N-Acetyl-L-cysteine ethyl ester
- Product Name
- N-Acetyl-L-cysteine ethyl ester
- CAS No.
- 59587-09-6
- Chemical Name
- N-Acetyl-L-cysteine ethyl ester
- Synonyms
- NACET;101242;Acetylcysteine Impurity H;ethyl acetyl-L-cysteinate;Ethyl N-acetyl-L-cysteinate;N-Acetylcysteine ethylester;Fenoxaprop-ethyl Impurity 17;N-Acetyl-L-cysteine Ethyl Este;N-Acetyl-L-cysteine ethyl ester;L-Cysteine, N-acetyl-, ethyl ester
- CBNumber
- CB91177502
- Molecular Formula
- C7H13NO3S
- Formula Weight
- 191.25
- MOL File
- 59587-09-6.mol
N-Acetyl-L-cysteine ethyl ester Property
- Melting point:
- 44.1-44.5 °C
- Boiling point:
- 337.6±32.0 °C(Predicted)
- Density
- 1.138±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMF: 30 mg/ml,DMSO: 30 mg/ml,PBS (pH 7.2): 10 mg/ml
- form
- A crystalline solid
- pka
- 9.17±0.10(Predicted)
- color
- White to off-white
- InChI
- InChI=1S/C7H13NO3S/c1-3-11-7(10)6(4-12)8-5(2)9/h6,12H,3-4H2,1-2H3,(H,8,9)/t6-/m0/s1
- InChIKey
- MSMRAGNKRYVTCX-LURJTMIESA-N
- SMILES
- C(OCC)(=O)[C@H](CS)NC(C)=O
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H372Causes damage to organs through prolonged or repeated exposure
H413May cause long lasting harmful effects to aquatic life
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 30299
- Product name
- N-acetyl-L-Cysteine ethyl ester
- Packaging
- 5mg
- Price
- $44
- Updated
- 2024/03/01
- Product number
- 30299
- Product name
- N-acetyl-L-Cysteine ethyl ester
- Packaging
- 10mg
- Price
- $84
- Updated
- 2024/03/01
- Product number
- 30299
- Product name
- N-acetyl-L-Cysteine ethyl ester
- Packaging
- 50mg
- Price
- $193
- Updated
- 2024/03/01
- Product number
- 30299
- Product name
- N-acetyl-L-Cysteine ethyl ester
- Packaging
- 100mg
- Price
- $363
- Updated
- 2024/03/01
- Product number
- 0446CB
- Product name
- L-Cysteine,N-acetyl-,ethylester
- Packaging
- 100mg
- Price
- $502
- Updated
- 2021/12/16
N-Acetyl-L-cysteine ethyl ester Chemical Properties,Usage,Production
Description
N-acetyl-L-Cysteine ethyl ester is an esterified form of N-acetyl-L-cysteine (NAC; ). It has enhanced cell permeability in isolated perfused rat liver compared to NAC. N-acetyl-L-Cysteine ethyl ester (1 mM) prevents tert-butyl hydroperoxide-induced formation of methemoglobin in isolated human red blood cells. It increases glutathione levels in rat liver, kidney, heart, testis, and brain when administered at a dose of 50 mg/kg twice per day for two weeks. N-acetyl-L-Cysteine ethyl ester reduces increases in plasma aspartate aminotransferase (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH) levels induced by paracetamol (acetaminophen; ) in rats.
Uses
N-Acetyl-L-cysteine ethyl ester is an esterified form of N-acetyl-L-cysteine (NAC). N-Acetyl-L-cysteine ethyl ester exhibits enhanced cell permeability, and produce NAC and cysteine. N-Acetyl-L-cysteine ethyl ester increases circulating hydrogen sulfide (H2S) and can be used as an H2S producer. N-Acetyl-L-cysteine ethyl ester has the potential to substitute NAC as a mucolytic agent, and as a GSH-related antioxidant[1].
References
[1] Daniela Giustarini, et al. N-Acetylcysteine ethyl ester (NACET): a novel lipophilic cell-permeable cysteine derivative with an unusual pharmacokinetic feature and remarkable antioxidant potential. Biochem Pharmacol. 2012 Dec 1;84(11):1522-33. DOI:10.1016/j.bcp.2012.09.010
N-Acetyl-L-cysteine ethyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from N-Acetyl-L-cysteine ethyl ester manufacturers
- Product
- N-Acetyl-L-cysteine ethyl ester 59587-09-6
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%min
- Supply Ability
- 20tons
- Release date
- 2025-10-22
- Product
- N-Acetyl-L-cysteine ethyl ester 59587-09-6
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 2000
- Release date
- 2025-06-06
- Product
- N-Acetyl-L-Cysteine Ethyl Ester 59587-09-6
- Price
- US $1.00-4.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200000KG
- Release date
- 2025-05-14