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CAMPESTEROL

Product Name
CAMPESTEROL
CAS No.
474-62-4
Chemical Name
CAMPESTEROL
Synonyms
Campesterin;Ergost-5-en-3-ol;24α-methyl Cholesterol;(24R)-Ergost-5-en-3β-ol;C01789;CAMPESTROL;CAMPESTEROL;Campasterol;Mieyajunsu A;-17-((2R,5R)
CBNumber
CB9168763
Molecular Formula
C28H48O
Formula Weight
400.69
MOL File
474-62-4.mol
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CAMPESTEROL Property

Melting point:
156-160 °C
alpha 
D23 -33° (22.5 mg in 5 ml chloroform)
Boiling point:
463.29°C (rough estimate)
Density 
0.98±0.1 g/cm3 (20 ºC 760 Torr)
refractive index 
1.5100 (estimate)
storage temp. 
-20°C
solubility 
Chloroform (Sparingly), Methanol (Slightly, Sonicated)
pka
15.03±0.70(Predicted)
form 
crystalline
color 
white
biological source
Glycine max (soybean)
Merck 
13,1736
BRN 
3216975
InChIKey
SGNBVLSWZMBQTH-ZRUUVFCLSA-N
LogP
9.972 (est)
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Safety

Hazard Codes 
Xn,T
Risk Statements 
20/21/22-36/37/38-48/20/22-40-38-22
Safety Statements 
26-36-45-36/37/39-23
RIDADR 
UN 1888 6.1/PG 3
WGK Germany 
3
HS Code 
29061990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C5157
Product name
Campesterol
Purity
~65%
Packaging
1mg
Price
$130
Updated
2024/03/01
Sigma-Aldrich
Product number
C5157
Product name
Campesterol
Purity
~65%
Packaging
5mg
Price
$360
Updated
2024/03/01
Cayman Chemical
Product number
17344
Product name
24α-methyl Cholesterol
Purity
≥95%
Packaging
1mg
Price
$71
Updated
2023/06/20
Cayman Chemical
Product number
17344
Product name
24α-methyl Cholesterol
Purity
≥95%
Packaging
5mg
Price
$229
Updated
2023/06/20
Sigma-Aldrich
Product number
C5157
Product name
Campesterol
Purity
~65%
Packaging
10mg
Price
$599
Updated
2024/03/01
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CAMPESTEROL Chemical Properties,Usage,Production

Description

24α-methyl Cholesterol is a phytosterol found in vegetables, fruits, nuts, and seeds that competitively inhibits the absorption of intestinal cholesterol and decreases the transcription of genes important for cholesterol metabolism. The cholesterol lowering effects of phytosterols, such as 24α-methyl cholesterol, have been reported to be beneficial for lowering the incidence of atherosclerotic plaques. 24α-methyl Cholesterol can also act as an agonist at liver X receptors (LXR) and, through activation of LXR signaling, has been shown to suppress the proliferation of prostate and breast cancer cells.

Chemical Properties

White Solid

Uses

A phytosterol, which may inhibit the intestinal absorption of cholesterol.

Uses

Campesterol may be used as a plant sterol to test its effect on the transcriptional activation of liver X receptor α (LXRA) in breast cancer cells. It may also be used as a sterol standard for calibration curve generation in liquid chromatography multiple reaction monitoring (LC-MRM) analysis.

Definition

ChEBI: Campesterol is a member of phytosterols, a 3beta-sterol, a 3beta-hydroxy-Delta(5)-steroid and a C28-steroid. It has a role as a mouse metabolite. It derives from a hydride of a campestane.

General Description

Campesterol is a plant sterol, which is an analog of cholesterol and a brassinosteroid (BR) precursor. The enzyme diminute/dwarf1 mediates the synthesis of campesterol from 24-methylenecholesterol. Campesterol possesses methyl group at C-24 position of the side chain in the cholesterol structure.

Biochem/physiol Actions

Campesterol is a phytosterol, primarily found in nuts, fruits, legumes and seeds. Though an analogue of cholesterol, it is poorly absorbed in humans and competitively inhibits the absorption of cholesterol. Campesterol decreases the transcription of genes involved in cholesterol metabolism in hepatocytes and enterocytes and has positive impact in treatment of cardiovascular disease.

Purification Methods

Campesterol is recrystallised twice from hexane and once from Me2CO. The benzoyl derivative has m 158-160o [] D 23 -8.6o (CHCl3), and the acetyl derivative has m 137138o (EtOH) and [] D 23 -35.1o (c 2.9, CHCl3) [Fernholz & MacPhillamy J Am Chem Soc 6 3 1155 1941]. [Beilstein 6 III 2680.]

CAMPESTEROL Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from CAMPESTEROL manufacturers

HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Product
CAMPESTEROL 474-62-4
Price
US $980.00-750.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000
Release date
2024-08-15
Shaanxi Dideu Medichem Co. Ltd
Product
CAMPESTEROL 474-62-4
Price
US $1.00-22.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100000KG
Release date
2024-08-02
Nanjing Sky Hope Tongyuan Biological Engineering Co., Ltd.
Product
Campesterol 474-62-4
Price
US $70.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
10kg
Release date
2020-06-13

474-62-4, CAMPESTEROLRelated Search:

Campesterol,?95+％,CAMPESTEROL(P),CAMPESTEROL 1X1ML CHLOROFORM 100UG/ML beta-Sitosterol, with ca. 10% campesterol, ca. 75% beta-sitosterol,SS-SITOSTEROL: 45% (CONTAINS CAMPESTEROL),beta-Sitosterol (contains Campesterol) beta-Sitosterol Acetate (contains Campesterol) Campesterol-25,26,26,26,27,27,27-D7 CAMPESTEROL-D3 7-Campesterol Campesteryl-D-glucoside Campesteryl-D-glucoside-6’-palmitate Campesteryl palmitate Campesteryl ferulate Δ8-Campesterol 7-KETO-BETA-CAMPESTEROL 7-ALPHA-HYDROXY-BETA-CAMPESTEROL Campesterol (24-methyl-D3) DELTA7-CAMPESTEROL campesterol acetate 5,6-DIHYDROXY-BETA-CAMPESTEROL 5,6-ALPHA/BETA-EPOXY-BETA-CAMPESTEROL

  • (24R)-5-Ergosten-3beta-ol
  • (24R)-Methylcholest-5-en-3beta-ol
  • 24alpha-Methylcholesterol
  • Campesterin
  • DELTA5-24-Isoergosten-3beta-ol
  • Ergost-5-en-3beta-ol, (24R)-
  • Ergost-5-en-3-ol
  • Ergost-5-en-3-ol, (3beta,24R)-
  • ERGOST-5-EN-3-BETA-OL
  • ERGOST-5-EN-3B-OL
  • CAMPESTEROL
  • CAMPESTROL
  • 5-CHOLESTEN-24-ALPHA-METHYL 3-BETA-OL
  • 5-CHOLESTEN-24A-METHYL-3BETA-OL
  • 5-CHOLESTEN-24A-METHYL-3B-OL
  • 24ALPHA-METHYL-5-CHOLESTEN-3BETA-OL
  • 24(R)-ERGOST-5-EN-3BETA-OL
  • Campesterol from Glycine max (soybean)
  • campesterol from soybean
  • 24α-methyl-5-cholesten-3β-ol
  • 17-(5,6-dimethylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
  • 24α-Methyl-5-cholesten-3β-ol, 24(R)-Ergost-5-en-3β-ol
  • Campesterol solution
  • (24R)-24-Methylcholest-5-en-3β-ol
  • (24R)-24-Methylcholesterol
  • (24R)-Ergost-5-en-3β-ol
  • Δ5-Campesterol
  • C01789
  • Campesterol,24α-Methyl-5-cholesten-3β-ol, 24(R)-Ergost-5-en-3β-ol
  • CaMpesterol, froM Brassica caMpestris L.
  • 5-Cholesten-24(RS)-Methyl-3-ol-d7
  • CaMpest-5-en-3-ol
  • Mieyajunsu A
  • Campasterol
  • Campesterol, 98%, from Brassica campestris L.
  • Ergost-5-en-3-ol, (3,24R)-
  • Campesterol, >=98%
  • (8R,9S,10S,13R,14S,17R)
  • -10,13-dimethyl-4,5,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol
  • -17-((2R,5R)
  • -5,6-Dimethylheptan-2-yl)
  • (24R)-5-ERGOSTEN-3Β-OL
  • (3S,8S,9S,10R,13R,14S,17R)-17-((2R,5R)-5,6-dimethylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol
  • 24α-methyl Cholesterol
  • Campesterol 474-62-4
  • first-classCampesterol
  • CampesterolQ: What is Campesterol Q: What is the CAS Number of Campesterol Q: What is the storage condition of Campesterol Q: What are the applications of Campesterol
  • (24R)-5-Ergosten-3β-ol
  • Campesterol (6CI)
  • 5-Cholesten-24α-methyl 3β-ol
  • Ergost-5-en-3-ol, (3β,24R)-
  • Canola sterol
  • Campesterol-RM
  • 24(R)-Methylcholesterol
  • Ergost-5-En-3β-Ol
  • 474-62-4
  • C28H41D7O
  • BioChemical