CAMPESTEROL
- Product Name
- CAMPESTEROL
- CAS No.
- 474-62-4
- Chemical Name
- CAMPESTEROL
- Synonyms
- Campesterin;Ergost-5-en-3-ol;24α-methyl Cholesterol;(24R)-Ergost-5-en-3β-ol;C01789;CAMPESTROL;CAMPESTEROL;Campasterol;Mieyajunsu A;-17-((2R,5R)
- CBNumber
- CB9168763
- Molecular Formula
- C28H48O
- Formula Weight
- 400.69
- MOL File
- 474-62-4.mol
CAMPESTEROL Property
- Melting point:
- 156-160 °C
- alpha
- D23 -33° (22.5 mg in 5 ml chloroform)
- Boiling point:
- 463.29°C (rough estimate)
- Density
- 0.98±0.1 g/cm3 (20 ºC 760 Torr)
- refractive index
- 1.5100 (estimate)
- storage temp.
- -20°C
- solubility
- Chloroform (Sparingly), Methanol (Slightly, Sonicated)
- pka
- 15.03±0.70(Predicted)
- form
- crystalline
- color
- white
- Merck
- 13,1736
- BRN
- 3216975
- InChIKey
- SGNBVLSWZMBQTH-ZRUUVFCLSA-N
- LogP
- 9.972 (est)
Safety
- Hazard Codes
- Xn,T
- Risk Statements
- 20/21/22-36/37/38-48/20/22-40-38-22
- Safety Statements
- 26-36-45-36/37/39-23
- RIDADR
- UN 1888 6.1/PG 3
- WGK Germany
- 3
- HS Code
- 29061990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- C5157
- Product name
- Campesterol
- Purity
- ~65%
- Packaging
- 1mg
- Price
- $130
- Updated
- 2024/03/01
- Product number
- C5157
- Product name
- Campesterol
- Purity
- ~65%
- Packaging
- 5mg
- Price
- $360
- Updated
- 2024/03/01
- Product number
- 17344
- Product name
- 24α-methyl Cholesterol
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $71
- Updated
- 2023/06/20
- Product number
- 17344
- Product name
- 24α-methyl Cholesterol
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $229
- Updated
- 2023/06/20
- Product number
- C5157
- Product name
- Campesterol
- Purity
- ~65%
- Packaging
- 10mg
- Price
- $599
- Updated
- 2024/03/01
CAMPESTEROL Chemical Properties,Usage,Production
Description
24α-methyl Cholesterol is a phytosterol found in vegetables, fruits, nuts, and seeds that competitively inhibits the absorption of intestinal cholesterol and decreases the transcription of genes important for cholesterol metabolism. The cholesterol lowering effects of phytosterols, such as 24α-methyl cholesterol, have been reported to be beneficial for lowering the incidence of atherosclerotic plaques. 24α-methyl Cholesterol can also act as an agonist at liver X receptors (LXR) and, through activation of LXR signaling, has been shown to suppress the proliferation of prostate and breast cancer cells.
Chemical Properties
White Solid
Uses
A phytosterol, which may inhibit the intestinal absorption of cholesterol.
Uses
Campesterol may be used as a plant sterol to test its effect on the transcriptional activation of liver X receptor α (LXRA) in breast cancer cells. It may also be used as a sterol standard for calibration curve generation in liquid chromatography multiple reaction monitoring (LC-MRM) analysis.
Definition
ChEBI: Campesterol is a member of phytosterols, a 3beta-sterol, a 3beta-hydroxy-Delta(5)-steroid and a C28-steroid. It has a role as a mouse metabolite. It derives from a hydride of a campestane.
General Description
Campesterol is a plant sterol, which is an analog of cholesterol and a brassinosteroid (BR) precursor. The enzyme diminute/dwarf1 mediates the synthesis of campesterol from 24-methylenecholesterol. Campesterol possesses methyl group at C-24 position of the side chain in the cholesterol structure.
Biochem/physiol Actions
Campesterol is a phytosterol, primarily found in nuts, fruits, legumes and seeds. Though an analogue of cholesterol, it is poorly absorbed in humans and competitively inhibits the absorption of cholesterol. Campesterol decreases the transcription of genes involved in cholesterol metabolism in hepatocytes and enterocytes and has positive impact in treatment of cardiovascular disease.
Purification Methods
Campesterol is recrystallised twice from hexane and once from Me2CO. The benzoyl derivative has m 158-160o [] D 23 -8.6o (CHCl3), and the acetyl derivative has m 137138o (EtOH) and [] D 23 -35.1o (c 2.9, CHCl3) [Fernholz & MacPhillamy J Am Chem Soc 6 3 1155 1941]. [Beilstein 6 III 2680.]
CAMPESTEROL Preparation Products And Raw materials
Raw materials
Preparation Products
CAMPESTEROL Suppliers
- Tel
- +91-22-26355700
- Fax
- +91-22-26355701
- info@clearsynth.com
- Country
- India
- ProdList
- 9685
- Advantage
- 58
View Lastest Price from CAMPESTEROL manufacturers
- Product
- Campesterol 474-62-4
- Price
- US $70.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 10kg
- Release date
- 2020-06-13
- Product
- Campesterol 474-62-4
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2020-01-02
- Product
- Campesterol 474-62-4 474-62-4
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 tons
- Release date
- 2021-10-08