ChemicalBook > CAS DataBase List > 3-Hydroxy-4-methoxycinnamic acid

3-Hydroxy-4-methoxycinnamic acid

Product Name
3-Hydroxy-4-methoxycinnamic acid
CAS No.
537-73-5
Chemical Name
3-Hydroxy-4-methoxycinnamic acid
Synonyms
ISOFERULIC ACID;(E)-3-(3-hydroxy-4-Methoxyphenyl)acrylic acid;Isoferulic;HESPERETIC ACID;Hesperetate;Isoferulate;Isoferulic Aci;HESPERETINIC ACID;AKOS BBS-00006960;Hesperitinic acid
CBNumber
CB9178579
Molecular Formula
C10H10O4
Formula Weight
194.18
MOL File
537-73-5.mol
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3-Hydroxy-4-methoxycinnamic acid Property

Melting point:
230 °C (dec.)(lit.)
Boiling point:
250.62°C (rough estimate)
Density 
1.0583 (rough estimate)
refractive index 
1.5168 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Soluble in ethanol and methanol.
pka
4.53±0.10(Predicted)
form 
Solid
color 
Pale Yellow
BRN 
2212760
LogP
0.788 (est)
CAS DataBase Reference
537-73-5(CAS DataBase Reference)
NIST Chemistry Reference
Cinnamic acid, 3-hydroxy-4-methoxy-(537-73-5)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39-24/25
WGK Germany 
2
RTECS 
UD3365400
Hazard Note 
Irritant
HS Code 
29189090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
103012
Product name
3-Hydroxy-4-methoxycinnamic acid, predominantly trans
Purity
97%
Packaging
1g
Price
$41.5
Updated
2024/03/01
Sigma-Aldrich
Product number
103012
Product name
3-Hydroxy-4-methoxycinnamic acid, predominantly trans
Purity
97%
Packaging
5g
Price
$198
Updated
2024/03/01
TCI Chemical
Product number
H0524
Product name
3-Hydroxy-4-methoxycinnamic Acid
Purity
>98.0%(T)(HPLC)
Packaging
1g
Price
$56
Updated
2024/03/01
TCI Chemical
Product number
H0524
Product name
3-Hydroxy-4-methoxycinnamic Acid
Purity
>98.0%(T)(HPLC)
Packaging
5g
Price
$220
Updated
2024/03/01
Alfa Aesar
Product number
A10482
Product name
3-Hydroxy-4-methoxycinnamic acid, predominantly trans, 98+%
Packaging
1g
Price
$33.65
Updated
2024/03/01
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3-Hydroxy-4-methoxycinnamic acid Chemical Properties,Usage,Production

Chemical Properties

Off-White Crystalline Solid

Uses

3-Hydroxy-4-methoxycinnamic Acid (Isoferulic acid) is a hypoglycemic agent.

Uses

3-Hydroxy-4-methoxycinnamic acid exhibits hypoglycemic properties.

Uses

3-Hydroxy-4-methoxycinnamic acid was used in the synthesis of tranilast and various tranilast analogs (cinnamoyl anthranilates) by genetically engineered Saccharomyces cerevisiae yeast strain. It was also used in the synthesis of glycoside compounds by undergoing glycosidation.

Definition

ChEBI: A ferulic acid consisting of trans-cinnamic acid bearing methoxy and hydroxy substituents at positions 4 and 3 respectively on the phenyl ring.

General Description

3-Hydroxy-4-methoxycinnamic acid, predominantly trans is available as white crystals. 3-Hydroxy-4-methoxycinnamic acid is isolated from the aerial part of Artemisia capillaris, Chinese medicinal plant. It is a component of chinese herbal medicine used for a pain killer and stomachic. It is an efficient acetylcholine inhibitor. 3-Hydroxy-4-methoxycinnamic acid is bioactive metabolite of Spilanthes acmella Murr. It increases the resistance of low-density lipoprotein (LDL) to oxidation.

3-Hydroxy-4-methoxycinnamic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Hydroxy-4-methoxycinnamic acid Suppliers

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View Lastest Price from 3-Hydroxy-4-methoxycinnamic acid manufacturers

Hebei Dangtong Import and export Co LTD
Product
3-Hydroxy-4-methoxycinnamic acid 537-73-5
Price
US $456.00-440.00/kilograms
Min. Order
10kilograms
Purity
99%
Supply Ability
100tons
Release date
2023-02-16
Shaanxi Dideu Medichem Co. Ltd
Product
3-Hydroxy-4-MethoxycinnaMic Acid 537-73-5
Price
US $1.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50 tons
Release date
2020-01-20
Hebei Duling International Trade Co. LTD
Product
3-Hydroxy-4-methoxycinnamic acid 537-73-5
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000 Ton
Release date
2022-10-11

537-73-5, 3-Hydroxy-4-methoxycinnamic acidRelated Search:

trans-Cinnamic acid 3-Hydroxycinnamic acid 4-Hydroxycinnamic acid 4-Methoxycinnamic acid CHLOROPHOSPHONAZO III N-BUTYL CINNAMATE Methyl cinnamate alpha-Methylcinnamic acid Ethyl cinnamate 3,4-Dimethoxycinnamonitrile HYDROXYCINNAMIC ACID 3,4-(Methylenedioxy)cinnamic acid 2-BROMO-4,5-METHYLENEDIOXYCINNAMIC ACID 3,4,5-TRIMETHOXYCINNAMIC ACID ETHYL ESTER 4,5-DIMETHOXY-2-NITROCINNAMIC ACID trans-2,3,4-Trimethoxycinnamic acid 2-BROMO-4,5-DIMETHOXYCINNAMIC ACID trans-2,4,5-Trimethoxycinnamic acid

  • ISOFERULIC ACID
  • HESPERETINIC ACID
  • HESPERETIC ACID
  • 3-HYDROXY-4-METHOXYCINNAMIC ACID
  • AKOS BBS-00006960
  • (2E)-3-(3-HYDROXY-4-METHOXYPHENYL)ACRYLIC ACID
  • (2E)-3-(3-Hydroxy-4-methoxyphenyl)-2-propenoic acid
  • 2-Propenoic acid, 3-(3-hydroxy-4-methoxyphenyl)-
  • 3-(3-hydroxy-4-methoxyphenyl)-2-propenoicaci
  • 3-hydroxy-4-methoxy-cinnamicaci
  • RARECHEM BK HW 0093
  • trans-3-Hydroxy-4-methoxycinnamic acid
  • 3-HYDROXY-4-METHOXYCINNAMIC ACID, 97%, P REDOMINANTLY TRANS
  • 4-Methoxy-3-hydroxycinnamic acid
  • 3-(3-Hydroxy-4-methoxy-phenyl)-acrylic Aci
  • Isoferulic
  • 3-hydroxy-4-methoxycinnamic acid, predominantly trans
  • 3-(3-hydroxy-4-methoxy-phenyl)prop-2-enoic acid
  • ISOFERULIC ACID(P)
  • 3-(3-Hydroxy-4-methoxyphenyl)acrylic Acid
  • 3-Hydroxy-4-methoxycinnamic acid, 98+%
  • Isoferulic acid，Hesperetic acid
  • 3-Hydroxy-4-methoxycinnamic acid, predominantly trans, 98+%
  • 3-[(2Z)-2-[(Z)-2-methyl-3-[3-(3-sulfopropyl)-1,3-benzoselenazol-3-ium-2-yl]prop-2-enylidene]-1,3-benzoselenazol-3-yl]-1-propanesulfonate
  • Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid)
  • 3-(3-Hydroxy-4-methoxyphenyl)-2-propenoic acid
  • 3-(3-Hydroxy-4-methoxyphenyl)propenoic acid
  • Caffeic acid 4-methyl ether
  • Hesperitinic acid
  • HESPERETIC ACID(SH)
  • 3-Hydroxy-4-methoxyciamic acid
  • 3-Hydroxy-4-MethoxycinnaMic Acid (Isoferulic acid)
  • Hesperetic Acid Isoferulic Acid
  • 3-HYDROXY-4-METHOXYCINNAMIC ACID FOR SYN
  • Extra CAS No: 24276-84-4, 25522-33-2
  • (E)-3-(3-hydroxy-4-Methoxyphenyl)acrylic acid
  • Isoferulic Aci
  • 3-Hydroxy-4-MethoxycinnaMic acid, predoMinantly trans 97%
  • Isoferulic acid, 98%, 98%
  • hydrogen 3-[2-{2-methyl-3-[3-(3-sulfonatopropyl)-1,3-benzoselenazol-3-ium-2-yl]prop-2-en-1-ylidene}-1,3-benzoselenazol-3(2h)-yl]propane-1-sulfonate
  • 3-Hydroxy-4-methoxycinnamic acid for synthesis
  • 3-Hydroxy-4-methoxycinnamic
  • 3-Hydroxy-4-methoxycinnamicAcid&gt
  • 3-(3-Hydroxy-4-methoxyphenyl)-2-(E)-propenoic Acid
  • Hesperetate
  • Isoferulate
  • 3-Hydroxy-4-methoxycinnamic acid USP/EP/BP
  • 5-dihydroxybenzoate
  • (2E)-3-(3-hydroxy-4-methoxyphenyl)prop-2-enoic acid
  • 537-73-5
  • HOOCCHCHC6H3OHOCH3
  • HOC6H3OCH3CHCHCO2H
  • CARBOXYLIC ACID
  • Organic Building Blocks
  • Building Blocks
  • Carboxylic Acids
  • Carbonyl Compounds
  • C10