ALPHA-METHYLBENZYL ALCOHOL Property

Melting point:

19-20 °C(lit.)

Boiling point:

204 °C745 mm Hg(lit.)

Density 

1.012 g/mL at 25 °C(lit.)

vapor density 

4.21 (vs air)

vapor pressure 

0.1 mm Hg ( 20 °C)

refractive index 

n20/D 1.527(lit.)

Flash point:

185 °F

Dielectric constant

7.6（90℃）

CAS DataBase Reference

13323-81-4(CAS DataBase Reference)

Safety

Hazard Codes 

Xn

Risk Statements 

22-38-41

Safety Statements 

26-39

RIDADR 

UN 2937 6.1/PG 3

WGK Germany 

1

RTECS 

DO9275000

HazardClass 

6.1

PackingGroup 

III

Toxicity

The acute oral LD₅₀ in rats was reported as 400 mg/kg (Smyth & Carpenter, 1944). The acute dermal LD₅₀ value in rabbits exceeded 2.5 g/kg (Moreno, 1973).

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

ALPHA-METHYLBENZYL ALCOHOL Chemical Properties,Usage,Production

Chemical Properties

Colorless liquid

Occurrence

Has apparently not been reported to occur in nature.

Preparation

By hydrogenation or reduction of acetophenone; or from methyl magnesium chloride plus benzaldehyde by a Grignard-type reaction (Bedoukian, 1967).

Definition

ChEBI: 1-phenylethanol is an aromatic alcohol that is ethanol substituted by a phenyl group at position 1. It has a role as a mouse metabolite.

Metabolism

Styrallyl alcohol is converted in rabbits into hippuric acid and methylphenylcarbinyl glucuronide, both optical forms of the carbinol behaving similarly. A small proportion (1-2%) is excreted as mandelic acid (Wjlliams, 1959).

Purification Methods

Purify the alcohol via its hydrogen phthalate. [See Houssa & Kenyon J Chem Soc 2260 1930.] Shake it with a solution of ferrous sulfate, and th