3-Nitrosalicylaldehyde
- Product Name
- 3-Nitrosalicylaldehyde
- CAS No.
- 5274-70-4
- Chemical Name
- 3-Nitrosalicylaldehyde
- Synonyms
- 2-HYDROXY-3-NITROBENZALDEHYDE;NSC 38026;AKOS B029850;3-nitrosalicaldehyde;3-NITROSALICYLALDEHYDE;LABOTEST-BB LT00939229;2-formyl-6-nitrophenolate;3-Nitrosalicylaldehyde>salicylaldehyde, 3-nitro-;3-Nitrosalicylaldehyde,98%
- CBNumber
- CB9199158
- Molecular Formula
- C7H5NO4
- Formula Weight
- 167.12
- MOL File
- 5274-70-4.mol
3-Nitrosalicylaldehyde Property
- Melting point:
- 105-109 °C(lit.)
- Boiling point:
- 295.67°C (rough estimate)
- Density
- 1.5216 (rough estimate)
- refractive index
- 1.6280 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- form
- Crystalline Powder
- pka
- 5.07±0.24(Predicted)
- color
- Yellow to brown
- Water Solubility
- slightly soluble
- Sensitive
- Air Sensitive
- CAS DataBase Reference
- 5274-70-4(CAS DataBase Reference)
- NIST Chemistry Reference
- Benzaldehyde, 2-hydroxy-3-nitro-(5274-70-4)
- EPA Substance Registry System
- Benzaldehyde, 2-hydroxy-3-nitro- (5274-70-4)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-22-20/21/22
- Safety Statements
- 26-36-36/37/39
- WGK Germany
- 3
- TSCA
- Yes
- HS Code
- 29130000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 527424
- Product name
- 2-Hydroxy-3-nitrobenzaldehyde
- Purity
- 98%
- Packaging
- 1g
- Price
- $35.4
- Updated
- 2024/03/01
- Product number
- 527424
- Product name
- 2-Hydroxy-3-nitrobenzaldehyde
- Purity
- 98%
- Packaging
- 5g
- Price
- $53.5
- Updated
- 2024/03/01
- Product number
- N0823
- Product name
- 3-Nitrosalicylaldehyde
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $71
- Updated
- 2025/07/31
- Product number
- N0823
- Product name
- 3-Nitrosalicylaldehyde
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $192
- Updated
- 2025/07/31
- Product number
- H949860
- Product name
- 2-Hydroxy-3-nitrobenzaldehyde
- Packaging
- 250mg
- Price
- $250
- Updated
- 2021/12/16
3-Nitrosalicylaldehyde Chemical Properties,Usage,Production
Chemical Properties
yellow to brown crystalline powder
Uses
2-Hydroxy-3-nitrobenzaldehyde may be used in the synthesis of 5-acetyl-4-aryl-6-methyl-1,2,3,4-tetrahydro pyrimidine.
General Description
2-Hydroxy-3-nitrobenzaldehyde can be extracted from the leaves of Actephila merrilliana. Its molecule is planar. On reaction with dapsone, it affords a colorless solution.
Synthesis
90-02-8
5274-70-4
GENERAL METHOD: Salicylaldehyde (10 mmol) was mixed with urea nitrate (10 mmol) in acetonitrile-water solvent mixture (95:5, 5 ml, v/v) in a 25 ml round bottom flask. The reaction mixture was placed in a Milestone Start SYNTH microwave reactor and heated at 80°C for 40-50 min. Upon completion of the reaction, the reaction mixture was cooled to room temperature, quenched with water and extracted with dichloromethane. The organic phase was concentrated under reduced pressure and the residue was purified by silica gel column chromatography to afford the target product 3-nitrosalicylaldehyde. In all experiments, o-nitrosalicylaldehyde was selectively generated and no para-nitro-substituted by-products were detected. The resulting compounds were characterized by 1H NMR, 13C NMR, melting point determination (for solid samples), GC-MS analysis and comparison with standards.
References
[1] Chinese Chemical Letters, 2010, vol. 21, # 4, p. 403 - 406
[2] Synthetic Communications, 2011, vol. 41, # 20, p. 2985 - 2992
[3] Tetrahedron Letters, 2014, vol. 55, # 7, p. 1320 - 1322
[4] Patent: WO2012/92880, 2012, A1. Location in patent: Page/Page column 57-58
[5] Tetrahedron, 1969, vol. 25, p. 3251 - 3266
3-Nitrosalicylaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
3-Nitrosalicylaldehyde Suppliers
- Tel
- 320-37350700
- Fax
- +32 (0)37350701
- sales@tcieurope.eu
- Country
- Europe
- ProdList
- 23671
- Advantage
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View Lastest Price from 3-Nitrosalicylaldehyde manufacturers
- Product
- 3-Nitrosalicylaldehyde 5274-70-4
- Price
- US $0.00-0.00/g
- Min. Order
- 10mg
- Purity
- 99%HPLC
- Supply Ability
- 2000tons
- Release date
- 2020-01-15
- Product
- 3-Nitrosalicylaldehyde 5274-70-4
- Price
- US $1.00/ASSAYS
- Min. Order
- 1ASSAYS
- Purity
- 98%
- Supply Ability
- 1kg,2kg,100kg
- Release date
- 2019-07-09