Scutellarin
- Product Name
- Scutellarin
- CAS No.
- 27740-01-8
- Chemical Name
- Scutellarin
- Synonyms
- SCUTELLARIN;Scutellarin B;Scutellarin ,98%;Erigeron extract;Scutellarin Powder;Scutellarin USP/EP/BP;Scutellarin 27740-01-8;Scutellarin (6CI, 7CI);SCUTELLARIN, 98+% BY HPLC;Scutellarein 7-glucuronide
- CBNumber
- CB9117918
- Molecular Formula
- C21H18O12
- Formula Weight
- 462.36
- MOL File
- 27740-01-8.mol
Scutellarin Property
- Melting point:
- 300～301℃
- Boiling point:
- 891.6±65.0 °C(Predicted)
- Density
- 1.810±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,2-8°C
- solubility
- DMSO (Slightly), Methanol (Very Slightly, Sonicated)
- pka
- 2.72±0.70(Predicted)
- color
- Light Yellow to Yellow
- BRN
- 71779
- CAS DataBase Reference
- 27740-01-8(CAS DataBase Reference)
Safety
- Safety Statements
- 24/25
- WGK Germany
- 3
- HS Code
- 29389090
N-Bromosuccinimide Price
- Product number
- 73577
- Product name
- Scutellarin
- Purity
- analytical standard
- Packaging
- 10mg
- Price
- $290.4
- Updated
- 2024/03/01
- Product number
- 27461
- Product name
- Scutellarin
- Packaging
- 10mg
- Price
- $44
- Updated
- 2024/03/01
- Product number
- 27461
- Product name
- Scutellarin
- Packaging
- 100mg
- Price
- $426
- Updated
- 2024/03/01
- Product number
- 27461
- Product name
- Scutellarin
- Packaging
- 25mg
- Price
- $172
- Updated
- 2024/03/01
- Product number
- 27461
- Product name
- Scutellarin
- Packaging
- 50mg
- Price
- $257
- Updated
- 2024/03/01
Scutellarin Chemical Properties,Usage,Production
Description
Scutellarin is a flavone that has been found in S. barbata and has diverse biological activities, including anticancer, lipid lowering, antioxidative, and neurocognitive properties. It inhibits proliferation of PC-9 and H1975 non-small cell lung cancer (NSCLC) cells in a concentration-dependent manner and induces apoptosis and autophagy when used at a concentration of 160 μM, effects that can be blocked by the autophagy inhibitor HCQ . Scutellarin (30 and 60 mg/kg per day) reduces tumor growth in an H1975 mouse xenograft model. It decreases serum total cholesterol and LDL-cholesterol and increases HDL-cholesterol in a high-fat diet-induced mouse model of non-alcoholic fatty liver disease (NAFLD) when administered at doses of 25 and 50 mg/kg. It decreases hepatic malondialdehyde (MDA), glutamic-oxalacetic transaminase (GOT), and glutamic-pyruvic transaminase (GPT) activity, increases catalase (CAT) and total antioxidative capacity (T-AOC) activity, and increases the hepatic expression of PPARγ, PGC-1α, and Nrf2 in the same model. Scutellarin (5, 25, and 50 mg/kg per day) also prevents deficits in spatial and novel object memory in rats in the Y maze and novel object recognition test, respectively.
Uses
Scutellarin is an active flavonoid component from the medical plant Erigeron breviscapus (Vant) Hand-Mazz. Scutellarin is used as a micrpcirculation promoter for the treatment of cardio-cerebrovascular diseases. Studies suggest that Scutellarin has anti-cancer properties and has been shown to enhance apoptosis of tumor cells.
Definition
ChEBI: The glycosyloxyflavone which is the 7-O-glucuronide of scutellarein.
Scutellarin Preparation Products And Raw materials
Raw materials
Preparation Products
Scutellarin Suppliers
View Lastest Price from Scutellarin manufacturers
- Product
- Scutellarin 27740-01-8
- Price
- US $18.00-18.00/kg
- Min. Order
- 1kg
- Purity
- 99.9
- Supply Ability
- 5000
- Release date
- 2024-05-10
- Product
- Scutellarin 27740-01-8
- Price
- US $200.00-85.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2024-04-23
- Product
- Scutellarin 27740-01-8
- Price
- US $20.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500MT/month
- Release date
- 2022-01-19