6-Iodoquinazolin-4-one

Product Name: 6-Iodoquinazolin-4-one
CAS No.: 16064-08-7
Chemical Name: 6-Iodoquinazolin-4-one
Synonyms: 6-Iodoquin;TIMTEC-BB SBB005376;6-Iodoquinazolinone;6-IODO-4-QUINAZOLONE;6-Iodo-4-quinazolinol;6-iodoquinazolin-4-ol;6-lodoquinazolin-4-ol;6-IODOQUINAZOLIN-4-ONE;6-Iodo-4-quinazolinone;6-lodoquinazolin-4-one
CBNumber: CB9168046
Molecular Formula: C8H5IN2O
Formula Weight: 272.04
MOL File: 16064-08-7.mol

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6-Iodoquinazolin-4-one Property

Melting point:: 271°C(lit.)
Boiling point:: 401.0±47.0 °C(Predicted)
Density: 2.11±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
form: Solid
pka: 1.00±0.20(Predicted)
color: White to Off-White
InChI: InChI=1S/C8H5IN2O/c9-5-1-2-7-6(3-5)8(12)11-4-10-7/h1-4H,(H,10,11,12)
InChIKey: PUGXMZKDRVGIHC-UHFFFAOYSA-N
SMILES: N1C2=C(C=C(I)C=C2)C(=O)NC=1
CAS DataBase Reference: 16064-08-7(CAS DataBase Reference)

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Safety

Risk Statements: 36
Safety Statements: 26
HS Code: 2914390090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: I0832
Product name: 6-Iodo-4-hydroxyquinazoline
Purity: >97.0%(GC)(T)
Packaging: 5g
Price: $59
Updated: 2025/07/31

TRC

Product number: I719580
Product name: 6-Iodoquinazolin-4-one
Packaging: 25g
Price: $1190
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 46875
Product name: 6-Iodoquinazolin-4-one
Packaging: 2.5g
Price: $650
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0027754
Product name: 6-IODOQUINAZOLIN-4-ONE
Purity: 95.00%
Packaging: 2.5G
Price: $880
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0027754
Product name: 6-IODOQUINAZOLIN-4-ONE
Purity: 95.00%
Packaging: 25G
Price: $2425.5
Updated: 2021/12/16

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6-Iodoquinazolin-4-one Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

6-Iodoquinazolin-4-one is an intermediate in the synthesis of Lapatinib (L175800).

Synthesis

5326-47-6

149-73-5

16064-08-7

Using 2-amino-5-iodobenzoic acid and trimethyl orthoformate as starting materials, the synthesis procedure of Examples I-2 was followed, but the reaction solvent was replaced from methanol to acetonitrile. Upon completion of the reaction, 6-iodoquinazolin-4-one was obtained by post-processing in a yield of 0.98 g and 94% yield.

References

[1] Patent: EP1477481, 2004, A1. Location in patent: Page 17
[2] Patent: EP1477481, 2004, A1. Location in patent: Page 16-17
[3] Patent: EP1477481, 2004, A1. Location in patent: Page 17
[4] Patent: EP1477481, 2004, A1. Location in patent: Page 17
[5] Patent: EP1477481, 2004, A1. Location in patent: Page 17

6-Iodoquinazolin-4-one Preparation Products And Raw materials

Raw materials

Potassium hydroxide Sodium bisulfite Iodine Acetic acid Anthranilic acid Formamide

Preparation Products

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6-Iodoquinazolin-4-one Suppliers

Americas 1 Canada 2 China 202 Europe 1 Germany 1 India 5 Japan 1 The Netherlands 1 United Kingdom 2 United States 22 Global 238

Henan Evonik Biotechnology Co. LTD

Tel: 15672878902
Email: hnyingchuang@163.com
Country: China
ProdList: 3905
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Energy Chemical

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Email: sales8178@energy-chemical.com
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Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
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JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
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Adamas Reagent, Ltd.

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Email: chenyj@titansci.com
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Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
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Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 15883
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Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

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View Lastest Price from 6-Iodoquinazolin-4-one manufacturers

Nanjing Fred Technology Co., Ltd

Product: 6-Iodoquinazolin-4-one 16064-08-7
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1 ton
Release date: 2023-12-29

Hebei Chuanghai Biotechnology Co,.LTD

Product: 6-Iodoquinazolin-4-one 16064-08-7
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000kg
Release date: 2024-08-23

LY Global chemicals co.,ltd .

Product: 6-Iodoquinazolin-4-one 16064-08-7
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98.0%min
Supply Ability: 100kg
Release date: 2023-03-11

16064-08-7, 6-Iodoquinazolin-4-oneRelated Search:

Cefazolin sodium salt Cefazolin Naphazoline hydrochloride 6-Bromoquinazolin-4-ol 6-iodoquinazoline 6-IODO-2,4-DIMETHOXYQUINAZOLINE 6-Iodoquinazolin-4-one N-(6-IODO-8-METHYL-4-OXO-1,4-DIHYDRO-QUINAZOLIN-2-YL)-ISOBUTYRAMIDE 2-IODO-7,8,9,10-TETRAHYDROAZEPINO[2,1-B]QUINAZOLIN-12(6H)-ONE 6-IODO-2-METHYL-1H-QUINAZOLIN-4-ONE SALOR-INT L135879-1EA 6,8-DIIODO-4-QUINAZOLONE ZERENEX E/6026490 2-Ethyl-6-iodo-3-(2-((1-methylethyl)amino)ethyl)-4(3H)-quinazolinone 3-(2-(Ethylamino)ethyl)-6-iodo-2-methyl-4(3H)-quinazolinone 2-AMINO-6-IODO-8-METHYL-1H-QUINAZOLIN-4-ONE

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TIMTEC-BB SBB005376

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6-IODOQUINAZOLIN-4-ONE

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6-iodoquinazolin-4-ol

[4-[bis[4-(diethylamino)phenyl]methylene]cyclohexa-2,5-dien-1-ylidene]-diethyl-ammonium chloride

[4-[bis[4-(diethylamino)phenyl]methylidene]cyclohexa-2,5-dien-1-ylidene]-diethylazanium chloride

[4-[bis[4-(diethylamino)phenyl]methylidene]cyclohexa-2,5-dien-1-ylidene]-diethyl-azanium chloride

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2-METHYL-6-(CHLOROMETHYL)PYRIDINE HCL

6-Iodoquinazolinone

6-Iodo-4-hydroxyquinazoline

6-iodo-3,4-dihydroquinazolin-4-one

6-Iodo-4-hydroxyquinazoline&gt

6-Iodo-4ah-quinazolin-4-one

6-Iodo-4-quinazolinone

6-Iodoquinazolin-4-one ISO 9001：2015 REACH

6-lodoquinazolin-4-ol

6-lodoquinazolin-4-one

6-Iodoquinazolin-4-ol 98%

16064-08-7

pharmacetical

Lapatinib