ChemicalBook > CAS DataBase List > 4,6-DIFLUOROPYRIMIDINE

4,6-DIFLUOROPYRIMIDINE

Product Name
4,6-DIFLUOROPYRIMIDINE
CAS No.
2802-62-2
Chemical Name
4,6-DIFLUOROPYRIMIDINE
Synonyms
4,6-DIFLUOROPYRIMIDINE;PyriMidine,4,6-difluoro-;Pyrimidine, 4,6-difluoro- (6CI,8CI,9CI)
CBNumber
CB9170184
Molecular Formula
C4H2F2N2
Formula Weight
116.07
MOL File
2802-62-2.mol
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4,6-DIFLUOROPYRIMIDINE Property

Boiling point:
125℃
Density 
1.376
Flash point:
29℃
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
-4.88±0.17(Predicted)
form 
liquid
color 
Clear, yellow
InChI
InChI=1S/C4H2F2N2/c5-3-1-4(6)8-2-7-3/h1-2H
InChIKey
MCLDVUCSDZGNRR-UHFFFAOYSA-N
SMILES
C1=NC(F)=CC(F)=N1
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38-41
Safety Statements 
26-36/37/39-39
HazardClass 
IRRITANT
HS Code 
2933599590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H226Flammable liquid and vapour

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
D448658
Product name
4,6-Difluoropyrimidine
Packaging
500mg
Price
$75
Updated
2021/12/16
Apolloscientific
Product number
PC3333
Product name
4,6-Difluoropyrimidine
Purity
95%
Packaging
5g
Price
$80
Updated
2021/12/16
Matrix Scientific
Product number
034743
Product name
4,6-Difluoropyrimidine
Purity
95%
Packaging
1g
Price
$24
Updated
2021/12/16
AK Scientific
Product number
2703AB
Product name
4,6-Difluoropyrimidine
Packaging
1g
Price
$25
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD77530
Product name
4,6-Difluoropyrimidine
Packaging
2g
Price
$40
Updated
2021/12/16
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4,6-DIFLUOROPYRIMIDINE Chemical Properties,Usage,Production

Synthesis

1193-21-1

2802-62-2

a) Preparation of 4,6-difluoropyrimidine (STR13): 4,6-dichloropyrimidine (223.5 g, 1.5 mol), potassium fluoride (279.6 g, 4.8 mol) and tetrabutylammonium bromide (6.0 g, 0.0186 mol) were dissolved in cyclobutanesulfone (1 L). The reaction mixture was heated at 180-190 °C for 3.5 h followed by distillation to afford the target product 4,6-difluoropyrimidine as a white liquid (115 g, 66% yield).

References

[1] Patent: US5977363, 1999, A
[2] Patent: US5977363, 1999, A
[3] Patent: EP794177, 1997, A1
[4] Patent: EP794177, 1997, A1
[5] Chemistry Letters, 1993, # 3, p. 509 - 512

4,6-DIFLUOROPYRIMIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4,6-DIFLUOROPYRIMIDINE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
4,6-Difluoropyrimidine 2802-62-2
Price
US $0.01-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 tons
Release date
2020-04-22
Career Henan Chemical Co
Product
4,6-DIFLUOROPYRIMIDINE 2802-62-2
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
JD 491
Release date
2019-09-01