6-iodoquinazoline
- Product Name
- 6-iodoquinazoline
- CAS No.
- 848841-54-3
- Chemical Name
- 6-iodoquinazoline
- Synonyms
- 6-iodoquinazoline;Quinazoline, 6-iodo-
- CBNumber
- CB61518728
- Molecular Formula
- C8H5IN2
- Formula Weight
- 256.04
- MOL File
- 848841-54-3.mol
6-iodoquinazoline Property
- Boiling point:
- 329.1±15.0 °C(Predicted)
- Density
- 1.938±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- pka
- 3.65±0.26(Predicted)
- Appearance
- Light yellow to yellow Solid
N-Bromosuccinimide Price
- Product number
- W8756
- Product name
- 6-Iodoquinazoline
- Packaging
- 1g
- Price
- $253
- Updated
- 2021/12/16
- Product number
- 072240
- Product name
- 6-Iodoquinazoline
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $370
- Updated
- 2021/12/16
- Product number
- 072240
- Product name
- 6-Iodoquinazoline
- Purity
- 95+%
- Packaging
- 1g
- Price
- $798
- Updated
- 2021/12/16
- Product number
- HCH0143424
- Product name
- 6-IODOQUINAZOLINE
- Purity
- 95.00%
- Packaging
- 250MG
- Price
- $984.06
- Updated
- 2021/12/16
- Product number
- HCH0143424
- Product name
- 6-IODOQUINAZOLINE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $1455.3
- Updated
- 2021/12/16
6-iodoquinazoline Chemical Properties,Usage,Production
Synthesis
253-82-7
848841-54-3
General procedure for the synthesis of 6-iodoquinazoline from quinazoline: N-iodosuccinimide (NIS, 5.4 g, 24 mmol) was slowly added to a solution of quinazoline (2.1 g, 16.13 mmol) in concentrated sulfuric acid (16 mL) at 0 °C. The reaction mixture was stirred at 0 °C for 10 min before gradually warming to room temperature and continued stirring for 15 h. The reaction mixture was then mixed with NIS (2.4 g, 16.13 mmol). Subsequently, NIS (2.0 g, 8.9 mmol) was added supplementally and the mixture was continued to stir for 5 hours. After completion of the reaction, the mixture was slowly poured into crushed ice (80 g) and stirred for 1 hour. The resulting solution was filtered, the pH was adjusted to 7 with concentrated ammonia and stirred for another 1 hour at 0°C. It was filtered again and the solids were washed with ice-cold water. Finally, the solid was air dried to give 6-iodoquinazoline (3.4 g, 87% yield). The product was confirmed by 1H NMR (400 MHz, DMSO) and mass spectrometry (MS ESI m/z 256 [M+H]+, C6H3IN4).
References
[1] Patent: WO2005/28444, 2005, A1. Location in patent: Page/Page column 56
6-iodoquinazoline Preparation Products And Raw materials
Raw materials
Preparation Products
6-iodoquinazoline Suppliers
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View Lastest Price from 6-iodoquinazoline manufacturers
- Product
- 6-iodoquinazoline 848841-54-3
- Price
- US $9.80/KG
- Min. Order
- 1g
- Purity
- ≥99%
- Supply Ability
- 100kg
- Release date
- 2020-01-12