ChemicalBook > CAS DataBase List > N-Acetyl-L-cysteine ethyl ester

N-Acetyl-L-cysteine ethyl ester

Product Name
N-Acetyl-L-cysteine ethyl ester
CAS No.
59587-09-6
Chemical Name
N-Acetyl-L-cysteine ethyl ester
Synonyms
NACET;101242;Acetylcysteine Impurity H;ethyl acetyl-L-cysteinate;Ethyl N-acetyl-L-cysteinate;N-Acetylcysteine ethylester;Fenoxaprop-ethyl Impurity 17;N-Acetyl-L-cysteine Ethyl Este;N-Acetyl-L-cysteine ethyl ester;L-Cysteine, N-acetyl-, ethyl ester
CBNumber
CB91177502
Molecular Formula
C7H13NO3S
Formula Weight
191.25
MOL File
59587-09-6.mol
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N-Acetyl-L-cysteine ethyl ester Property

Melting point:
44.1-44.5 °C
Boiling point:
337.6±32.0 °C(Predicted)
Density 
1.138±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMF: 30 mg/ml,DMSO: 30 mg/ml,PBS (pH 7.2): 10 mg/ml
form 
A crystalline solid
pka
9.17±0.10(Predicted)
color 
White to off-white
InChI
InChI=1S/C7H13NO3S/c1-3-11-7(10)6(4-12)8-5(2)9/h6,12H,3-4H2,1-2H3,(H,8,9)/t6-/m0/s1
InChIKey
MSMRAGNKRYVTCX-LURJTMIESA-N
SMILES
C(OCC)(=O)[C@H](CS)NC(C)=O
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H372Causes damage to organs through prolonged or repeated exposure

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
30299
Product name
N-acetyl-L-Cysteine ethyl ester
Packaging
5mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
30299
Product name
N-acetyl-L-Cysteine ethyl ester
Packaging
10mg
Price
$84
Updated
2024/03/01
Cayman Chemical
Product number
30299
Product name
N-acetyl-L-Cysteine ethyl ester
Packaging
50mg
Price
$193
Updated
2024/03/01
Cayman Chemical
Product number
30299
Product name
N-acetyl-L-Cysteine ethyl ester
Packaging
100mg
Price
$363
Updated
2024/03/01
AK Scientific
Product number
0446CB
Product name
L-Cysteine,N-acetyl-,ethylester
Packaging
100mg
Price
$502
Updated
2021/12/16
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N-Acetyl-L-cysteine ethyl ester Chemical Properties,Usage,Production

Description

N-acetyl-L-Cysteine ethyl ester is an esterified form of N-acetyl-L-cysteine (NAC; ). It has enhanced cell permeability in isolated perfused rat liver compared to NAC. N-acetyl-L-Cysteine ethyl ester (1 mM) prevents tert-butyl hydroperoxide-induced formation of methemoglobin in isolated human red blood cells. It increases glutathione levels in rat liver, kidney, heart, testis, and brain when administered at a dose of 50 mg/kg twice per day for two weeks. N-acetyl-L-Cysteine ethyl ester reduces increases in plasma aspartate aminotransferase (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH) levels induced by paracetamol (acetaminophen; ) in rats.

Uses

N-Acetyl-L-cysteine ethyl ester is an esterified form of N-acetyl-L-cysteine (NAC). N-Acetyl-L-cysteine ethyl ester exhibits enhanced cell permeability, and produce NAC and cysteine. N-Acetyl-L-cysteine ethyl ester increases circulating hydrogen sulfide (H2S) and can be used as an H2S producer. N-Acetyl-L-cysteine ethyl ester has the potential to substitute NAC as a mucolytic agent, and as a GSH-related antioxidant[1].

References

[1] Daniela Giustarini, et al. N-Acetylcysteine ethyl ester (NACET): a novel lipophilic cell-permeable cysteine derivative with an unusual pharmacokinetic feature and remarkable antioxidant potential. Biochem Pharmacol. 2012 Dec 1;84(11):1522-33. DOI:10.1016/j.bcp.2012.09.010

N-Acetyl-L-cysteine ethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from N-Acetyl-L-cysteine ethyl ester manufacturers

HANGZHOU HAILAN CHEMICAL CO.,LTD.
Product
N-Acetyl-L-cysteine ethyl ester 59587-09-6
Price
US $0.00/kg
Min. Order
1kg
Purity
99%min
Supply Ability
20tons
Release date
2025-10-22
Shenzhen Nexcon Pharmatechs Ltd.
Product
N-Acetyl-L-cysteine ethyl ester 59587-09-6
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
2000
Release date
2025-06-06
Shaanxi Dideu Medichem Co. Ltd
Product
N-Acetyl-L-Cysteine Ethyl Ester 59587-09-6
Price
US $1.00-4.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200000KG
Release date
2025-05-14

59587-09-6, N-Acetyl-L-cysteine ethyl esterRelated Search:

Magnesium trisilicate (2R)-6,6-DIBROMO-3,3-DIMETHYL-4,4,7-TRIOXO-4-THIA-1-AZABICYCLO[3,2,0] HEPTANE-2-CARBOXYLIC ACID 4-NITROBENZYL ESTER (DES-GLY)-GLUTATHIONE-MONOETHYL ESTER (REDUCED) N-(3-nitratopivaloyl)cysteine ethyl ester N-Acetyl-L-cysteine ethyl ester CBZ-GLY-S-BENZYL-L-CYS ETHYL ESTER N-ACETYL-L-CYSTEINE ALLYL ESTER S-BENZYL-L-CYSTEINE-S-BENZYL-L-CYSTEINE ETHYL ESTER N-ACETYL-S-[3-(D-3)-ACETAMINO-6-HYDROXPHENYL]-CYSTEINE ALLYL ESTER, DEUTERATED CBZ-GLY-S-BENZYL-L-CYS-S-BENZYL-L-CYS ETHYL ESTER

  • ethyl (2R)-2-acetamido-3-sulfanylpropanoate
  • Acetylcysteine Impurity H
  • 101242
  • 2-acetamido-3-mercaptopropanoic acid ethyl ester
  • Ethyl N-acetyl-L-cysteinate
  • N-Acetyl-L-cysteine ethyl ester
  • L-Cysteine, N-acetyl-, ethyl ester
  • N-Acetylcysteine ethylester
  • (R)-ethyl 2-acetaMido-3-Mercaptopropanoate
  • (R)-Methyl 2-acetaMido-3-Mercaptopropanoate
  • -Ethyl 2-acetamido-3-mercaptopropanoate
  • ethyl acetyl-L-cysteinate
  • NACET
  • NACET Synonyms: N-Acetyl-L-cysteine ethyl ester
  • N-ethyl cool-L-cysteine ethyl ester
  • N-Acetyl-L-cysteine Ethyl Ester (NACET)
  • Fenoxaprop-ethyl Impurity 17
  • N-Acetyl-L-cysteine Ethyl Este
  • NACET N-Acetyl-L-cysteine ethyl ester
  • N-Acetyl-L-cysteine ethyl ester - [A71501]
  • 59587-09-6
  • 59587-09-6