4-Trifluoromethylphenol

Preparation method Chemical Characteristics Uses

Product Name: 4-Trifluoromethylphenol
CAS No.: 402-45-9
Chemical Name: 4-Trifluoromethylphenol
Synonyms: TFMPO;TRIFLUORO-PARA-CRESOL;Fluoxetine Impurity 4;4-HYDROXYBENZOTRIFLUORI;4-trifluorotoluolphenol;p-TrifluoroMethylphenyl;α,α,α-Trifluoro-p-cresol;4-HYDROXYBENZOTRIFLUORIDE;4-(TRIFLUOROMETHYL)PHENOL;P-(TRIFLUOROMETHYL)PHENOL
CBNumber: CB6371577
Molecular Formula: C7H5F3O
Formula Weight: 162.11
MOL File: 402-45-9.mol

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4-Trifluoromethylphenol Property

Melting point:: 45-47 °C(lit.)
Boiling point:: 71.5-72 °C (8 mmHg)
Density: 1.3226 (estimate)
Flash point:: 183 °F
storage temp.: 0-6°C
form: Crystals
pka: pK1:8.675 (25°C)
color: White to yellow-brown
BRN: 1637019
CAS DataBase Reference: 402-45-9(CAS DataBase Reference)
NIST Chemistry Reference: p-Hydroxybenzotrifluoride(402-45-9)
EPA Substance Registry System: Phenol, 4-(trifluoromethyl)-(402-45-9)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 22-37/38-41-36/37/38
Safety Statements: 26-39-24/25
RIDADR: UN 2926 4.1/PG 2
WGK Germany: 3
Hazard Note: Irritant/Keep Cold
PackingGroup: Ⅱ
HS Code: 29081000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H228Flammable solid

H301Toxic if swalloed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 178470
Product name: 4-(Trifluoromethyl)phenol
Purity: 97%
Packaging: 1g
Price: $26.1
Updated: 2018/11/13

Sigma-Aldrich

Product number: 178470
Product name: 4-(Trifluoromethyl)phenol
Purity: 97%
Packaging: 5g
Price: $81.2
Updated: 2018/11/13

TCI Chemical

Product number: H0644
Product name: 4-Hydroxybenzotrifluoride
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $93
Updated: 2018/11/22

TCI Chemical

Product number: H0644
Product name: 4-Hydroxybenzotrifluoride
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $278
Updated: 2018/11/22

Sigma-Aldrich

Product number: 178470
Product name: 4-(Trifluoromethyl)phenol
Purity: 97%
Packaging: 25g
Price: $293
Updated: 2018/11/13

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4-Trifluoromethylphenol Chemical Properties,Usage,Production

Preparation method

Chlorosilane and bromotrifluoromethane at-59℃form trifluoromethylsilane. Trifluoromethylsilane and benzoquinone in the presence of catalyst form 4-triethylsiloxy-4-trifluoromethyl-2,5-cyclohexadien-1-ketone which is reduced by zinc powder to p-trifluoromethylphenol with a yield of 71%. This method avoids the use of hydrofluoric acid in the traditional process but should be carried out under anhydrous conditions.If there were water trifluoromethyl silane would rapidly become silanol under the effect of water and alkali. The catalyst used in the reaction is alkali of which the strength has nothing to do with the catalytic activity. By now the role of catalyst is still unknown but the reaction can not proceed without catalyst.

Chemical Characteristics

Off-white crystal

Uses

For intermediate of medicine and pesticide.

Chemical Properties

White to yellowish-brown crystals

Uses

Intermediates of Liquid Crystals

4-Trifluoromethylphenol Preparation Products And Raw materials

Raw materials

Preparation Products

4-(TRIFLUOROMETHYL)PHENOXYACETIC ACID

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4-Trifluoromethylphenol Suppliers

Belgium 1 China 235 Europe 3 France 1 Germany 4 India 2 Japan 4 Slovakia 1 Switzerland 1 Ukraine 2 United Kingdom 11 United States 42 Global 307

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Energy Chemical

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View Lastest Price from 4-Trifluoromethylphenol manufacturers

career henan chemical co

Product: 4-Trifluoromethylphenol 402-45-9
Price: US $100.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: Customized
Release date: 2018-08-02

402-45-9, 4-TrifluoromethylphenolRelated Search:

2-(4-METHYLPHENOXY)-5-(TRIFLUOROMETHYL)ANILINE 4-(4-METHOXYPHENOXY)-3-NITROBENZOTRIFLUORIDE 4-(4-CHLORO-3-METHYLPHENOXY)-3-NITROBENZOTRIFLUORIDE 2-AMINO-4'-CHLORO-4-TRIFLUOROMETHYL DIPHENYL ETHER 4-METHOXY-3-NITROBENZOTRIFLUORIDE 4-Hydroxy-3-nitrobenzotrifluoride 4-Trifluoromethylphenol 4-Trifluoromethylphenylboronic acid p-Cresol alpha,alpha,alpha-Trifluoro-o-toluoyl chloride 2-(Trifluoromethyl)benzoic acid Diethylstilbestrol Xylenol o-Cresol 4-(Trifluoromethyl)cinnamic acid 4-(Trifluoromethyl)benzene-1-sulfonyl chloride Trifluoromethanesulfonic acid Cresol

alpha,alpha,alpha-Trifluoro-p-cresol,loosecrystals

Phenol, 4-(trifluoromethyl)-

P-HYDROXYBENZOTRIFLUORIDE

P-(TRIFLUOROMETHYL)PHENOL

ALPHA,ALPHA,ALPHA-TRIFLUORO-4-CRESOL

ALPHA,ALPHA,ALPHA-TRIFLUORO-P-CRESOL

4-(TRIFLUOROMETHYL)PHENOL

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4-HYDROXY-ALPHA,ALPHA,ALPHA-TRIFLUOROTOLUENE

4-Hydroxy-α,α,α-trifluorotoluene

α,α,α-Trifluoro-p-cresol

4-Hydroxybenxotrifluoride

ALPHA,ALPHA,ALPHA-TRIFLUORO-P-CRESOL, 99 %

alpha,alpha,alpha-Trifluoro-p-cresol&#65307

4-HydroxytrifluoromethylBenzene

4-Hydroxybenzotrifluoride,98%

4-Hydroxybenzotrifluoride99%

4-Hydroxybenzotrifluoride 99%

TRIFLUORO-PARA-CRESOL

4/p-Trifluoromethylaniline

α,α,α-Trifluoro-p-cresol, 4-Hydroxybenzotrifluoride

TFMPO

alpha,alpha,alpha-Trifluoro-p-cresol,98%

4-HYDROXYBENZOTRIFLUORI

4-(Trifluoromethyl)phenol ,98%

4-trifluorotoluolphenol

alpha,alpha,alpha-Trifluoro-p-cresol, 98% 1GR

alpha,alpha,alpha-Trifluoro-p-cresol, 98% 5GR

4-Hydroxy-alpha,alpha,alpha-trifluorotoluene alpha,alpha,alpha-Trifluoro-p-cresol 4-(Trifluoromethyl)phenol

p-TrifluoroMethylphenyl

4-(TrifluoroMethyl)phenol 97%

4-(TrifluoroMethyl)phenol, 97+%

α,α,α-Trifluoro-p-cresol 4-Hydroxybenzotrifluoride 4-Hydroxy-α,α,α-trifluorotoluene p-Hydroxybenzotrifluoride p-Trifluoromethylphenol

4-Hydroxybenzotrifluoride for synthesis

Fluoxetine Impurity 4

Fluoxetine Impurity 4(EP-D)

402-45-9

402-56-9

C7H5F3O

Oxygen Compounds

Phenols

Organic Building Blocks

Building Blocks

Trifluoromethylbenzene serise

Aromatic Phenols

Phenol&Thiophenol&Mercaptan

Fluorochemicals