ChemicalBook > CAS DataBase List > N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine

N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine

Product Name
N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine
CAS No.
309-88-6
Chemical Name
N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine
Synonyms
Ishikawa;Ishikawa Reagent;N,N-Diethyl-1,1,2,3,3,3-hexafluoropropan-1-amine;MEC-81;Ishikawas;UNII:N4Y8BIM7UD;SHIKAWA'S REAGENT;ISHIKAWA'S REAGENT;Ishikawa’s Reagent;Ishikawa's Reagent 
CBNumber
CB9205718
Molecular Formula
C7H11F6N
Formula Weight
223.16
MOL File
309-88-6.mol
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N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine Property

Boiling point:
56-57 °C (lit.)
Density 
1.230 g/mL at 25 °C (lit.)
refractive index 
1.3460
Flash point:
56-57°C/58mm
storage temp. 
Flammables area
solubility 
soluble in Acetone,Ether
pka
1.50±0.70(Predicted)
form 
Liquid
color 
Clear colorless to yellow
Specific Gravity
1.230
Merck 
14,5108
CAS DataBase Reference
309-88-6(CAS DataBase Reference)
EPA Substance Registry System
N,N-Diethyl-2H-perfluoropropanamine (309-88-6)
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Safety

Hazard Codes 
C
Risk Statements 
10-34
Safety Statements 
16-26-36/37/39-45
RIDADR 
3267
WGK Germany 
3
Hazard Note 
Corrosive
HazardClass 
8
PackingGroup 
II
HS Code 
29211999
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H226Flammable liquid and vapour

H314Causes severe skin burns and eye damage

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
564990
Product name
N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine
Packaging
25g
Price
$170
Updated
2024/03/01
TCI Chemical
Product number
H0598
Product name
Ishikawa's Reagent [Fluorinating Reagent]
Purity
>92.0%(T)
Packaging
25g
Price
$78
Updated
2024/03/01
TCI Chemical
Product number
H0598
Product name
Ishikawa's Reagent [Fluorinating Reagent]
Purity
>92.0%(T)
Packaging
100g
Price
$229
Updated
2024/03/01
Alfa Aesar
Product number
L16738
Product name
Ishikawa's Reagent, 90+%
Packaging
25g
Price
$79.65
Updated
2024/03/01
Alfa Aesar
Product number
L16738
Product name
Ishikawa's Reagent, 90+%
Packaging
100g
Price
$263.65
Updated
2024/03/01
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N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine Chemical Properties,Usage,Production

Chemical Properties

Clear colorless to yellow liquid

Uses

Demonstrates utility in fluorination.7

Uses

Reactant for:

  • Friedel-Crafts type arylation of hydrofluorocarbons
  • Microbial hydroxylation of antibiotics
  • Electrochemical fluorination of trialkylamines and tetraalkylammonium salts
  • Fluorination of pyrethroides

Reactant for synthesis of:
  • γ-Hydroxy-α-fluoro-α-trifluoromethylcarboxamide
  • Florfenicol and thiamphenicol

Uses

Fluorinating agent.

General Description

GC analysis includes Et2NCF=CFCF3 (two isomers), both of which are active fluorinating agents.

N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine Preparation Products And Raw materials

Raw materials

Preparation Products

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N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine Suppliers

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Pure Chemistry Scientific Inc.
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View Lastest Price from N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine manufacturers

Career Henan Chemical Co
Product
N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine 309-88-6
Price
US $1.00/KG
Min. Order
1KG
Purity
98-100%
Supply Ability
1000kg
Release date
2018-08-20

309-88-6, N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamineRelated Search:

2-Aminoethyl(ethyl)amine N,N-Diethylaniline N-Ethylcarbazole Diethyl malonate Hexafluoroethane Isopropylamine Diethyl phthalate Diisopropylammonium dichloroacetate (-)-2-[METHYLAMINO]-1-PHENYLPROPANE Perfluorotripropylamine Diethyl ether Celiprolol D/L-AMPHETAMINE HYDROCHLORIDE TRIETHYLAMINE PENTAHYDROFLUORIDE 3,3,3-TRIFLUOROPROPYLAMINE DIFLUOROMETHYLDIMETHYLAMINE N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine SALOR-INT L173401-1EA

  • SHIKAWA'S REAGENT
  • N,N-DIETHYL-1,1,2,3,3,3-HEXAFLUOROPROPYLAMINE
  • Ishikawa's Reagent, 1-(Diethylamino)-1,1,2,3,3,3-hexafluoropropane
  • N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine, 40% solution in THF
  • Ishikawa
  • Ishikawa's Reagent, technical, 90%
  • Ishikawa Reagent
  • MEC-81
  • 1,1,2,3,3,3-HEXAFLUORO-1-DIETHYLAMINO-PROPAN
  • 1,1,2,3,3,3-HEXAFLUORO-1-DIETHYLAMINOPROPANE
  • N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine 97%
  • N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine97%
  • ISHIKAWA''S REAGENT: TECH., 90%
  • DIETHYL-(1,1,2,3,3,3-HEXAFLUOROPROPYL)AMINE
  • Ishikawa's Reagent [Fluorinating Reagent]
  • Ishikawas
  • N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine, 40-50% in diglyme
  • Hexafluoro-1-diethylamino-propane
  • ISHIKAWA'S REAGENT
  • N,N-Diethyl-1,1,2,3,3,3-hexafluoropropan-1-amine
  • 1,1,2,3,3,3-Hexafluoropropyldiethylamine
  • N,N-Diethyl-1,1,2,3,3,3-hexafluoropropane-1-amine
  • N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine,90%
  • Ishikawa's Reagent, 90+%
  • Hexafluoropropene Diethylamine N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine
  • Ishikawa's Reagent&nbsp
  • N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine(Ishikawa's reagent)
  • N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine in acetonitrile
  • N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine in butyl diglyme
  • N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine in dibutyl ether
  • N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine in diglyme
  • Ishikawa'sReagent[FluorinatingReagent]&gt
  • 1-Propanamine, N,N-diethyl-1,1,2,3,3,3-hexafluoro-
  • Ishikawa’s Reagent
  • UNII:N4Y8BIM7UD
  • N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine (Ishikawa's reagent)
  • 309-88-6
  • CF3CHFCF2NC2H52
  • C7H11F6N
  • C-X Bond Formation (Halogen)
  • Synthetic Reagents
  • Fluorination
  • Fluorinated Building Blocks
  • Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds
  • Fluorination
  • Halogenation
  • Synthetic Organic Chemistry
  • Chemical Synthesis
  • Fluorination Reagents
  • Synthetic Reagents