ChemicalBook > CAS DataBase List > 5-AMINO-1-(4-CHLOROPHENYL)-1H-PYRAZOLE-4-CARBONITRILE

5-AMINO-1-(4-CHLOROPHENYL)-1H-PYRAZOLE-4-CARBONITRILE

Product Name: 5-AMINO-1-(4-CHLOROPHENYL)-1H-PYRAZOLE-4-CARBONITRILE
CAS No.: 51516-67-7
Chemical Name: 5-AMINO-1-(4-CHLOROPHENYL)-1H-PYRAZOLE-4-CARBONITRILE
Synonyms: BUTTPARK 87\09-40;5-Amino-1-(4-chlorophenyl);5-AMINO-1-(4-CHLOROPHENYL)-1H-PYRAZOLE-&;5-aMino-1-(4-chlorophenyl)-1H-pyrazole-4-;5-AMINO-4-CYANO-1-(4-CHLOROPHENYL)PYRAZOLE;5-AMINO-1-(4-CHLOROPHENYL)-4-CYANOPYRAZOLE;5-amino-1 -(4-chlorophenyl) -4-cyano-1H-pyrazole;5-Amino-1-(4-chlorophenyl)pyrazole-4-carbonitrile;5-AMINO-1-(4-CHLOROPHENYL)-1H-PYRAZOLE-4-CARBONITRILE;1H-Pyrazole-4-carbonitrile, 5-amino-1-(4-chlorophenyl)-
CBNumber: CB9203976
Molecular Formula: C10H7ClN4
Formula Weight: 218.64
MOL File: 51516-67-7.mol

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5-AMINO-1-(4-CHLOROPHENYL)-1H-PYRAZOLE-4-CARBONITRILE Property

Melting point:: 169-173 °C
Boiling point:: 424.2±40.0 °C(Predicted)
Density: 1.41±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
pka: -1.15±0.10(Predicted)
form: solid
Appearance: Light brown to yellow Solid

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Safety

Hazard Codes: Xn
Risk Statements: 22-37/38-41-36/37/38-20/21/22
Safety Statements: 26-36/39-36/37/39-22
RIDADR: UN3439
WGK Germany: 3
HazardClass: 6.1
PackingGroup: III
HS Code: 29331990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 659398
Product name: 5-Amino-1-(4-chlorophenyl)-1H-pyrazole-4-carbonitrile
Purity: 97%
Packaging: 1g
Price: $62
Updated: 2023/06/20

Sigma-Aldrich

Product number: 659398
Product name: 5-Amino-1-(4-chlorophenyl)-1H-pyrazole-4-carbonitrile
Purity: 97%
Packaging: 5g
Price: $204
Updated: 2023/06/20

American Custom Chemicals Corporation

Product number: COR0003269
Product name: 5-AMINO-1-(4-CHLOROPHENYL)-1H-PYRAZOLE-4-CARBONITRILE
Purity: 95.00%
Packaging: 5G
Price: $1661.47
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: COR0003269
Product name: 5-AMINO-1-(4-CHLOROPHENYL)-1H-PYRAZOLE-4-CARBONITRILE
Purity: 95.00%
Packaging: 10G
Price: $2255.72
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: COR0003269
Product name: 5-AMINO-1-(4-CHLOROPHENYL)-1H-PYRAZOLE-4-CARBONITRILE
Purity: 95.00%
Packaging: 25G
Price: $3565.49
Updated: 2021/12/16

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5-AMINO-1-(4-CHLOROPHENYL)-1H-PYRAZOLE-4-CARBONITRILE Chemical Properties,Usage,Production

Chemical Properties

White to off-white crystalline powder

Synthesis

1073-69-4

123-06-8

51516-67-7

GENERAL METHOD: 4-Chlorophenylhydrazine (0.001 mol) was mixed with 10 mL of ethanol, stirred and heated to reflux. Subsequently, ethoxymethylene malononitrile (0.001 mol) dissolved in 10 mL of ethanol was added slowly and dropwise. The reaction mixture was kept at reflux for 2 hours. After completion of the reaction, the mixture was poured into 50 mL of ice water. The precipitate precipitated was collected by filtration and washed with cold water to afford 5-amino-1-(4-chlorophenyl)-1H-pyrazole-4-carbonitrile in 61-80% yield.

References

[1] Heterocyclic Communications, 2005, vol. 11, # 5, p. 385 - 388
[2] Medicinal Chemistry Research, 2018, vol. 27, # 8, p. 1876 - 1884
[3] European Journal of Medicinal Chemistry, 2008, vol. 43, # 4, p. 771 - 780
[4] Journal of Medicinal Chemistry, 1991, vol. 34, # 9, p. 2892 - 2898
[5] Australian Journal of Chemistry, 1989, vol. 42, # 5, p. 747 - 750

5-AMINO-1-(4-CHLOROPHENYL)-1H-PYRAZOLE-4-CARBONITRILE Preparation Products And Raw materials

Raw materials

Malononitrile Triethyl orthoformate Stannous chloride Sodium nitrite Hydrochloric acid 4-Chloroaniline

Preparation Products

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5-AMINO-1-(4-CHLOROPHENYL)-1H-PYRAZOLE-4-CARBONITRILE Suppliers

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51516-67-7, 5-AMINO-1-(4-CHLOROPHENYL)-1H-PYRAZOLE-4-CARBONITRILERelated Search:

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5-AMINO-1-(4-CHLOROPHENYL)-1H-PYRAZOLE-&

5-Amino-1-(4-chlorophenyl)pyrazole-4-carbonitrile

5-AMINO-1-(4-CHLOROPHENYL)-4-CYANOPYRAZOLE

5-AMINO-4-CYANO-1-(4-CHLOROPHENYL)PYRAZOLE

5-AMINO-1-(4-CHLOROPHENYL)-1H-PYRAZOLE-4-CARBONITRILE

BUTTPARK 87\09-40

5-Amino-1-(4-chlorophenyl)-1H-pyrazole-4-carbonitrile ,97%

5-Amino-1-(4-chlorophenyl)

5-aMino-1-(4-chlorophenyl)-1H-pyrazole-4-

1H-Pyrazole-4-carbonitrile, 5-amino-1-(4-chlorophenyl)-

5-amino-1 -(4-chlorophenyl) -4-cyano-1H-pyrazole

5-Amino-1-(4-chlorophenyl)-1<i>H</i>-pyrazole-4-carbonitrile

51516-67-7

Heterocyclic Building Blocks

Halogenated Heterocycles

Pyrazoles

Building Blocks

Halogenated Heterocycles

Heterocyclic Building Blocks

Pyrazoles

PyrazolesHeterocyclic Building Blocks