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Nandrolone Decanoate

Product Name
Nandrolone Decanoate
CAS No.
360-70-3
Chemical Name
Nandrolone Decanoate
Synonyms
DECADURABOLIN;Anabolicum;Nandrolone Deconate;Nandrolone Decanoate (DECA);19-NORTESTOSTERONE 17-DECANOATE;retabolil;Decanofort;Extraboline;Deca-Hybolin;deca-durabol
CBNumber
CB0396051
Molecular Formula
C28H44O3
Formula Weight
428.65
MOL File
360-70-3.mol
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Nandrolone Decanoate Property

Melting point:
33-37°C
Boiling point:
483.46°C (rough estimate)
alpha 
32 º
Density 
1.0406 (rough estimate)
refractive index 
1.4700 (estimate)
storage temp. 
2-8°C
solubility 
45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.8 mg/mL
form 
powder
color 
white to light yellow
Water Solubility 
664ug/L(37 ºC)
InChI
InChI=1/C28H44O3/c1-3-4-5-6-7-8-9-10-27(30)31-26-16-15-25-24-13-11-20-19-21(29)12-14-22(20)23(24)17-18-28(25,26)2/h19,22-26H,3-18H2,1-2H3/t22-,23+,24+,25-,26-,28-/s3
InChIKey
JKWKMORAXJQQSR-MOPIKTETSA-N
SMILES
[C@@]12([H])CC[C@H](OC(=O)CCCCCCCCC)[C@@]1(C)CC[C@]1([H])[C@@]3([H])CCC(=O)C=C3CC[C@@]21[H] |&1:0,4,17,21,23,33,r|
CAS DataBase Reference
360-70-3
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Safety

Hazard Codes 
Xn
Risk Statements 
40
Safety Statements 
22-36
WGK Germany 
3
RTECS 
KG7967000
HS Code 
2937290000
Toxicity
LD50 intraperitoneal in mouse: > 566mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H351Suspected of causing cancer

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
BP425
Product name
Nandrolone decanoate
Purity
British Pharmacopoeia (BP) Reference Standard
Packaging
50MG
Price
$266
Updated
2024/03/01
Sigma-Aldrich
Product number
1455000
Product name
Nandrolone decanoate
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
250mg
Price
$581
Updated
2024/03/01
Biosynth Carbosynth
Product number
FN170079
Product name
Nandrolone decanoate
Packaging
250g
Price
$650
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0003493
Product name
NANDROLONE DECANOATE
Purity
95.00%
Packaging
100MG
Price
$750.75
Updated
2021/12/16
Biosynth Carbosynth
Product number
FN170079
Product name
Nandrolone decanoate
Packaging
100g
Price
$340
Updated
2021/12/16
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Nandrolone Decanoate Chemical Properties,Usage,Production

Description

Nandrolone decanoate, also known as nandrolone caprinate, is an alkylated anabolic steroid indicated in the management of anemia of renal insufficiency and as an adjunct therapy in the treatment of senile and postmenopausal osteoporosis. The process for creating esters of [nandrolone] was patented in Spain in 1959 and in 1960, it was described as having a long duration of action and strong anabolic effect compared to nandrolone and other esters. Nandrolone decanoate was granted FDA approval on 5 October 1962.

Chemical Properties

White or almost white, crystalline powder.

Originator

Deca-Durabolin,Organon,US,1962

Uses

Nandrolone Decanoate is an anabolic steroid. Nandrolone decanoate is used in the treatment of osteoporosis in postmenopausal women. Nandrolone Decanoate is also used for some aplastic anemias. Control led Substance.

Definition

ChEBI: Nandrolone decanoate is a steroid ester.

Manufacturing Process

1 gram of 19-nortestosterone is dissolved in 3 ml of dry pyridine, after which the resulting solution is cooled to -20°C. A solution of 1.0 gram of decanoic acid chloride in 3 ml of dry benzene is added to the cooled solution. The mixture is maintained at -15°C for 16 hours and then poured into ice water. The aqueous liquid is extracted with benzene, the benzene solution is washed with respectively 1 N sodium hydroxide solution, 2 N hydrochloric acid and with water until neutral reaction.
Then the solution is dried on sodium sulfate, filtered, and evaporated to dryness. The residue, 1.63 grams is dissolved in hexane, this solution is filtered over 30 grams of neutral aluminum oxide, and evaporated to dryness. On paper chromatographic investigation it turned out that the obtained 19- nortestosterone 17-decanoate which at room temperature is an oil consists of a single compound, according to US Patent 2,998,423.

brand name

Durabolin (Organon);Abolon;Activin;Anabolin la 100;Anador;Anadur;Analone-50;Androlone d 100;Androlone d 50;Decabolin;Deca-durabolin decanoate;Deca-noralone;Docabolin;Fherbolico;Fortabolin;Hybolin-decanoate;Iebolan;Kabolin;Keratyl;Methybol-depot;Nandrolone decanoate;Nordecon;Stenabolin;Sterobolin;Turinabol-depot.

Therapeutic Function

Anabolic

World Health Organization (WHO)

Nandrolone decanoate, an anabolic steroid, was introduced in 1962. In 1982, low dosage preparations were prohibited in Bangladesh due to inadmissible promotion of products containing anabolic steroids for malnourished children. Higher dosage preparations of nandrolone decanoate remain available in many countries, including Bangladesh, for several highly specific but limited indications that apply to patients with chronic debilitating and emaciating diseases, particularly associated with neoplasia and some types of aplastic anaemia.

General Description

Nandrolone decanoate,17β-hydroxyestr-4-en-3-one 17-decanoate, has been used inthe management of certain anemias, but the availability oferythropoietin has greatly reduced this use.

Biochem/physiol Actions

Compared to testosterone propionate, nandrolone decanoate is considered to have strong anabolic effects but weak androgenic effects (potency ratios of 3.29–4.92 and 0.31–0.41).  In particular, nandrolone esters are thought to have the highest ratio of anabolic to androgenic effects of any AAS. The low androgenicity of nandrolone decanoate is thought to be due to the fact that nandrolone is inactivated by 5α-reductase via transformation into the low-affinity androgen receptor (AR) ligand 5α-dihydronandrolone. This is thought to result in a lower incidence and magnitude of side effects.Nandrolone decanoate (ND) injection has been classified as a Schedule III controlled substance under the Anabolic Steroids Control Act of 1990. Due to serious health risks, the nonmedical use of AASs is banned by most sports organizations[1].    

Side effects

There are many effects of this drug on the human body, and the studies of its side effects can be divided into the following: categories endocrine, cardiovascular, skin, psychiatric, musculoskeletal, excretory, and gastrointestinal disorders.

The most common side effects were: endocrine disorders (virilization, gynecomastia, hormonal disorders, cholesterol and lipid disorders, genital and infertility issues); cardiovascular disorders (vascular damage, coagulation disorders, arteriosus hypertension); skin disorders (pricking, acne, skin spots); psychiatric disorders (aggressiveness, mood disorders, sleep disorders, anxiety); musculoskeletal disorders (tendon ruptures); excretory disorders (organ damage); gastrointestinal disorders (organ damage and liver adenomas); neurological disorders (seizures); immune disorders (chronic infection relapse; respiratory disorders (sleep apnea syndrome); genetic disorders (genetic damage)[1].

Safety Profile

Experimental reproductiveeffects. When heated to decomposition it emits acridsmoke and irritating fumes.

Veterinary Drugs and Treatments

The principle use of nandrolone in veterinary medicine has been to stimulate erythropoiesis in patients with certain anemias (e.g., secondary to renal failure, aplastic anemias). It has also been suggested for use as an appetite stimulant.

Nandrolone Decanoate Preparation Products And Raw materials

Raw materials

Preparation Products

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Nandrolone Decanoate Suppliers

Guangzhou Xinyanze Biotechnology Co., LTD
Tel
18120340186
Email
3239311947@qq.com
Country
China
ProdList
377
Advantage
58
Hunan Fengdu Biotechnology Co., Ltd
Tel
13533334465 13533334465
Email
85382039@qq.com
Country
China
ProdList
115
Advantage
58
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3576
Advantage
66
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10194
Advantage
62
LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2127
Advantage
70
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42982
Advantage
64
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15421
Advantage
60
China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Country
China
ProdList
5700
Advantage
66
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8849
Advantage
52
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14443
Advantage
57
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View Lastest Price from Nandrolone Decanoate manufacturers

Wuhan Cell Pharmaceutical Co., Ltd
Product
Nandrolone Decanoate 360-70-3
Price
US $900.00/kg
Min. Order
1kg
Purity
99.99%
Supply Ability
2 tons
Release date
2023-10-09
hebei hongtan Biotechnology Co., Ltd
Product
NANDROLONE DECANOATE 360-70-3
Price
US $60.00-40.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20
Release date
2024-05-11
Apeloa production Co.,Limited
Product
Nandrolone decanoate 360-70-3
Price
US $1.00/g
Min. Order
1g
Purity
98%
Supply Ability
1000
Release date
2024-05-22

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