Benzene, 1-bromo-4-(1,1-difluoroethyl)-
- Product Name
- Benzene, 1-bromo-4-(1,1-difluoroethyl)-
- CAS No.
- 1000994-95-5
- Chemical Name
- Benzene, 1-bromo-4-(1,1-difluoroethyl)-
- Synonyms
- 1-Bromo-4-(1,1-difluoroethyl);4-(1,1-Difluoroethyl)bromobenzene;Bromo-4-(1,1-difluoroethyl)benzene;4-(1,1-Difluoroethyl)phenyl bromide;Benzene, 1-bromo-4-(1,1-difluoroethyl)-;1-Bromo-4-(1,1-difluoroethyl)benzene 95%;4-Bromo-alpha,alpha-difluoroethylbenzene
- CBNumber
- CB91465658
- Molecular Formula
- C8H7BrF2
- Formula Weight
- 221.04
- MOL File
- 1000994-95-5.mol
Benzene, 1-bromo-4-(1,1-difluoroethyl)- Property
- Boiling point:
- 219.0±30.0 °C(Predicted)
- Density
- 1.495 g/mL at 25 °C
- refractive index
- n20/D1.503
- Flash point:
- 82℃
- storage temp.
- Sealed in dry,Room Temperature
- form
- Powder or Crystalline Powder
- color
- Brown
- InChI
- InChI=1S/C8H7BrF2/c1-8(10,11)6-2-4-7(9)5-3-6/h2-5H,1H3
- InChIKey
- QXIBKCFAFRHORF-UHFFFAOYSA-N
- SMILES
- C1(Br)=CC=C(C(F)(F)C)C=C1
Safety
- RIDADR
- UN 2810 6.1 / PGIII
- WGK Germany
- 3
- HazardClass
- 6.1
- HS Code
- 29036990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 729949
- Product name
- 1-Bromo-4-(1,1-difluoroethyl)benzene
- Purity
- 95%
- Packaging
- 1g
- Price
- $54.46
- Updated
- 2025/07/31
- Product number
- B997180
- Product name
- 1-Bromo-4-(1,1-difluoroethyl)benzene
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- B997180
- Product name
- 1-Bromo-4-(1,1-difluoroethyl)benzene
- Packaging
- 500mg
- Price
- $155
- Updated
- 2021/12/16
- Product number
- 054391
- Product name
- 1-Bromo-4-(1,1-difluoroethyl)benzene
- Packaging
- 500mg
- Price
- $47
- Updated
- 2021/12/16
- Product number
- 1700-B-21
- Product name
- 1-Bromo-4-(1,1-difluoroethyl)benzene
- Packaging
- 1g
- Price
- $68
- Updated
- 2021/12/16
Benzene, 1-bromo-4-(1,1-difluoroethyl)- Chemical Properties,Usage,Production
Synthesis
99-90-1
1000994-95-5
Example 63A Synthesis of 1-bromo-4-(1,1-difluoroethyl)benzene: Under argon protection, 3.0 g (15.07 mmol) of 1-(4-bromophenyl)ethanone was dissolved in 30 mL of dichloromethane, followed by the slow addition of 15.9 mL (120.57 mmol) of [ethyl (trifluoro-lambda4-thioalkyl)amino]ethane (DAST). The reaction mixture was slowly warmed to 50 °C and stirred at this temperature overnight. Upon completion of the reaction, the reaction mixture was slowly poured into ice water. The organic phase was separated and the aqueous phase was extracted three times with dichloromethane. The organic phases were combined and dried with magnesium sulfate. After filtration, the solvent was removed by concentration under reduced pressure. The crude product was purified by silica gel column chromatography (eluent: petroleum ether/dichloromethane=4:1) to afford 2.56 g (11.58 mmol, 77% yield) of 1-bromo-4-(1,1-difluoroethyl)benzene as a pale yellow liquid. gC-MS (Method 1): rt = 2.84 min; m/z = 220/222 (M)+.
References
[1] Patent: US2012/172448, 2012, A1. Location in patent: Page/Page column 34
[2] Patent: US2010/305111, 2010, A1. Location in patent: Page/Page column 26
[3] Patent: US2011/21489, 2011, A1. Location in patent: Page/Page column 34-35
[4] Patent: EP2921489, 2015, A1. Location in patent: Paragraph 0110; 0111
[5] Patent: WO2015/160665, 2015, A1. Location in patent: Paragraph 00211
Benzene, 1-bromo-4-(1,1-difluoroethyl)- Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Benzene, 1-bromo-4-(1,1-difluoroethyl)- manufacturers
- Product
- Benzene, 1-bromo-4-(1,1-difluoroethyl)- 1000994-95-5
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1000kg
- Release date
- 2025-06-11
- Product
- 1-bromo-4-(1,1-difluoroethyl)benzene 1000994-95-5
- Price
- US $0.00/G
- Min. Order
- 1G
- Purity
- 98%min
- Supply Ability
- 30kg/month
- Release date
- 2023-02-03
- Product
- Benzene, 1-bromo-4-(1,1-difluoroethyl)- 1000994-95-5
- Price
- US $80.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-27