Preparation method Chemical Characteristics Uses
ChemicalBook > CAS DataBase List > 4-Trifluoromethylphenol

4-Trifluoromethylphenol

Preparation method Chemical Characteristics Uses
Product Name
4-Trifluoromethylphenol
CAS No.
402-45-9
Chemical Name
4-Trifluoromethylphenol
Synonyms
TFMPO;TRIFLUORO-PARA-CRESOL;Fluoxetine Impurity 4;4-HYDROXYBENZOTRIFLUORI;4-trifluorotoluolphenol;p-TrifluoroMethylphenyl;α,α,α-Trifluoro-p-cresol;4-HYDROXYBENZOTRIFLUORIDE;4-(TRIFLUOROMETHYL)PHENOL;P-(TRIFLUOROMETHYL)PHENOL
CBNumber
CB6371577
Molecular Formula
C7H5F3O
Formula Weight
162.11
MOL File
402-45-9.mol
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4-Trifluoromethylphenol Property

Melting point:
45-47 °C(lit.)
Boiling point:
71.5-72 °C (8 mmHg)
Density 
1.3226 (estimate)
Flash point:
183 °F
storage temp. 
0-6°C
form 
Crystals
pka
pK1:8.675 (25°C)
color 
White to yellow-brown
BRN 
1637019
CAS DataBase Reference
402-45-9(CAS DataBase Reference)
NIST Chemistry Reference
p-Hydroxybenzotrifluoride(402-45-9)
EPA Substance Registry System
Phenol, 4-(trifluoromethyl)-(402-45-9)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-37/38-41-36/37/38
Safety Statements 
26-39-24/25
RIDADR 
UN 2926 4.1/PG 2
WGK Germany 
3
Hazard Note 
Irritant/Keep Cold
PackingGroup 
HS Code 
29081000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H228Flammable solid

H301Toxic if swalloed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
178470
Product name
4-(Trifluoromethyl)phenol
Purity
97%
Packaging
1g
Price
$26.1
Updated
2018/11/13
Sigma-Aldrich
Product number
178470
Product name
4-(Trifluoromethyl)phenol
Purity
97%
Packaging
5g
Price
$81.2
Updated
2018/11/13
TCI Chemical
Product number
H0644
Product name
4-Hydroxybenzotrifluoride
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$93
Updated
2018/11/22
TCI Chemical
Product number
H0644
Product name
4-Hydroxybenzotrifluoride
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$278
Updated
2018/11/22
Sigma-Aldrich
Product number
178470
Product name
4-(Trifluoromethyl)phenol
Purity
97%
Packaging
25g
Price
$293
Updated
2018/11/13
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4-Trifluoromethylphenol Chemical Properties,Usage,Production

Preparation method

Chlorosilane and bromotrifluoromethane at-59℃form trifluoromethylsilane. Trifluoromethylsilane and benzoquinone in the presence of catalyst form 4-triethylsiloxy-4-trifluoromethyl-2,5-cyclohexadien-1-ketone which is reduced by zinc powder to p-trifluoromethylphenol with a yield of 71%. This method avoids the use of  hydrofluoric acid in the traditional process but  should be carried out under anhydrous conditions.If there were water trifluoromethyl silane would rapidly become silanol under the effect of water and alkali. The catalyst used in the reaction is alkali of which the strength has nothing to do with the catalytic activity. By now the role of catalyst is still unknown but the reaction can not proceed without catalyst.

Chemical Characteristics

Off-white crystal

Uses

For intermediate of medicine and pesticide.

Chemical Properties

White to yellowish-brown crystals

Uses

Intermediates of Liquid Crystals

4-Trifluoromethylphenol Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Trifluoromethylphenol Suppliers

Beijing Xinsavi Chemical Technology Co., Ltd.
Tel
13717722232
Fax
010-56218800
Email
xinsavichem@163.com
Country
China
ProdList
4822
Advantage
56
Cool Pharm, Ltd
Tel
+86 (21) 6045-5363;+86 (21)58581007;18019463053//QQ:3111763154
Fax
+86 (21) 5096-6098
Email
alan@coolpharm.com
Country
China
ProdList
9848
Advantage
58
J & K SCIENTIFIC LTD.
Tel
400-666-7788 +86-10-82848833
Fax
86-10-82849933
Email
jkinfo@jkchemical.com;market6@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Changzhou Sunchem Pharmaceutical Chemical Material Co., Ltd
Tel
+86-519-85195575; 85195565; 15861192208
Fax
+86-519-85195585
Email
info@sunkechem.com
Country
China
ProdList
98
Advantage
69
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
+86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)
Fax
+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing)
Email
sh@meryer.com
Country
China
ProdList
40269
Advantage
62
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386 / 800-988-0390
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24555
Advantage
81
Beijing dtftchem Technology Co., Ltd.
Tel
13651141086; 86(10)60275028、60275820
Fax
86 (10) 60270825
Email
dtftchem@sina.com
Country
China
ProdList
3393
Advantage
62
BeiJing Hwrk Chemicals Limted
Tel
4006990298;010-57411839;0757-86311057;021-51691807
Fax
010-87653215;0757-86311057;021-55236763
Email
sales@hwrkchemical.com
Country
China
ProdList
14684
Advantage
55
Energy Chemical
Tel
021-58432009 / 400-005-6266
Fax
021-58436166-800
Email
info@energy-chemical.com
Country
China
ProdList
44025
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18228
Advantage
66
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View Lastest Price from 4-Trifluoromethylphenol manufacturers

career henan chemical co
Product
4-Trifluoromethylphenol 402-45-9
Price
US $100.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
Customized
Release date
2018-08-02

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