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2-Nitroacetophenone

Product Name
2-Nitroacetophenone
CAS No.
577-59-3
Chemical Name
2-Nitroacetophenone
Synonyms
1-(2-nitrophenyl)ethanone;NSC 3641;AKOS 233-65;AURORA 14018;AKOS BBS-00003220;2-Nitroacetophene;2'-Nitroacetophne;2-NITROACETOPHENONE;O-NITROACETOPHENONE;2’-nitro-acetophenon
CBNumber
CB9208092
Molecular Formula
C8H7NO3
Formula Weight
165.15
MOL File
577-59-3.mol
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2-Nitroacetophenone Property

Melting point:
76-78 °C(lit.)
Boiling point:
202 °C(lit.)
Density 
1.23
refractive index 
n20/D 1.55(lit.)
Flash point:
>230 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform, Ethyl Acetate
form 
Solid
color 
Brown
Water Solubility 
Insoluble
FreezingPoint 
24.0 to 28.0 ℃
BRN 
1102322
Stability:
Stable. Combustible. Incompatible with strong oxidizing agents.
CAS DataBase Reference
577-59-3(CAS DataBase Reference)
NIST Chemistry Reference
Ethanone, 1-(2-nitrophenyl)-(577-59-3)
EPA Substance Registry System
2-Nitroacetophenone (577-59-3)
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Safety

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
AM9625000
Hazard Note 
Harmful
TSCA 
Yes
HS Code 
29147090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
N9209
Product name
2′-Nitroacetophenone
Purity
95%
Packaging
10g
Price
$28.3
Updated
2024/03/01
Sigma-Aldrich
Product number
N9209
Product name
2′-Nitroacetophenone
Purity
95%
Packaging
1g
Price
$22.8
Updated
2022/05/15
TCI Chemical
Product number
N0110
Product name
2'-Nitroacetophenone
Purity
>96.0%(GC)
Packaging
5g
Price
$20
Updated
2024/03/01
TCI Chemical
Product number
N0110
Product name
2'-Nitroacetophenone
Purity
>96.0%(GC)
Packaging
25g
Price
$55
Updated
2024/03/01
Alfa Aesar
Product number
A13208
Product name
2'-Nitroacetophenone, 97%
Packaging
10g
Price
$79.65
Updated
2024/03/01
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2-Nitroacetophenone Chemical Properties,Usage,Production

Chemical Properties

yellow-green liquid or crystals. Soluble in alcohol, ether and chloroform, slightly soluble in water.

Uses

2'-Nitroacetophenone is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and dyestuff. It is also used as a synthetic reagent. It is the sensitizer which can be used as pharmaceutical intermediates.

Uses

2''-Nitroacetophenone (cas# 577-59-3) is a compound useful in organic synthesis. It is also used as an intermediate for photosensitive materials.?

Preparation

o-Nitroacetophenone is synthesized from o-nitroethylbenzene by oxidation. Add o-nitroethylbenzene, decanoic acid and initiator azobisisobutyronitrile into the reaction tower, and at the same time slowly pass air into the tower, keep the pressure at 0.3-0.8MPa, and control the oxidation at 120-130°C to generate 2-Nitroacetophenone.

Synthesis Reference(s)

The Journal of Organic Chemistry, 43, p. 3631, 1978 DOI: 10.1021/jo00412a058
Journal of the American Chemical Society, 105, p. 943, 1983 DOI: 10.1021/ja00342a050
Synthesis, p. 228, 1988 DOI: 10.1055/s-1988-27522

General Description

Clear yellow liquid. Insoluble in water.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

A nitrated ketone. Ketones are reactive with many acids and bases liberating heat and flammable gases (e.g., H2). The amount of heat may be sufficient to start a fire in the unreacted portion of the ketone. Ketones react with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas (H2) and heat. Ketones are incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides. They react violently with aldehydes, HNO3, HNO3 + H2O2, and HClO4.

Fire Hazard

2-Nitroacetophenone is combustible.

2-Nitroacetophenone Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Nitroacetophenone Suppliers

Zhangjiagang Free Trade Zone Kailite Chemical Co., Ltd.
Tel
18606289633 15862625988
Fax
0512-58813106
Email
sales@clentchem.com
Country
China
ProdList
196
Advantage
60
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
Advantage
56
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Beijing dtftchem Technology Co., Ltd.
Tel
010-60275820 13031183356
Fax
010-60270825
Email
elainezt@sina.com
Country
China
ProdList
1390
Advantage
62
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12438
Advantage
60
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View Lastest Price from 2-Nitroacetophenone manufacturers

Hebei Chuanghai Biotechnology Co,.LTD
Product
2-Nitroacetophenone 577-59-3
Price
US $20.60/KG
Min. Order
1KG
Purity
99%
Supply Ability
5000kg
Release date
2024-08-09
Shaanxi Dideu Medichem Co. Ltd
Product
2-Nitroacetophenone 577-59-3
Price
US $555.00/ASSAYS
Min. Order
1ASSAYS
Purity
98%
Supply Ability
1T
Release date
2020-06-28
Hebei Weibang Biotechnology Co., Ltd
Product
2-Nitroacetophenone 577-59-3
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2021-10-25

577-59-3, 2-NitroacetophenoneRelated Search:


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  • AKOS 233-65
  • 2'-Nitroacetophenone&gt
  • 2'-Nitroacetophne
  • 2'-Nitroacetophenone
  • 577-59-3
  • CH3COC6H4NO2
  • NO2C6H4COCH3
  • C8H7BNO3
  • KETONE
  • Building Blocks
  • C7 to C8
  • Carbonyl Compounds
  • Ketones
  • Organic Building Blocks
  • Aromatic Acetophenones & Derivatives (substituted)
  • Aromatics
  • Miscellaneous Reagents
  • C7 to C8
  • Carbonyl Compounds
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  • pharmaceutical intermediates
  • Carbonyl Compounds