ChemicalBook > CAS DataBase List > Stanolone

Stanolone

Product Name
Stanolone
CAS No.
521-18-6
Chemical Name
Stanolone
Synonyms
DHT;DIHYDROTESTOSTERONE;ANDROSTANOLONE;5α-Dihydrotestosterone;5α-DHT;Anaboleen;Andractim;4-dihydrotestosterone;5ALPHA-DIHYDROTESTOSTERONE;5ALPHA-ANDROSTAN-17BETA-OL-3-ONE
CBNumber
CB9181225
Molecular Formula
C19H30O2
Formula Weight
290.45
MOL File
521-18-6.mol
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Stanolone Property

Melting point:
178-183 °C
alpha 
27 º
Boiling point:
372.52°C (rough estimate)
Density 
1.0320 (rough estimate)
refractive index 
1.4709 (estimate)
Flash point:
9℃
storage temp. 
2-8°C
solubility 
Acetonitrile: 1 mg/ml; Ethanol: 1 mg/ml; Methanol: 1 mg/ml
pka
15.08±0.60(Predicted)
Water Solubility 
344.3g/L(temperature not stated)
Merck 
13,8872
BRN 
2056371
InChIKey
NVKAWKQGWWIWPM-ABEVXSGRSA-N
CAS DataBase Reference
521-18-6(CAS DataBase Reference)
NIST Chemistry Reference
Stanolone(521-18-6)
EPA Substance Registry System
Androstan-3-one, 17-hydroxy-, (5.alpha.,17.beta.)- (521-18-6)
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Safety

Hazard Codes 
Xn,T,F
Risk Statements 
61-40-39/23/24/25-23/24/25-11
Safety Statements 
53-36/37/39-45-36/37-16
RIDADR 
UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 
3
RTECS 
BV8052000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H351Suspected of causing cancer

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR9196
Product name
5α-Androstan-17β-ol-3-one
Purity
certified reference material, TraceCERT?
Packaging
100MG
Price
$691
Updated
2024/03/01
Sigma-Aldrich
Product number
D-073
Product name
5α-Dihydrotestosterone (DHT) solution
Purity
1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant?
Packaging
1mL
Price
$142
Updated
2024/03/01
Sigma-Aldrich
Product number
A8380
Product name
5α-Androstan-17β-ol-3-one
Purity
≥97.5%
Packaging
1g
Price
$86
Updated
2024/03/01
Sigma-Aldrich
Product number
A8380
Product name
5α-Androstan-17β-ol-3-one
Purity
≥97.5%
Packaging
10g
Price
$515
Updated
2024/03/01
Cayman Chemical
Product number
15874
Product name
Dihydrotestosterone
Purity
≥97%
Packaging
25mg
Price
$275
Updated
2024/03/01
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Stanolone Chemical Properties,Usage,Production

Description

Stanolone is well known as dihydrotestosterone (DHT), which is an endogenous androgen sex steroid and hormone. It is an agonist of the androgen receptor (AR). It plays important physiological role in sexual differentiation, maturation of the penis and scrotum, hair, sebum production and development and maintenance of the prostate gland and seminal vesicles. It is mainly used for the treatment of male hypogonadism, androgen deficiency of severe illness, androgen deficiency of ageing and microphallus in infancy.

Chemical Properties

White Crystalline Solid

Originator

Neodrol,Pfizer,US,1953

Uses

Stanolone is a potent androgenic metabolite of testosterone that It is Controlled substance. It was created for the treatment of muscle wasting disease, and osteoporosis. It is a powerful anabolic steroid, which is similar to the body's naturally produced Dihydrotestosterone. Dihydrotestosterone (DHT) is generated by a 5-alpha reduction of testosterone. Unlike testosterone, DHT cannot be aromatized to estradiol therefore DHT is considered a pure androgenic steroid.

Definition

ChEBI: Stanolone is a 17beta-hydroxy steroid that is testosterone in which the 4,5 double bond has been reduced to a single bond with alpha-configuration at position 5. It has a role as an androgen, a human metabolite, a Daphnia magna metabolite and a mouse metabolite. It is a 17beta-hydroxy steroid, a 17beta-hydroxyandrostan-3-one and a 3-oxo-5alpha-steroid. It derives from a hydride of a 5alpha-androstane.

Manufacturing Process

A solution of 1.0 g of 3,17-androstandione in 50 ml of methanol and containing 1 g of selenium dioxide, was allowed to remain in an ice-chest overnight. The formed 3,3-dimethoxyandrostan-17-one was not separated. 1 g of solid potassium hydroxide and 2.5 g of sodium borohydride in 2.5 ml of water were added and the mixture allowed to react at room temperature for 24 hours. The solution was then poured into a large excess of water, extracted with methylene chloride, the organic layer dried and evaporated to a residue. The residue was dissolved in ether, and a small amount of selenium removed by filtration. The ether was boiled off and the organic material dissolved in 100 ml of boiling acetone. 25 ml of diluted hydrochloric acid were added, the solution boiled for 5 minutes and then allowed to cool. Upon crystallization, 0.85 g of androstan-17β-ol-3-one was obtained, melting point 175°C to 178°C.

Therapeutic Function

Androgen

General Description

Dihydrotestosterone (Item No. 15874) is an analytical reference standard categorized as an anabolic androgenic steroid. Anabolic steroids, including dihydrotestosterone, have been used to enhance physical performance in athletes. Dihydrotestosterone is regulated as a Schedule III compound in the United States. This product is intended for research and forensic applications.

Side effects

In rare cases, serious and even fatal cases of liver problems have developed during treatment with stanozolol. Contact your doctor immediately if you experience abdominal pain, light-colored stools, dark-colored urine, unusual fatigue, nausea or vomiting, or yellowing of the skin or eyes. These may be early signs of liver problems.
Serious side effects: an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); swelling of the arms or legs (especially ankles); frequent or persistent erections, or breast tenderness or enlargement (male patients); or voice changes (hoarseness, deepening), hair loss, facial hair growth, clitoral enlargement, or menstrual irregularities (female patients).
Common stanozolol side effects may include: new or worsening acne; difficulty sleeping; headache; or changes in sexual desire.

References

https://en.wikipedia.org/wiki/Dihydrotestosterone#Medical_use
Swerdloff, R. S., and C. Wang. "Dihydrotestosterone: a rationale for its use as a non-aromatizable androgen replacement therapeutic agent."Baillieres Clin Endocrinol Metab 12.3(1998):501.

Stanolone Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Stanolone manufacturers

hebei hongtan Biotechnology Co., Ltd
Product
stanolone 521-18-6
Price
US $130.00-110.00/kg
Min. Order
1kg
Purity
99.9%
Supply Ability
20
Release date
2024-05-11
Wuhan Cell Pharmaceutical Co., Ltd
Product
Androstanolone;Stanolone;dihydrotestosterone;DHT 521-18-6
Price
US $10.00-300.00/g
Min. Order
1g
Purity
99.99%
Supply Ability
500kg
Release date
2023-10-09
CONTIDE BIOTECH CO.,LTD
Product
Stanolone (androstanolone) 521-18-6
Price
US $0.00/G
Min. Order
1G
Purity
99%
Supply Ability
20
Release date
2024-04-12

521-18-6, StanoloneRelated Search:


  • (5S,8R,9S,10S,13S,14S,17S)-17-Hydroxy-10,13-dimethyltetradecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one
  • 5α-androstan-17β-ol-3-one solution,100ppm
  • (8R,9S,10S,13S,14S)-17-hydroxy-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one
  • (5-alpha,17-beta)-17-hydroxyandrostan-3-one
  • (5alpha,17beta)-17-Hydroxy-androstan-3-one
  • 17beta-Hydroxy-3-androstanone
  • 17-beta-hydroxy-5-alpha-androstan-3-on
  • 17-hydroxy-,(5-alpha,17-beta)-androstan-3-on
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  • 5A-Androstan-3-on-17B-ol
  • 5a-Androstan-3-one, 17beta-hydroxy-
  • 5alpha,17beta-Hydroxyandrostan-3-one
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  • DIHYDROTESTOSTERONE
  • DHT
  • 5α-Androstan-17β-ol-3-one,17β-Hydroxy-5α-androstan-3-one, 4,5α-Dihydrotestosterone, Androstanolone, Stanolone
  • 5α-Dihydrotestosterone (DHT)
  • 5α-Dihydrotestosterone
  • Dihydrotestosterone (CIII)
  • Stanolone/Androstanolone
  • 5alpha-Androstan-17beta-ol-3-one 5alpha-Dihydrotestosterone DHT
  • Stanolone(Androstanolone、DHT)
  • ANDROSTANOLONE(RG)
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  • (5S,8R,9R,10S,13S,14R,17S)-17-hydroxy-10,13-diMethyltetradecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one
  • Androstan-3-one, 17-hydroxy-, (5q,17b)-
  • Androstan-3-one,17-hydroxy-, (5a,17b)-
  • 5α?DHT solution
  • 5α-Dihydrotestosterone (DHT) solution
  • 5α-Dihydrotestosterone solution
  • 4,5 alpha-Dihydrotestosterone (Androstanolone)
  • high purity 521-18-6 anabolic steroid Stanolone Androstanolone CAS NO.521-18-6
  • Testosterone Impurity 6(Testosterone EP Impurity F)
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  • 5A-ANDROSTAN-17B-OL-3-ONE
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  • 5ALPHA-ANDROSTAN-17BETA-OL-3-ONE
  • 5-ALPHA-ANDROSTANOLONE
  • 5ALPHA-DIHYDROTESTOSTERONE
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