HISPIDULIN

Product Name: HISPIDULIN
CAS No.: 1447-88-7
Chemical Name: HISPIDULIN
Synonyms: Dinatin;HISPIDULIN;Hispedulin;Hispidulin-RM;Methoxyapigenin;Hispidulin, >99%;6-Methoxyapigenin;Hispidulin(Dinatin);6-Methylscutellarein;Hispidulin - Bio-X ?
CBNumber: CB6723941
Molecular Formula: C16H12O6
Formula Weight: 300.26
MOL File: 1447-88-7.mol

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HISPIDULIN Property

Melting point:: 291-292 °C
Boiling point:: 601.5±55.0 °C(Predicted)
Density: 1.512±0.06 g/cm3(Predicted)
storage temp.: -20°C
solubility: DMSO: soluble20mg/mL, clear
pka: 6.51±0.40(Predicted)
form: powder
color: white to beige
InChI: InChI=1S/C16H12O6/c1-21-16-11(19)7-13-14(15(16)20)10(18)6-12(22-13)8-2-4-9(17)5-3-8/h2-7,17,19-20H,1H3
InChIKey: IHFBPDAQLQOCBX-UHFFFAOYSA-N
SMILES: C1(C2=CC=C(O)C=C2)OC2=CC(O)=C(OC)C(O)=C2C(=O)C=1

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Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: 3
RTECS: DJ2996000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0582
Product name: Hispidulin
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $136.8
Updated: 2025/07/31

Sigma-Aldrich

Product number: SML0582
Product name: Hispidulin
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $558
Updated: 2025/07/31

Cayman Chemical

Product number: 26383
Product name: Hispidulin
Packaging: 5mg
Price: $86
Updated: 2024/03/01

Cayman Chemical

Product number: 26383
Product name: Hispidulin
Packaging: 25mg
Price: $305
Updated: 2024/03/01

Cayman Chemical

Product number: 26383
Product name: Hispidulin
Packaging: 1mg
Price: $32
Updated: 2024/03/01

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HISPIDULIN Chemical Properties,Usage,Production

Chemical Properties

Yellow crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, from the lychee grass extracted from the inside of the Asteraceae plant ragweed whole grass, snow lotus.

Uses

Hispidulin has been used as a calibration standard:

in high-performance liquid chromatography (HPLC) for quantification of Clerodendrum petasites flavonoids
in liquid chromatography/electrospray ionization mass spectrometry (LC/ESI-MS) analysis
in reverse-phase high-performance liquid chromatography with a diode-array detector (HPLC-DAD) and high-performance thin-layer chromatography (HPTLC)

Definition

ChEBI: A monomethoxyflavone that is scutellarein methylated at position 6.

General Description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Biological Activity

Partial positive allosteric modulator at the benzodiazepine receptor (IC 50 = 1.3 μ M for inhibition of flumazenil binding); natural sage flavone. Stimulates GABA-induced chloride currents in Xenopus oocytes expressing α 1 α 2-, α 3-, α 5- or α 6- β 2 γ 2S GABA A receptors. Brain penetrant; oral administration reduces seizures in a gerbil model of epilepsy. Also has antifungal, antiproliferative, antioxidant and antithrombotic properties.

Biochem/physiol Actions

Hispidulin is a bioactive flavonoid with a variety of effects including antiproliferative, antifungal, anti-inflammatory, antioxidative and antiepileptic activity. Like EGCG, hispidulin appears to activate AMPK and inhibit the PI3K/Akt/mTOR pathway. The antiepileptic activity may be due to additional activity as a benzodiazepine (BZD) receptor ligand.

HISPIDULIN Preparation Products And Raw materials

Raw materials

Preparation Products

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HISPIDULIN Suppliers

China 214 Europe 2 Germany 3 India 1 United Kingdom 5 United States 13 Global 238

Shanghai Tauto Biotech Co., Ltd.

Tel: 021-51320588
Fax: 0086-21-51320502
Email: tauto@tautobiotech.com
Country: China
ProdList: 3988
Advantage: 66

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15838
Advantage: 69

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6003
Advantage: 61

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18729
Advantage: 57

BioBioPha Co., Ltd.

Tel: 0871-65217109 13211707573;
Fax: 0871-65215563
Email: y.liu@mail.biobiopha.com
Country: China
ProdList: 5653
Advantage: 65

Chengdu Biopurify Phytochemicals Ltd.

Tel: +86-028-82633397 18982077548
Fax: +86-28-82633165
Email: cwb1@biopurify.cn
Country: China
ProdList: 2376
Advantage: 60

Chengdu Climax Biotech Co., Ltd.

Tel: 028-83311324 1278112614
Fax: 028-83311324
Email: climaxbiotech@gmail.com
Country: China
ProdList: 925
Advantage: 58

Shanghai Winherb Medical Technology Co., Ltd.

Tel: 021-38218169 13341702378
Fax: QQ：190129269
Email: winherb@126.com
Country: China
ProdList: 1245
Advantage: 58

Beijing HuaMeiHuLiBiological Chemical

Tel: 010-56205725
Fax: 010-65763397
Email: waley188@sohu.com
Country: China
ProdList: 12335
Advantage: 58

China Kouting Group Limited

Tel: +86 (21) 5811-6473 5811-6475
Fax: +86 (21) 6129-4103
Email: sales@koutingchina.com
Country: China
ProdList: 496
Advantage: 60

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View Lastest Price from HISPIDULIN manufacturers

Shanghai Standard Technology Co., Ltd.

Product: Hispidulin 1447-88-7
Price: US $0.00/mg
Min. Order: 20mg
Purity: ≥98%(HPLC)
Supply Ability: 100 g
Release date: 2020-08-13

Career Henan Chemical Co

Product: HISPIDULIN 1447-88-7
Price: US $6.60/KG
Min. Order: 500g
Purity: 98%
Supply Ability: 1kg, 50kg, 100kg
Release date: 2019-12-25

1447-88-7, HISPIDULINRelated Search:

APIGENIN 6-GLUCOSYL-7-O-METHYL ETHER cirsimaritin 6,7-DIMETHOXY-3',4',5-TRIHYDROXYFLAVONE 3'-BENZYLOXY-4',5,6,7-TETRAMETHOXYFLAVONE 3',4',5',5,6,7-HEXAMETHOXYFLAVONE 6-METHOXYLUTEOLIN 3',4',5',6,7,8-HEXAMETHOXY-5-HYDROXYFLAVONE HISPIDULIN CASTICIN HINOKIFLAVONE 3',5-DIHYDROXY-4',6,7-TRIMETHOXYFLAVONE EUPATORIN-5-METHYL ETHER SCUTELLAREIN TETRAMETHYL ETHER SCUTELLAREIN Tangeretin 3,3',4',5,6,7,8-heptamethoxyflavone salvigenin SINENSETIN

SCUTELLAREIN 6-METHYL ETHER

4',5,7-Trihydroxy-6-methoxyflavone

5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one

6-Methoxyapigenin

6-Methylscutellarein

Hispidulin(Dinatin)

Methoxyapigenin

Dinatin

Hispedulin

HISPIDULIN

Hispidulin, >99%

4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-

5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxychromen-4-one

Hispidulin-RM

Hispidulin, 10 mM in DMSO

Hispidulin - Bio-X ?

1447-88-7

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