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Cyclohexyldiphenylphosphine

Product Name
Cyclohexyldiphenylphosphine
CAS No.
6372-42-5
Chemical Name
Cyclohexyldiphenylphosphine
Synonyms
DIPHENYLCYCLOHEXYLPHOSPHINE;whitextl;CYCLOHEXYLDI;Phosphine, cycL;Cyclohexyldiphenylphospine;Cyclohexyldihenylphosphine;CYCLOHEXYLDIPHENYLPHOSPHINE;cyclohexyldiphenyl-phosphin;DIPHENYLPHOSPHINOCYCLOHEXANE;Cyclohexyl-di(phenyl)phosphane
CBNumber
CB9196324
Molecular Formula
C18H21P
Formula Weight
268.33
MOL File
6372-42-5.mol
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Cyclohexyldiphenylphosphine Property

Melting point:
58-62 °C(lit.)
Boiling point:
374.0±11.0 °C(Predicted)
Flash point:
>230 °F
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
form 
Powder
color 
White
Water Solubility 
insoluble
Sensitive 
Air Sensitive
InChI
InChI=1S/C18H21P/c1-4-10-16(11-5-1)19(17-12-6-2-7-13-17)18-14-8-3-9-15-18/h1-2,4-7,10-13,18H,3,8-9,14-15H2
InChIKey
ZXKWUYWWVSKKQZ-UHFFFAOYSA-N
SMILES
P(C1CCCCC1)(C1=CC=CC=C1)C1=CC=CC=C1
CAS DataBase Reference
6372-42-5(CAS DataBase Reference)
EPA Substance Registry System
Phosphine, cyclohexyldiphenyl- (6372-42-5)
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Safety

Risk Statements 
36/37/38
Safety Statements 
24/25
WGK Germany 
3
RTECS 
SY8387500
TSCA 
No
HS Code 
29319090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
510742
Product name
Cyclohexyldiphenylphosphine
Packaging
5g
Price
$122
Updated
2025/07/31
TCI Chemical
Product number
C1429
Product name
Cyclohexyldiphenylphosphine
Purity
>97.0%(GC)
Packaging
5g
Price
$68
Updated
2025/07/31
TCI Chemical
Product number
C1429
Product name
Cyclohexyldiphenylphosphine
Purity
>97.0%(GC)
Packaging
25g
Price
$231
Updated
2025/07/31
Strem Chemicals
Product number
15-0900
Product name
Cyclohexyldiphenylphosphine, 98%
Packaging
1g
Price
$46
Updated
2024/03/01
Strem Chemicals
Product number
15-0900
Product name
Cyclohexyldiphenylphosphine, 98%
Packaging
5g
Price
$170
Updated
2024/03/01
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Cyclohexyldiphenylphosphine Chemical Properties,Usage,Production

Description

Cyclohexyldiphenylphosphine is a chemical compound commonly used as a ligand in coordination chemistry and organometallic synthesis. It acts as a stabilizing agent and facilitates various catalytic reactions. This compound finds applications in pharmaceuticals, fine chemicals, and materials science industries. Cyclohexyldiphenylphosphine should be handled with caution as it may cause skin and eye irritation. It should be stored in a cool, well-ventilated area away from heat sources or open flames. Proper personal protective equipment (PPE) should be worn when handling this compound. Not for human consumption. Such as Silver(I) phosphine complexes were synthesized by a reaction of AgNO3, AgCl, and AgBr with cyclohexyl diphenylphosphine to produce 1:1, 1:2, or 1:3 molar ratios of new silver complexes[1].

Chemical Properties

white to light yellow crystal powde

Uses

suzuki reaction

Uses

Cyclohexyldiphenylphosphine is used as ligand in coupling reaction. It is also used as a medical intermediate.

Reactions

Cyclohexyldiphenylphosphine can undergo complexation reactions with common transition metals and can be used to catalyze a variety of organic transformation reactions including Suzuki coupling reactions and metal-catalyzed Michael addition reactions.

reaction suitability

reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: ligand
reaction type: Cross Couplings

References

[1] Naganagowda, Gadada et al. “Synthesis, crystal structure and spectral studies of silver(I) cyclohexyldiphenylphosphine complexes: towards the biological evaluation on malignant and non-malignant cells.” Journal of Coordination Chemistry 21 1 (2023): 0.

Cyclohexyldiphenylphosphine Preparation Products And Raw materials

Raw materials

Preparation Products

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Cyclohexyldiphenylphosphine Suppliers

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View Lastest Price from Cyclohexyldiphenylphosphine manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Cyclohexyldiphenylphosphine 6372-42-5
Price
US $0.00/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
100kg/month
Release date
2021-07-27
Henan Research New Materials Co., Ltd.
Product
Cyclohexyldiphenylphosphine 6372-42-5
Price
US $0.00/Kg
Min. Order
1Kg
Purity
98%
Supply Ability
100kg
Release date
2025-04-12
XINXIANG RUNYU MATERIAL CO., LTD.
Product
Cyclohexyldiphenylphosphine 6372-42-5
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
500kg
Release date
2023-07-27

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