5-Hydroxyisoquinoline

Product Name: 5-Hydroxyisoquinoline
CAS No.: 2439-04-5
Chemical Name: 5-Hydroxyisoquinoline
Synonyms: NSC 51787;5-ISOQUINOLINOL;ISOQUINOLIN-5-OL;Isoquinoline-5-ol;5-Hydroxyisoquinolne;5-Hydroxyisoquin din;5-HYDROXYISOQUINOLINE;5-Hydroxyisoquin dine;5-Hydroxyisoquinoline90%;5-Hydroxyisoquinoline>
CBNumber: CB9174379
Molecular Formula: C9H7NO
Formula Weight: 145.16
MOL File: 2439-04-5.mol

More

Less

5-Hydroxyisoquinoline Property

Melting point:: 213-215
Boiling point:: 264.27°C (rough estimate)
Density: 1.1555 (rough estimate)
refractive index: 1.4500 (estimate)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
pka: 8.53±0.40(Predicted)
form: Granular Powder
color: Beige
InChI: InChI=1S/C9H7NO/c11-9-3-1-2-7-6-10-5-4-8(7)9/h1-6,11H
InChIKey: CSNXUYRHPXGSJD-UHFFFAOYSA-N
SMILES: C1C2=C(C(O)=CC=C2)C=CN=1
CAS DataBase Reference: 2439-04-5(CAS DataBase Reference)

More

Less

Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-21/22
Safety Statements: 26-37/39-36/37/39-36
WGK Germany: 3
Hazard Note: Irritant
HS Code: 29334900

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: H33207
Product name: 5-Hydroxyisoquinoline
Purity: technical grade, 90%
Packaging: 5g
Price: $85
Updated: 2025/07/31

Sigma-Aldrich

Product number: H33207
Product name: 5-Hydroxyisoquinoline
Purity: technical grade, 90%
Packaging: 25g
Price: $436
Updated: 2023/06/20

TCI Chemical

Product number: H1259
Product name: 5-Hydroxyisoquinoline
Purity: >96.0%(GC)(T)
Packaging: 5g
Price: $198
Updated: 2025/07/31

TCI Chemical

Product number: H1259
Product name: 5-Hydroxyisoquinoline
Purity: >96.0%(GC)(T)
Packaging: 25g
Price: $698
Updated: 2025/07/31

TRC

Product number: H953260
Product name: 5-Hydroxyisoquinoline
Packaging: 100mg
Price: $50
Updated: 2021/12/16

More

Less

5-Hydroxyisoquinoline Chemical Properties,Usage,Production

Chemical Properties

beige granular powder

Uses

5-Hydroxyisoquinoline is a reagent used in the preparation of PARP inhibitor.

Synthesis

27655-40-9

2439-04-5

The general procedure for the synthesis of 5-hydroxyisoquinoline from 5-isoquinolinesulfonic acid is as follows: 23 g of 5-isoquinolinesulfonic acid is added to 400 ml of water, followed by 60 g of sodium hydroxide. The reaction mixture was heated to reflux and stirred continuously under this condition for 24 hours. Upon completion of the reaction, the mixture was cooled to room temperature and the pH was adjusted with dilute hydrochloric acid to 5. Then, ethyl acetate was added for extraction and the organic phase was separated and collected. The organic phase was concentrated and the resulting residue was purified by silica gel column chromatography to yield 16 g of 5-hydroxyisoquinoline.

References

[1] Acta Poloniae Pharmaceutica, 1994, vol. 51, # 6, p. 479 - 482
[2] Patent: CN107778231, 2018, A. Location in patent: Paragraph 0023; 0024

5-Hydroxyisoquinoline Preparation Products And Raw materials

Raw materials

FUMING SULFURIC ACID Isoquinoline Potassium hydroxide Sodium hydroxide Sulfuric acid

Preparation Products

More

Less

5-Hydroxyisoquinoline Suppliers

Americas 1 Belgium 1 Canada 1 China 127 Europe 1 Germany 3 India 3 Japan 2 Slovakia 1 Switzerland 1 United Kingdom 6 United States 25 Global 172

Changzhou Anchor Biological Technology Co., Ltd

Tel: 0519-85519868 18915088878
Fax: 0519-85512868
Email: sales@ankerbio.com
Country: China
ProdList: 261
Advantage: 58

Changzhou Xinda Biotechnology Co., Ltd

Tel: 0519-85519868 18915088878
Email: xiaoweng106108@163.com
Country: China
ProdList: 99
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Shijiazhuang Sdyano Fine Chemical Co., Ltd.

Tel: 0311-89250318 031166536426
Fax: 4000311741
Email: master@sjzsdyn.com
Country: China
ProdList: 2807
Advantage: 65

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9310
Advantage: 66

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9883
Advantage: 59

More

Less

View Lastest Price from 5-Hydroxyisoquinoline manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 5-Hydroxyisoquinoline 2439-04-5
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-04-07

Shaanxi Dideu Medichem Co. Ltd

Product: 5-Hydroxyisoquinoline 2439-04-5
Price: US $0.10/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 1000 tons
Release date: 2020-04-29

Honest Joy Holdings Limited

Product: 5-Hydroxyisoquinoline
Price: US $0.00/KG
Min. Order: 1KG
Purity: 97.7%
Supply Ability: 100 tons
Release date: 2022-02-18

2439-04-5, 5-HydroxyisoquinolineRelated Search:

HYDROXYAPATITE TYPE I 4-Hydroxybenzaldehyde Methylparaben Isoquinoline Glycolic acid 10-Hydroxycamptothecin Hydroxy silicone oil Chrysin 5,6,7,8-TETRAHYDROISOQUINOLINE 3-HYDROXYISOQUINOLINE N-Fmoc-D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid D-1,2,3,4-TETRAHYDRO-7-HYDROXYISOQUINOLINE-3-CARBOXYLIC ACID DIHYDRATE,D-1,2,3,4-TETRAHYDRO-7-HYDROXYISOQUINOLINE-3-CARBOXYLIC ACID HYDRATE FMOC-TIC-OH 6,7-DIMETHOXY-1,2,3,4-TETRAHYDROISOQUINOLINE-1-THIONE 1-BENZYL-6,7-DIMETHOXY-1,2,3,4-TETRAHYDROISOQUINOLINE HYDROCHLORIDE 4-BROMO-1-HYDROXYISOQUINOLINE 1,2,3,4-Tetrahydro-4-hydroxyisoquinoline-2-carboxamidine,3,4-Dihydro-4-hydroxyisoquinoline-2(1H)-carboxamidine Isocarbostyril

5-HYDROXYISOQUINOLINE

5-ISOQUINOLINOL

5-Hydroxyisoquinolne

ISOQUINOLIN-5-OL

5-HYDROXYISOQUINOLINE, TECH., 90%

5-Hydroxyisoquinoline,tech.90%

5-Hydroxyisoquinoline 90%

5-Hydroxyisoquinoline90%

5-Hydroxyisoquinoline,90%,tech.

Isoquinoline-5-ol

5-Hydroxyisoquinoline ,96%

5-Hydroxyisoquin din

5-isoquinolinol(SALTDATA: FREE)

5-Hydroxyisoquin dine

NSC 51787

5-Hydroxyisoquinoline, 90%, technical

Isoquinolin-5-ol, 5-Hydroxy-2-azanaphthalene

5-Hydroxyisoquinoline technical grade, 90%

5-Hydroxyisoquinoline&gt

5-Hydroxyisoquinoline ISO 9001：2015 REACH

2439-04-5

243-94-5

2435-04-5

196962

2439-4-5

196-96-2

2439-04-05

2349-04-5

Isoquinolines

Heterocyclic Building Blocks

Building Blocks

Quinolines

Heterocyclic Series

Aromatics

Intermediates & Fine Chemicals

Pharmaceuticals