SCUTELLAREIN
- Product Name
- SCUTELLAREIN
- CAS No.
- 529-53-3
- Chemical Name
- SCUTELLAREIN
- Synonyms
- SCUTELLAREIN;Scutillarein;Scutellartln;isocarthamidin;High baicalein;Scutellarein-RM;6-HYDROXYAPIGENIN;SCUTELLAREIN WITH HPLC;SCUTELLAREIN, 98.0% BY HPLC;Scutellarein, 10 mM in DMSO
- CBNumber
- CB6402688
- Molecular Formula
- C15H10O6
- Formula Weight
- 286.24
- MOL File
- 529-53-3.mol
SCUTELLAREIN Property
- Melting point:
- 330°C
- Boiling point:
- 642.9±55.0 °C(Predicted)
- Density
- 1.654±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,2-8°C
- solubility
- DMSO: soluble1mg/mL, clear, greenish-yellow
- pka
- 6.34±0.40(Predicted)
- form
- powder
- color
- yellow
- biological source
- Erigeron breviscapus
- InChIKey
- JVXZRQGOGOXCEC-UHFFFAOYSA-N
- LogP
- 2.540 (est)
Safety
- Safety Statements
- 24/25
- WGK Germany
- 3
- HS Code
- 29329990
N-Bromosuccinimide Price
- Product number
- S0327
- Product name
- Scutellarein
- Purity
- ≥98% (HPLC)
- Packaging
- 10mg
- Price
- $348.52
- Updated
- 2025/07/31
- Product number
- S0327
- Product name
- Scutellarein
- Purity
- ≥98% (HPLC)
- Packaging
- 50mg
- Price
- $854
- Updated
- 2025/07/31
- Product number
- C3507
- Product name
- Scutellarein
- Packaging
- 10MG
- Price
- $148
- Updated
- 2025/07/31
- Product number
- C3507
- Product name
- Scutellarein
- Packaging
- 50MG
- Price
- $469
- Updated
- 2025/07/31
- Product number
- 24977
- Product name
- Scutellarein
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $36
- Updated
- 2024/03/01
SCUTELLAREIN Chemical Properties,Usage,Production
Description
Scutellarein is a flavone that has been isolated from S. baicalensis and has antioxidant, enzyme inhibitory, anti-inflammatory, and antiproliferative biological activities. It has antioxidant activity in a total reactive antioxidant potential (TRAP) assay when used at a concentration of 1 μg/ml. Scutellarein inhibits sucrose hydrolysis by rat intestinal α-glucosidase and ATPase activity of the severe acute respiratory syndrome (SARS) coronavirus helicase nsP13 (IC50s = 12 and 0.86 μM, respectively). It decreases nitric oxide (NO) release and mRNA expression of inducible NO synthase (iNOS) and TNF-α induced by LPS in RAW 264.7 macrophages when used at a concentration of 50 μM. In vivo, scutellarein (0.5 μg/g) decreases tumor weight and volume in an HT-1080 human fibrosarcoma mouse xenograft model.
Chemical Properties
Yellow solid
Uses
Scutellarein is a flavonoid that can be found in Scutellaria lateriflora. Scutellarein is a hydrolysis product of Scutellarein (S201900), its glucuronide conjugated analogue.
Definition
ChEBI: Flavone substituted with hydroxy groups at C-4', -5, -6 and -7.
References
[1] K M HUI H X X H Wang. Interaction of flavones from the roots of Scutellaria baicalensis with the benzodiazepine site.[J]. Planta medica, 2000, 66 1: 91-93. DOI: 10.1055/s-0029-1243121
[2] JACKELINE TIEMY GUINOZA SIRAICHI. Antioxidant capacity of the leaf extract obtained from Arrabidaea chica cultivated in Southern Brazil.[J]. PLoS ONE, 2013: e72733. DOI: 10.1371/journal.pone.0072733
[3] JUN KAWABATA. 6-hydroxyflavonoids as alpha-glucosidase inhibitors from marjoram (Origanum majorana) leaves.[J]. Bioscience, Biotechnology, and Biochemistry, 2003, 67 2: 445-447. DOI: 10.1271/bbb.67.445
[4] MI-SUN YU . Identification of myricetin and scutellarein as novel chemical inhibitors of the SARS coronavirus helicase, nsP13[J]. Bioorganic & Medicinal Chemistry Letters, 2012, 22 12: Pages 4049-4054. DOI: 10.1016/j.bmcl.2012.04.081
[5] NAK YOON SUNG Jae Y C Mi Yeon Kim. Scutellarein Reduces Inflammatory Responses by Inhibiting Src Kinase Activity.[J]. Korean Journal of Physiology & Pharmacology, 2015, 19 5: 441-449. DOI: 10.4196/kjpp.2015.19.5.441
[6] XIUJUAN SHI. Scutellarein inhibits cancer cell metastasis in vitro and attenuates the development of fibrosarcoma in vivo.[J]. International journal of molecular medicine, 2015, 35 1: 31-38. DOI: 10.3892/ijmm.2014.1997
SCUTELLAREIN Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from SCUTELLAREIN manufacturers
- Product
- Scutellarein 529-53-3
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2019-11-26
- Product
- SCUTELLAREIN 529-53-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2018-08-08