SPATHULENOL
Description Appearance Biological activity Uses- Product Name
- SPATHULENOL
- CAS No.
- 6750-60-3
- Chemical Name
- SPATHULENOL
- Synonyms
- Espatulenol;1H-Cycloprop(e)azulen-7-ol, decahydro-1,1,7-trimethyl-4-methylene-, (1aR-(1aalpha,4aalpha,7beta,7abeta,7balpha))-;Spathulrnol;(1aR,4aβ,7aα,7bβ)-Decahydro-1,1,7-trimethyl-4-methylene-1H-cycloprop[e]azulen-7α-ol;Spathulel;SPATHULENOL;(+)-Spathulenol;spathulenol,(+)-spathulenol,espatulenol;(1aR,4aR,7S,7aR,7bR)-1,1,7-Trimethyl-4-methylenedecahydro-1H-cyclopropa[e]azulen-7-ol;1H-Cycloprop[e]azulen-7-ol, decahydro-1,1,7-trimethyl-4-methylene-, (1aR,4aR,7S,7aR,7bR)-
- CBNumber
- CB91175245
- Molecular Formula
- C15H24O
- Formula Weight
- 220.35
- MOL File
- 6750-60-3.mol
SPATHULENOL Property
- Boiling point:
- 284.7 °C
- Density
- 1.02±0.1 g/cm3(Predicted)
- pka
- 15.10±0.40(Predicted)
- form
- Liquid
- color
- Colorless to light yellow
- Odor
- at 100.00 %. earthy herbal fruity
- Odor Type
- earthy
- InChI
- InChI=1S/C15H24O/c1-9-5-6-11-13(14(11,2)3)12-10(9)7-8-15(12,4)16/h10-13,16H,1,5-8H2,2-4H3/t10-,11+,12+,13+,15-/m0/s1
- InChIKey
- FRMCCTDTYSRUBE-BGPZULBFSA-N
- SMILES
- C1[C@]2([H])[C@]([H])([C@]3([H])C(C)(C)[C@]3([H])CCC2=C)[C@@](C)(O)C1
- LogP
- 4.406 (est)
N-Bromosuccinimide Price
- Product number
- FS63189
- Product name
- Spathulenol
- Packaging
- 2mg
- Price
- $300
- Updated
- 2021/12/16
- Product number
- CS-0016592
- Product name
- Spathulenol
- Packaging
- 1mg
- Price
- $343
- Updated
- 2021/12/16
- Product number
- FS63189
- Product name
- Spathulenol
- Packaging
- 5mg
- Price
- $550
- Updated
- 2021/12/16
- Product number
- W2200
- Product name
- Spathulenol
- Packaging
- 5mg
- Price
- $792
- Updated
- 2021/12/16
- Product number
- FS63189
- Product name
- Spathulenol
- Packaging
- 10mg
- Price
- $850
- Updated
- 2021/12/16
SPATHULENOL Chemical Properties,Usage,Production
Description
Spathulenol is a tricyclic sesquiterpene alcohol which has a basic skeleton similar to the azulenes,it occurs in oregano among other plants.
Appearance
Spathulenol is a colorless to pale yellow clear liquid.
Biological activity
Spathulenol is isolated from psidium guineense Sw, has antioxidant, anti-inflammatory, anti-proliferative and anti-mycobacterial activities. It shows high antioxidant activity in DPPH system with IC50 of 85.60 μg/mL.
Uses
Eucalyptol is an organic alcohol compound, mainly used for content determination and experimental research, not for other purposes.
Uses
Spathulenol is isolated from Aristolochia yunnanensis, and has antioxidant, anti-inflammatory, antiproliferative and antimycobacterial activities. Spathulenol shows a high antioxidant activity with an IC50 of 85.60 μg/mL in the DPPH system[1].
Definition
ChEBI: Spathulenol is a tricyclic sesquiterpenoid that is 4-methylidenedecahydro-1H-cyclopropa[e]azulene carrying three methyl substituents at positions 1, 1 and 7 as well as a hydroxy substituent at position 7. It has a role as a volatile oil component, a plant metabolite, an anaesthetic and a vasodilator agent. It is a sesquiterpenoid, a carbotricyclic compound, a tertiary alcohol and an olefinic compound.
in vivo
Spathulenol (oral administration; 300 mg/kg) shows a significant inhibition in the Cg-induced mice paw oedema and pleurisy model[1]. In a spontaneous lipoperoxidation rat brain homogenate model, when incubated in controlled temperature and oxygenation conditions, PG-1 exhibits a high activity with an IC50 value of 26.13 μg/mL, respectively, which is comparable to a commercial antioxidant BHT (38.41 μg/mL), Thus, PG-1 contributes to a decrease in the generation of MDA, which is a toxic product resulting from the degradation of the cell membrane by lipid peroxidation, causing cell ruptures and mutations[1].
References
[1] Nascimento KF, et al. Antioxidant, anti-inflammatory, antiproliferative and antimycobacterial activities of the essential oil of Psidium guineense Sw. and spathulenol.J Ethnopharmacol. 2018 Jan 10;210:351-358. DOI:10.1016/j.jep.2017.08.030
SPATHULENOL Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from SPATHULENOL manufacturers
- Product
- SPATHULENOL 6750-60-3
- Price
- US $8.00/KG
- Min. Order
- 1g
- Purity
- ＞98% HPLC
- Supply Ability
- kg--ton
- Release date
- 2020-02-20