun Technology Co., Ltd
Tel
400-1166-196 18502815961
Fax
QQ:800101999
Email
cdhxsj@163.com
Country
China
ProdList
14623
Advantage
60
Grader reagent
Tel
18221735425
Email
sales@xinpingchem.com
Country
China
ProdList
9951
Advantage
58
NanJing FineTech Chemical Co., Ltd
Tel
17714198479 17714198479
Email
sales@fine-chemtech.com
Country
China
ProdList
170
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131980
Advantage
58
Wuhan Wsem Biological Co., Ltd.
Tel
027-83778876 13667159345
Fax
027-83778876
Email
13667159345@163.com
Country
China
ProdList
1967
Advantage
55
Henan Anky Chemical Technology Co., Ltd.
Tel
17836913271
Fax
0374-8348899
Email
3224305243@qq.com
Country
China
ProdList
2790
Advantage
58
Taian Jiaye Biotechnology Co.Ltd
Tel
13127280945
Email
285424065@qq.com
Country
China
ProdList
9980
Advantage
55
Shandong Ono Chemical Co., Ltd.
Tel
0539-6362799 20)
Fax
0539-6362799(To 20)
Country
China
ProdList
9998
Advantage
58
Hangzhou Molcore Biopharmatech Co.,Ltd
Tel
400-711-5280 86-571-81025280
Fax
86-571-85806285
Email
sales@molcore.com
Country
China
ProdList
9974
Advantage
58
Shanghai Darui Fine Chemicals Co., Ltd.
Tel
021-33922791-0 13816046603
Email
3368239663@qq.com
Country
China
ProdList
4292
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
021-021-52271985 17721149837
Fax
+86 (21) 52271987
Email
sales@9dingchem.com
Country
China
ProdList
19806
Advantage
60
Shanghai BaiShun Biological Technology Co., Ltd
Tel
021-37581181
Fax
021-57456066
Email
sales@chem-mall.com
Country
China
ProdList
10335
Advantage
58
Jiaxing Deyi Chemical Co., Ltd.
Tel
0573-86-0573-85866609 13325730825
Fax
0573-85866609
Email
945717149@qq.com
Country
China
ProdList
7960
Advantage
58
Capot Chemical Co.,Ltd.
Tel
571-85586718 +8613336195806
Fax
+86-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
29797
Advantage
60
Shanghai Standard Technology Co.,Ltd.
Tel
021-021-57127007-6622-6622 15618937986
Fax
+86 (21) 5132-0077
Email
zhaok@nature-standard.com
Country
China
ProdList
3928
Advantage
58
Aikon International Limited
Tel
025-66113011 18112977050
Fax
(5)02557626880
Email
cb6@aikonchem.com
Country
China
ProdList
15495
Advantage
58
SHANGHAI FDC-CHEMICAL CO.,LTD
Tel
021-61469567 18521078705
Fax
021-61161605
Email
sales@fdc-chemical.com
Country
China
ProdList
19982
Advantage
58
Wuhan FengyaoTonghui Chemical Products Co., Ltd.
Tel
027-87466105 15377573527
Email
2678564200@qq.com
Country
China
ProdList
17997
Advantage
58
More
Less

View Lastest Price from 8-Hydroxyquinoline-N-oxide manufacturers

Hebei Duling International Trade Co. LTD
Product
8-Hydroxyquinoline-N-oxide 1127-45-3
Price
US $45.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000 tons
Release date
2023-02-02
Henan Bao Enluo International TradeCo.,LTD
Product
8-Hydroxyquinoline-N-oxide 1127-45-3
Price
US $100.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000tons
Release date
2023-06-19
Hebei Zhanyao Biotechnology Co. Ltd
Product
8-Hydroxyquinoline-N-oxide 1127-45-3
Price
US $100.00/Kg/Bag
Min. Order
1Kg/Bag
Purity
Above 99%
Supply Ability
5000kg/month
Release date
2021-03-08

1127-45-3, 8-Hydroxyquinoline-N-oxideRelated Search:


  • 8-hydroxyquinoleine-N-oxide
  • NSC 21656
  • 8-Hydroxyquinoline 1-Oxide
  • o-Hydroxyquinoline N-Oxide
  • 8-Hydroxychinolin-N-oxid
  • 1-oxido-8-quinolin-1-iumolate
  • 1-Oxidoquinolin-1-ium-8-ol
  • 1-Oxylato-8-hydroxyquinoline-1-ium
  • 8-Hydroxyquinoline-N-oxide,99%
  • 8-Hydroxyquinoline-N
  • Quinolin-8-ol N-oxide
  • 8-Quinolinol N-oxide 98%
  • 1-Oxy-quinolin-8-ol
  • 8-hydroxyquinoline-oxide
  • 8-QUINOLINOL-1-OXIDE
  • 8-QUINOLINOL N-OXIDE
  • 8-HYDROXY-2-METHYLQUINOLINE
  • 8-HYDROXYQUINOLINE-N-OXIDE
  • 8-HYDROXYQUINOLIN-N-OXIDE
  • 2-METHYL-8-HYDROXYQUINOLINE
  • 2-METHYLOXINE
  • OXINE N-OXIDE
  • quinolin-8-ol 1-oxide
  • TIMTEC-BB SBB009099
  • 8-HYDROXYQUINOLINE N-OXIDE 98%
  • NSC 2165
  • 8-HydroxyquinolineN-Oxide&gt
  • 8-Hydroxyquinoline-N-oxide ISO 9001:2015 REACH
  • Procaterol Impurity 38
  • 1127-45-3
  • Building Blocks
  • Alkylquinolines
  • Hydroxyquinolines
  • Quinolines
  • Heterocyclic Building Blocks
  • Quinaldines
  • Quinoline derivatives
  • Quinolines, Isoquinolines & Quinoxalines
  • Quinolines
  • Aromatics Compounds
  • Aromatics
  • Heterocycles
  • Mutagenesis Research Chemicals
  • Quinolines, Isoquinolines & Quinoxalines
  • Morpholines/Thiomorpholines