N-Isopropylbenzylamine
- Product Name
- N-Isopropylbenzylamine
- CAS No.
- 102-97-6
- Chemical Name
- N-Isopropylbenzylamine
- Synonyms
- Isopropylbenzylamine;Benzylisopropylamine;N-BENZYLISOPROPYLAMINE;N-benzylpropan-2-aMine;Benzylamine, N-isopropyl-;n-(1-methylethyl)-benzenemethanamine;AURORA KA-7714;N-Isopropylbenzylamine Crystal;n-(1-methylethyl)-benzenemethanamin;N-(1-Methylethyl)-benzeneMethanaMine hydrochloride
- CBNumber
- CB9199936
- Molecular Formula
- C10H15N
- Formula Weight
- 149.23
- MOL File
- 102-97-6.mol
N-Isopropylbenzylamine Property
- Melting point:
- 143°C (estimate)
- Boiling point:
- 200 °C(lit.)
- Density
- 0.892 g/mL at 25 °C(lit.)
- refractive index
- n20/D 1.502(lit.)
- Flash point:
- 190 °F
- storage temp.
- Store below +30°C.
- solubility
- Chloroform (Slightly), Ethy Acetate (Slightly), Methanol (Slightly)
- pka
- 9.77±0.19(Predicted)
- form
- Oil
- color
- Colourless
- BRN
- 2638437
- InChIKey
- LYBKPDDZTNUNNM-UHFFFAOYSA-N
- CAS DataBase Reference
- 102-97-6(CAS DataBase Reference)
- NIST Chemistry Reference
- Benzenemethanamine, N-(1-methylethyl)-(102-97-6)
- EPA Substance Registry System
- Benzenemethanamine, N-(1-methylethyl)- (102-97-6)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 8.41618
- Product name
- N-Isopropylbenzylamine
- Purity
- for synthesis
- Packaging
- 100mL
- Price
- $103
- Updated
- 2024/03/01
- Product number
- 136964
- Product name
- N-Isopropylbenzylamine
- Purity
- 97%
- Packaging
- 25g
- Price
- $59.1
- Updated
- 2024/03/01
- Product number
- B1216
- Product name
- N-Isopropylbenzylamine
- Purity
- >98.0%(GC)(T)
- Packaging
- 25mL
- Price
- $80
- Updated
- 2024/03/01
- Product number
- B1216
- Product name
- N-Isopropylbenzylamine
- Purity
- >98.0%(GC)(T)
- Packaging
- 500mL
- Price
- $400
- Updated
- 2024/03/01
- Product number
- B23243
- Product name
- N-Isopropylbenzylamine, 97%
- Packaging
- 100g
- Price
- $50.6
- Updated
- 2024/03/01
N-Isopropylbenzylamine Chemical Properties,Usage,Production
Chemical Properties
CLEAR VERY SLIGHTLY YELLOW TO YELLOW LIQUID
Uses
N-Isopropylbenzylamine, can be used as an intermediate in the synthesis of pharmaceutical compounds,and as a precursor to the manufacture of some drugs. Due to it’s similarity in appearance and physical properties to methamphetamine, it has been recently come under consideration of DEA.
Preparation
N-benzylisopropylamine is synthesized by the reduction reaction of N-isopropylbenzamide or prepared from benzylamine and acetone by reductive amination reaction.
Application
N-Isopropylbenzylamine was used as ligand in the preparation and characterization of bis(cyclopentadienyl)magnesium. It was also used in the synthesis of N-benzylideneisopropylamine-N-oxide.
General Description
N-isopropylbenzylamine is a structural isomer of methamphetamine, is one of the most common adulterants. It forms amine adducts with magnesocene at ambient temperature in toluene.
Cytotoxicity
The toxicity of N-isopropylbenzylamine was evaluated in SH-SY5Y, PC12, and SN4741 cell lines. Cells were treated with 0.3–10 mM N-isopropylbenzylamine for 24 hours, and cell viability was measured using MTT assay. N-isopropylbenzylamine concentration-dependently reduced cell viability in these cells. The IC50 values of N-isopropylbenzylamine on cell viability were 3.47, 1.49, and 3.21 mM for SH-SY5Y cells, PC12 cells, and SN4741 cells, respectively. N-isopropylbenzylamine produced toxicity in cell lines that model neurons. Moreover, the activation of nNOS and the production of intracellular NO might be involved in N-isopropylbenzylamine-induced toxicity in SN4741 cells[1].
References
[1] Peng Xu . “N-isopropylbenzylamine, a methamphetamine mimics, produces toxicity via increasing nitric oxide in vitro.” Toxicology 480 (2022): Article 153337.
N-Isopropylbenzylamine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from N-Isopropylbenzylamine manufacturers
- Product
- Benzylisopropylamine 102-97-6
- Price
- US $2000.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 2000kg
- Release date
- 2024-05-15
- Product
- N-Isopropylbenzylamine 102-97-6
- Price
- US $10.00/ASSAYS
- Min. Order
- 1ASSAYS
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2024-03-26
- Product
- Benzylisopropylamine 102-97-6
- Price
- US $6.00/kg
- Min. Order
- 1kg
- Purity
- More than 99%
- Supply Ability
- 2000KG/Month
- Release date
- 2024-06-07