Indinavir sulfate

Product Name: Indinavir sulfate
CAS No.: 157810-81-6
Chemical Name: Indinavir sulfate
Synonyms: IDV;MK-639;CS-535;CS-1357;CRIXIVAN;MK-639 sulfate;MK-639,Crixivan;L735524 sulfate;INDINAVIR SULFATE;INDINAVIR SULPHATE
CBNumber: CB9123498
Molecular Formula: C36H49N5O8S
Formula Weight: 711.87
MOL File: 157810-81-6.mol

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Indinavir sulfate Property

Melting point:: 150-153°C (dec)
storage temp.: -20°C Freezer
solubility: Freely soluble in water, soluble in methanol, practically insoluble in heptane.
form: Solid
color: White to Off-White
Water Solubility: >100g/L(temperature not stated)
BCS Class: 2,4

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Safety

Hazardous Substances Data: 157810-81-6(Hazardous Substances Data)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 15150
Product name: Indinavir (sulfate)
Purity: ≥98%
Packaging: 1g
Price: $57
Updated: 2024/03/01

Cayman Chemical

Product number: 15150
Product name: Indinavir (sulfate)
Purity: ≥98%
Packaging: 5g
Price: $120
Updated: 2024/03/01

Cayman Chemical

Product number: 15150
Product name: Indinavir (sulfate)
Purity: ≥98%
Packaging: 500mg
Price: $36
Updated: 2024/03/01

TRC

Product number: I525000
Product name: IndinavirSulfate
Packaging: 10g
Price: $165
Updated: 2021/12/16

Usbiological

Product number: I0797-50
Product name: Indinavir Sulfate
Packaging: 5mg
Price: $319
Updated: 2021/12/16

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Indinavir sulfate Chemical Properties,Usage,Production

Description

Indinavir is an HIV-1 protease inhibitor (K_i = 0.358 nM). It is selective for HIV-1 protease over HIV-2 protease (K_i = 3.316 nM), as well as human cathepsin D, porcine pepsin, bovine chymosin, human plasma renin, Factor Xa, and elastase at 10 μM. It is also selective for wild-type HIV-1 protease over the protease inhibitor-resistant mutants A-44, K-60, and V-18 (K_is = 0.24, 15, 50, and 40 nM, respectively). Indinavir is active against multiple HIV-1 variants in cell-based assays (IC₉₅s = 12-100 nM). Formulations containing indinavir have been used in combination with antiretroviral agents in the treatment of HIV infection.

Chemical Properties

Crystalline Solid

Uses

Indinavir Sulfate is a member of the novel hydroxyaminopentane amide class of HIV-1 protease inhibitors. Antiviral. It is a COVID19-related research product.

Definition

ChEBI: Indinavir sulfate is an azaheterocycle sulfate salt. It is functionally related to an indinavir.

brand name

Crixivan (Merck).

Hazard

Moderately toxic by ingestion.

storage

RT

References

[1] J P VACCA. L-735,524: an orally bioavailable human immunodeficiency virus type 1 protease inhibitor.[J]. Proceedings of the National Academy of Sciences of the United States of America, 1994, 91 9: 4096-4100. DOI: 10.1073/pnas.91.9.4096
[2] BRUCE D. DORSEY. Identification of MK-944a: A Second Clinical Candidate from the Hydroxylaminepentanamide Isostere Series of HIV Protease Inhibitors[J]. Journal of Medicinal Chemistry, 2000, 43 18: 3386-3399. DOI: 10.1021/jm9903848

Indinavir sulfate Preparation Products And Raw materials

Raw materials

Preparation Products

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Indinavir sulfate Suppliers

Canada 1 China 147 Europe 2 Germany 1 India 8 South Korea 1 United Kingdom 8 United States 33 Global 201

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
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3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
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Chembest Research Laboratories Limited

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LGM Pharma

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Shanghai Hanhong Scientific Co.,Ltd.

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Chemsky（shanghai）International Co.,Ltd.

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China DongFan Chemical Co.,LTD

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Hangzhou Yuhao Chemical Technology Co., Ltd

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Dalian Meilun Biotech Co., Ltd.

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Shanghai Topbiochem Technology Co., Ltd

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Email: sales@topbiochem.com
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View Lastest Price from Indinavir sulfate manufacturers

Dideu Industries Group Limited

Product: Indinavir sulfate 157810-81-6
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons Min
Release date: 2021-07-15

Zhuozhou Wenxi import and Export Co., Ltd

Product: Indinavir sulfate 157810-81-6
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-11

Zhuozhou Wenxi import and Export Co., Ltd

Product: Indinavir sulfate 157810-81-6
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

157810-81-6, Indinavir sulfateRelated Search:

Zinc sulphate Barium sulfate Dimethyl sulfate Sodium thiosulfate pentahydrate Metformin Magnesium sulfate heptahydrate Ammonium sulfate Sodium sulfate Magnesium sulfate Dimethyl carbonate Dimethyl fumarate Dibutyl phthalate Indinavir CHLOROPHOSPHONAZO III Copper(II) sulfate Dimethylamine Aluminum sulfate Ferrous sulfate heptahydrate

CRIXIVAN

INDINAVIR SULFATE

INDINAVIR SULPHATE

(1(1s,2r),5(s))-2,3,5-trideoxy-n-(2,3-dihydro-2-hydroxy-1h-inden-1-yl)-5-(2-(((1,1-dimethylethyl)amino)carbonyl)-4-(3-pyridinylmethyl)-1-piperazinyl)-2-(phenylmethyl)-d-erythro-pentonamide sulfate

MK-639

indinavirsulfate(subjecttopatentfree)

IDV

MK-639,Crixivan

2,3,5-Trideoxy-N-[(1S,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl]-5-[(2S)-2[[(1,1-dimethylethyl)amino]carbonyl]-4-(3-pyridinylmethyl)-1-piperazinyl]-2-(phenylmethyl)-D-erythro-pentonamide

Indinavir sulfate 157810-81-6

N-tert-butyl-1-[2-hydroxy-5-[(2-hydroxy-2,3-dihydro-1H-inden-1-yl)amino]-5-oxo-4-(phenylmethyl)pentyl]-4-(3-pyridinylmethyl)-2-piperazinecarboxamide

CS-1357

Indinavir, MK 639, L 735524

CS-535

(2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-5-[[(1S,2R)-2-hydroxyindan-1-yl]amino]-5-oxo-pentyl]-N-tert-butyl-4-(3-pyridylmethyl)piperazine-2-carboxamide

INDIGOWOADROOTEXTRACT

Indinavir sulfate###Unii-9mg78X43zt

Indinavir sulfate ethanolate

Indinavir & Indinavir Sulfate

L735524 sulfate

MK-639 sulfate

Indinavir sulfate USP/EP/BP

(2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-5-[[(1S,2R)-2-hydroxyinda...

Indinavir sulfateQ: What is Indinavir sulfate Q: What is the CAS Number of Indinavir sulfate Q: What is the storage condition of Indinavir sulfate

D-erythro-Pentonamide, 2,3,5-trideoxy-N-[(1S,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl]-5-[(2S)-2-[[(1,1-dimethylethyl)amino]carbonyl]-4-(3-pyridinylmethyl)-1-piperazinyl]-2-(phenylmethyl)-, sulfate (1:1)

(S)-1-((2S,4R)-4-Benzyl-2-hydroxy-5-(((1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl)amino)-5-oxopentyl)-N-(tert-butyl)-4-(pyridin-3-ylmethyl)piperazine-2-carboxamide sulfate

Indinavir sulfate, 10 mM in DMSO

Levetiracetam (Injection Grade)

157810-81-6

156818-25-2

C36H47N5O4H2O4S

C36H47N5O4

C36H47N5O4H2SO4

C36H49N5O8S

Active Pharmaceutical Ingredients

Indinavir

peptides

Other APIs

Anti-viral Compounds

Anti-virals

Inhibitors

Intermediates & Fine Chemicals

Non-nucleoside Reverse Transcriptase

Pharmaceuticals

Coronavirus