Scutellarin

ChemicalBook > CAS DataBase List > Scutellarin

Product Name: Scutellarin
CAS No.: 27740-01-8
Chemical Name: Scutellarin
Synonyms: SCUTELLARIN;Scutellarin B;Scutellarin,NA;Scutellarin-RM;Scutellarin ,98%;Erigeron extract;Scutellarin Powder;Scutellarin USP/EP/BP;Scutellarin 27740-01-8;Scutellarin (6CI, 7CI)
CBNumber: CB9117918
Molecular Formula: C21H18O12
Formula Weight: 462.36
MOL File: 27740-01-8.mol

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Scutellarin Property

Melting point:: 300～301℃
Boiling point:: 891.6±65.0 °C(Predicted)
Density: 1.810±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,2-8°C
solubility: DMSO (Slightly), Methanol (Very Slightly, Sonicated)
pka: 2.72±0.70(Predicted)
form: Solid
color: Light Yellow to Yellow
BRN: 71779
CAS DataBase Reference: 27740-01-8(CAS DataBase Reference)

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Safety

Safety Statements: 24/25
WGK Germany: 3
HS Code: 29389090

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 73577
Product name: Scutellarin
Purity: analytical standard
Packaging: 10mg
Price: $290.4
Updated: 2024/03/01

Cayman Chemical

Product number: 27461
Product name: Scutellarin
Packaging: 10mg
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 27461
Product name: Scutellarin
Packaging: 100mg
Price: $426
Updated: 2024/03/01

Cayman Chemical

Product number: 27461
Product name: Scutellarin
Packaging: 25mg
Price: $172
Updated: 2024/03/01

Cayman Chemical

Product number: 27461
Product name: Scutellarin
Packaging: 50mg
Price: $257
Updated: 2024/03/01

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Scutellarin Chemical Properties,Usage,Production

Description

Scutellarin is a flavone that has been found in S. barbata and has diverse biological activities, including anticancer, lipid lowering, antioxidative, and neurocognitive properties. It inhibits proliferation of PC-9 and H1975 non-small cell lung cancer (NSCLC) cells in a concentration-dependent manner and induces apoptosis and autophagy when used at a concentration of 160 μM, effects that can be blocked by the autophagy inhibitor HCQ . Scutellarin (30 and 60 mg/kg per day) reduces tumor growth in an H1975 mouse xenograft model. It decreases serum total cholesterol and LDL-cholesterol and increases HDL-cholesterol in a high-fat diet-induced mouse model of non-alcoholic fatty liver disease (NAFLD) when administered at doses of 25 and 50 mg/kg. It decreases hepatic malondialdehyde (MDA), glutamic-oxalacetic transaminase (GOT), and glutamic-pyruvic transaminase (GPT) activity, increases catalase (CAT) and total antioxidative capacity (T-AOC) activity, and increases the hepatic expression of PPARγ, PGC-1α, and Nrf2 in the same model. Scutellarin (5, 25, and 50 mg/kg per day) also prevents deficits in spatial and novel object memory in rats in the Y maze and novel object recognition test, respectively.

Uses

Scutellarin is an active flavonoid component from the medical plant Erigeron breviscapus (Vant) Hand-Mazz. Scutellarin is used as a micrpcirculation promoter for the treatment of cardio-cerebrovascular diseases. Studies suggest that Scutellarin has anti-cancer properties and has been shown to enhance apoptosis of tumor cells.

Definition

ChEBI: The glycosyloxyflavone which is the 7-O-glucuronide of scutellarein.

Scutellarin Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Scutellarin manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: Scutellarin 27740-01-8
Price: US $200.00-85.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-04-23

BINBO BIOLOGICAL CO.,LTD

Product: Scutellarin 27740-01-8
Price: US $10.00/kg
Min. Order: 1kg
Purity: 95%
Supply Ability: 1000 kg
Release date: 2025-01-03

Hebei Shengyang Water Conservancy Engineering Co., Ltd.

Product: Scutellarin 27740-01-8
Price: US $18.00/kg
Min. Order: 1kg
Purity: 99.9
Supply Ability: 5000
Release date: 2024-05-10

27740-01-8, ScutellarinRelated Search:

Baicalin Baicalein SCUTELLAREIN Isoimperatorin Genistin Isoliquiritigenin 5,7-Dihydrox -4'-methoxyisoflavone FLAVONE APIGENIN-7-GLUCURONIDE Wogonoside Tetramethyl-O-scutellarin BAICALIN HYDRATE 3',5'-Dimethoxytricetin 7-O-β-D-glucopypranoside 7-HYDROXYFLAVONE-BETA-D-GLUCOSIDE BREVISCAPIN Scutellarin ERIGERON BREVISCAPUS SCUTELLARIN:>5%,DCQ:>5%

SCUTELLARIN, 98+% BY HPLC

(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl

β-D-Glucopyranosiduronicacid,5,6-dihydroxy-2-

4',5,6-Trihydroxy-7-[(β-D-glucopyranuronosyl)oxy]flavone

4',5,6-Trihydroxyflavon-7-yl β-D-glucopyranosiduronic acid

5,6-Dihydroxy-4-oxo-2-(4-hydroxyphenyl)-4H-1-benzopyran-7-yl β-D-glucopyranosiduronic acid

Scutellarein 4'-methyl ether 7-glucuronide

Scutellarein 7-glucuronide

SCUTELLARIN

SCUTELLAREIN 7-O-GLUCURONIDE

Scutellarin ,98%

Scutellarin B

7-(beta-d-glucopyranuronosyloxy)-5,6-dihydroxy-2-(4-hydroxyphenyl)-4h-1-benzopyran-4-one

Scutellarin 27740-01-8

Erigeron extract

4',5,6,7-Tetrahydroxyflavone 7-β-D-Glucopyranuronoside

5,6-Dihydroxy-2-(p-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl β-D-Glucopyranosiduronic Acid

Scutellarein 7-O-β-D-Glucuronide

Scutellarein 7-β-D-Glucuronoside

Scutellarein 7-b-D-glucuronide

Scutellarin 7-(beta-D-Glucopyranuronosyloxy)-5,6-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl-β-D-glucopyranosiduronic acid

7-(β-D-Glucopyranuronosyloxy)-5,6-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

β-D-Glucopyranosiduronic acid, 5,6-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl

Scutellarin USP/EP/BP

(2S,3S,4S,5R,6S)-6-((5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid

</SUP> Reference Substance

Scutellarin (6CI, 7CI)

Scutellarin Powder

Scutellarin,NA

Scutellarin-RM

27740-01-8

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chemical reagent

pharmaceutical intermediate

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