2-Chloro-m-toluidine.
- Product Name
- 2-Chloro-m-toluidine.
- CAS No.
- 29027-17-6
- Chemical Name
- 2-Chloro-m-toluidine.
- Synonyms
- 2-Chloro-m-toluidine.;2-chloro-3-aminotoluene;2-Cloro-3-methylaniline;2-Chloro-3-methyl-benzenamine;Benzenamine,2-chloro-3-methyl-
- CBNumber
- CB91241090
- Molecular Formula
- C7H8ClN
- Formula Weight
- 141.6
- MOL File
- 29027-17-6.mol
2-Chloro-m-toluidine. Property
- Melting point:
- 6.6 °C
- Boiling point:
- 219.8±20.0 °C(Predicted)
- Density
- 1.180±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- Chlorooform (Sparingly), Methanol (Slightly)
- pka
- 2.78±0.10(Predicted)
- form
- liquid
- color
- Light yellow to yellow green
- InChI
- InChI=1S/C7H8ClN/c1-5-3-2-4-6(9)7(5)8/h2-4H,9H2,1H3
- InChIKey
- RQRKMXABSUYQBV-UHFFFAOYSA-N
- SMILES
- C1(N)=CC=CC(C)=C1Cl
Safety
- HS Code
- 2921420090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- C602205
- Product name
- 2-Chloro-3-methylaniline
- Packaging
- 50mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- FC158635
- Product name
- 2-Chloro-3-methylaniline
- Packaging
- 1g
- Price
- $80
- Updated
- 2021/12/16
- Product number
- 3730-5-53
- Product name
- 2-Chloro-3-methylaniline
- Purity
- 97%
- Packaging
- 5G
- Price
- $144
- Updated
- 2021/12/16
- Product number
- FC158635
- Product name
- 2-Chloro-3-methylaniline
- Packaging
- 2g
- Price
- $144
- Updated
- 2021/12/16
- Product number
- FC158635
- Product name
- 2-Chloro-3-methylaniline
- Packaging
- 5G
- Price
- $260
- Updated
- 2021/12/16
2-Chloro-m-toluidine. Chemical Properties,Usage,Production
Chemical Properties
The chloromethylanilines are colorless or white crystalline solids or liquids, some have a mild fishy odor.
Synthesis
3970-40-9
29027-17-6
General procedure for the synthesis of 2-chloro-3-methylaniline (CAS: 29027-17-6) from 2-chloro-3-nitrotoluene: 2-chloro-1-methyl-3-nitrobenzene (1 eq.) was dissolved in acetic acid (0.5 M) followed by addition of iron powder (4 eq.). The reaction mixture was heated to reflux at 100 °C for 2 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure and methanol was added to the residue. The mixture was stirred at room temperature for 12 hours and then filtered. The filtrate was concentrated and purified by silica gel column chromatography to afford 2-chloro-3-methylaniline in 60% yield, the product was a red oil.1H NMR (400 MHz, DMSO-d6) δ ppm: 6.90 (t, J = 7.7 Hz, 1H), 6.66 (d, J = 7.9 Hz, 1H), 6.50 (d, J = 7.4 Hz, 1H). 5.23 (brs, 2H), 2.24 (s, 3H).
Potential Exposure
Most of the isomers are used in dyestuff manufacture. The 3-chloro-para isomer is used to kill birds. It is marketed as pelleted bait for control of bird populations.
Shipping
UN2239 Chlorotoluidines, solid, Hazard Class: 6.1; Labels: 6.1-Poisonous materials. UN3429 Chlorotoluidines, liquid, Hazard Class: 6.1; Labels: 6.1- Poisonous materials
Incompatibilities
Incompatible with oxidizers, strong acids; chloroformates, and acid anhydrides, isocyanates, aldehydes forming fire and explosive hazards.
References
[1] Organic Letters, 2014, vol. 16, # 17, p. 4420 - 4423
[2] Patent: US2016/96841, 2016, A1. Location in patent: Paragraph 0349
[3] Journal of the Chemical Society, 1901, vol. 79, p. 1128
[4] Journal of the Chemical Society, 1902, vol. 81, p. 1327,1347
[5] Recueil des Travaux Chimiques des Pays-Bas, 1913, vol. 32, p. 247
2-Chloro-m-toluidine. Preparation Products And Raw materials
Raw materials
Preparation Products
2-Chloro-m-toluidine. Suppliers
- Tel
- 021-33758897
- sales@scochem.com
- Country
- China
- ProdList
- 1596
- Advantage
- 58
- Tel
- 010-59484199 18611897322
- sales@eternalchem.com
- Country
- China
- ProdList
- 4383
- Advantage
- 60
- Tel
- 021-58170097
- info@topbiochem.com
- Country
- China
- ProdList
- 9510
- Advantage
- 58
- Tel
- 021-60343070
- Fax
- 021-35122006
- Country
- China
- ProdList
- 12740
- Advantage
- 55
- Tel
- 0510-0510-86396359 13382276200
- sales@jalor-chem.com
- Country
- China
- ProdList
- 996
- Advantage
- 56
- Tel
- +1-510-219-6317
- Fax
- +1-650-486-1361
- sales@hbcchem.com
- Country
- United States
- ProdList
- 10648
- Advantage
- 60
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 42446
- Advantage
- 60
- Tel
- 021-021-56795766
- Fax
- +86-21-56795266
- sales@worldyachem.com
- Country
- China
- ProdList
- 9476
- Advantage
- 58
- Tel
- 18905173768
- Fax
- 025-83263139
- 52513593@qq.com
- Country
- China
- ProdList
- 2331
- Advantage
- 50
- Tel
- 13912302692
- Fax
- 0519-88064678
- sales@anxuanchem.com
- Country
- China
- ProdList
- 4828
- Advantage
- 58