Ursolic acid acetate
- Product Name
- Ursolic acid acetate
- CAS No.
- 7372-30-7
- Chemical Name
- Ursolic acid acetate
- Synonyms
- Aids070315;Aids-070315;Acetylursolicaci;3-Acetylursolic acid;URSOLIC ACID ACETATE;Acetylursolic acid、Ursolic acetate;3β-(Acetyloxy)urs-12-en-28-oic acid;Ursolic acid acetate, 10 mM in DMSO;(3β)-3-(Acetyloxy)-urs-12-en-28-oic acid;URSOLIC ACID ACETATE (ACETYLURSOLIC ACID)
- CBNumber
- CB91463427
- Molecular Formula
- C32H50O4
- Formula Weight
- 498.74
- MOL File
- 7372-30-7.mol
Ursolic acid acetate Property
- Melting point:
- 279-280 °C
- Boiling point:
- 567.6±50.0 °C(Predicted)
- Density
- 1.09±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Powder
- pka
- 4.67±0.70(Predicted)
- color
- White to off-white
N-Bromosuccinimide Price
- Product number
- 30220
- Product name
- 3-Acetylursolic Acid
- Packaging
- 25mg
- Price
- $684
- Updated
- 2024/03/01
- Product number
- 30220
- Product name
- 3-Acetylursolic Acid
- Packaging
- 50mg
- Price
- $1139
- Updated
- 2024/03/01
- Product number
- 30220
- Product name
- 3-Acetylursolic Acid
- Packaging
- 5mg
- Price
- $153
- Updated
- 2024/03/01
- Product number
- 30220
- Product name
- 3-Acetylursolic Acid
- Packaging
- 10mg
- Price
- $290
- Updated
- 2024/03/01
- Product number
- U850115
- Product name
- UrsolicAcidAcetate
- Packaging
- 1mg
- Price
- $65
- Updated
- 2021/12/16
Ursolic acid acetate Chemical Properties,Usage,Production
Uses
Ursolic acid acetate (Acetylursolic acid), isolated from the aerial roots of Ficus microcarpa, exhibits cytotoxicity against KB cells with IC50 of 8.4 μM[1].
Definition
ChEBI: Acetylursolic acid is a triterpenoid.
Synthesis
77-52-1
108-24-7
915-79-7
Acetylation of ursolic acid (5.00 g, 10.96 mmol) with acetic anhydride (2.60 mL, 26.00 mmol) in pyridine (80 mL) was carried out by adding triethylamine (3.00 mL, 21.68 mmol) and a catalytic amount of DMAP for a 12 h reaction at 25°C. The reaction was carried out by aqueous post-treatment. Upon completion of the reaction, an aqueous post-treatment and purification by silica gel column chromatography (SiO2, eluent: hexane/ethyl acetate, 8:2) afforded the target compound 14 (5.30 g, 97% yield) as a colorless solid. Thin layer chromatography (TLC) showed Rf = 0.71 (SiO2, eluent: hexane/ethyl acetate, 7:3). The melting point of the compound is 235-238°C (literature value:[8] 242-244°C). Specific optical rotation [α]D = +64.89° (c = 0.86, CHCl3) (literature value:[8] [α]D = +71.2° (c = 1.0, CHCl3)). Mass spectra (ESI, MeOH) showed m/z = 499.1 (15%, [M + H]+), 521.3 (30%, [M + Na]+), 1019.3 (100%, [2M + Na]+).
References
[1] Chiang YM, et al. Cytotoxic triterpenes from the aerial roots of Ficus microcarpa. Phytochemistry. 2005 Feb;66(4):495-501. DOI:10.1016/j.phytochem.2004.12.026
Ursolic acid acetate Preparation Products And Raw materials
Raw materials
Preparation Products
Ursolic acid acetate Suppliers
- Tel
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- sales@carbosynth.com
- Country
- United Kingdom
- ProdList
- 6005
- Advantage
- 58
- Tel
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- Fax
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- info@apinchemicals.com
- Country
- United Kingdom
- ProdList
- 6807
- Advantage
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- Tel
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- info@apinchemicals.com
- Country
- United Kingdom
- ProdList
- 6184
- Advantage
- 60
View Lastest Price from Ursolic acid acetate manufacturers
- Product
- Ursolic acid acetate 7372-30-7
- Price
- US $6.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1kg, 10kg ,50kg
- Release date
- 2020-03-09