6-BROMOIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID
- Product Name
- 6-BROMOIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID
- CAS No.
- 749849-14-7
- Chemical Name
- 6-BROMOIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID
- Synonyms
- BUTTPARK 154\50-31;6-bromo-2-imidazo[1,2-a]pyridinecarboxylic acid;6-BROMOIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID;6-Bromoimidazo[1,2-a]pyridine-2-carboxylicacid 97%;IMidazo[1,2-a]pyridine-2-carboxylic acid, 6-broMo-;6-BROMOIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID, 95+%;6-Bromoimidazo[1,2-a]pyridine-2-carboxylicacidhydrate,95%;6-BroMoiMidazo[1,2-a]pyridine-2-carboxylic acid hydrate, 95%
- CBNumber
- CB9146581
- Molecular Formula
- C8H5BrN2O2
- Formula Weight
- 241.04
- MOL File
- 749849-14-7.mol
6-BROMOIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID Property
- Density
- 1.89
- storage temp.
- 2-8°C
- pka
- -4.73±0.41(Predicted)
- Appearance
- Off-white to light brown Solid
- CAS DataBase Reference
- 749849-14-7(CAS DataBase Reference)
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- B699755
- Product name
- 6-Bromoimidazo[1,2-a]pyridine-2-carboxylicAcid
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- B699755
- Product name
- 6-Bromoimidazo[1,2-a]pyridine-2-carboxylicAcid
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 071822
- Product name
- 6-Bromoimidazo[1,2-a]pyridine-2-carboxylic acid
- Purity
- 95+%
- Packaging
- 1g
- Price
- $100
- Updated
- 2021/12/16
- Product number
- OR110722
- Product name
- 6-Bromoimidazo[1,2-a]pyridine-2-carboxylicacid
- Purity
- 98%
- Packaging
- 1g
- Price
- $108
- Updated
- 2021/12/16
- Product number
- 4H21-9-03
- Product name
- 6-Bromo-imidazo[1,2-a]pyridine-2-carboxylic acid
- Purity
- 95%
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
6-BROMOIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID Chemical Properties,Usage,Production
Synthesis
67625-37-0
749849-14-7
General procedure for the synthesis of 6-bromoimidazo[1,2-a]pyridine-2-carboxylic acid from ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate: ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate (200 mg, 0.74 mmol) was dissolved in a mixed solvent of tetrahydrofuran (2 mL) and methanol (2 mL), and lithium hydroxide (42 mg) was added. 0.98 mmol) in aqueous solution (2 mL). The reaction mixture was stirred at 60°C overnight. Upon completion of the reaction, the volatile solvent was removed by rotary evaporation. The residue was diluted with water and acidified to pH 4 with aqueous 1 N hydrochloric acid.The precipitate was collected by filtration, washed with water and dried under vacuum to afford 6-bromoimidazo[1,2-a]pyridine-2-carboxylic acid (0.125 g, 70% yield). The intermediate could be directly used in the subsequent reaction without further purification.LC-MS analysis showed a single absorption peak at 254 nm, and the measured molecular ion peak (MH+) was 241, which was in accordance with the theoretically calculated value (C8H5BrN2O2).
References
[1] Bioorganic and Medicinal Chemistry Letters, 2006, vol. 16, # 21, p. 5598 - 5601
[2] Patent: WO2011/50245, 2011, A1. Location in patent: Page/Page column 99
6-BROMOIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
6-BROMOIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID Suppliers
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View Lastest Price from 6-BROMOIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID manufacturers
- Product
- 6-BROMOIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID 749849-14-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95-99%
- Supply Ability
- 1ton
- Release date
- 2020-01-02