ChemicalBook > CAS DataBase List > 2-Nitroacetophenone

2-Nitroacetophenone

Product Name
2-Nitroacetophenone
CAS No.
577-59-3
Chemical Name
2-Nitroacetophenone
Synonyms
1-(2-nitrophenyl)ethanone;NSC 3641;AKOS 233-65;AURORA 14018;AKOS BBS-00003220;2-Nitroacetophene;2'-Nitroacetophne;2-NITROACETOPHENONE;O-NITROACETOPHENONE;2’-nitro-acetophenon
CBNumber
CB9208092
Molecular Formula
C8H7NO3
Formula Weight
165.15
MOL File
577-59-3.mol
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2-Nitroacetophenone Property

Melting point:
76-78 °C(lit.)
Boiling point:
202 °C(lit.)
Density 
1.23
refractive index 
n20/D 1.55(lit.)
Flash point:
>230 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform, Ethyl Acetate
form 
Solid
color 
Brown
Water Solubility 
Insoluble
FreezingPoint 
24.0 to 28.0 ℃
BRN 
1102322
Stability:
Stable. Combustible. Incompatible with strong oxidizing agents.
CAS DataBase Reference
577-59-3(CAS DataBase Reference)
NIST Chemistry Reference
Ethanone, 1-(2-nitrophenyl)-(577-59-3)
EPA Substance Registry System
2-Nitroacetophenone (577-59-3)
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Safety

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
AM9625000
Hazard Note 
Harmful
TSCA 
Yes
HS Code 
29147090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
N9209
Product name
2′-Nitroacetophenone
Purity
95%
Packaging
10g
Price
$28.3
Updated
2024/03/01
Sigma-Aldrich
Product number
N9209
Product name
2′-Nitroacetophenone
Purity
95%
Packaging
1g
Price
$22.8
Updated
2022/05/15
TCI Chemical
Product number
N0110
Product name
2'-Nitroacetophenone
Purity
>96.0%(GC)
Packaging
5g
Price
$20
Updated
2024/03/01
TCI Chemical
Product number
N0110
Product name
2'-Nitroacetophenone
Purity
>96.0%(GC)
Packaging
25g
Price
$55
Updated
2024/03/01
Alfa Aesar
Product number
A13208
Product name
2'-Nitroacetophenone, 97%
Packaging
10g
Price
$79.65
Updated
2024/03/01
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2-Nitroacetophenone Chemical Properties,Usage,Production

Chemical Properties

yellow-green liquid or crystals. Soluble in alcohol, ether and chloroform, slightly soluble in water.

Uses

2'-Nitroacetophenone is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and dyestuff. It is also used as a synthetic reagent. It is the sensitizer which can be used as pharmaceutical intermediates.

Uses

2''-Nitroacetophenone (cas# 577-59-3) is a compound useful in organic synthesis. It is also used as an intermediate for photosensitive materials.?

Preparation

o-Nitroacetophenone is synthesized from o-nitroethylbenzene by oxidation. Add o-nitroethylbenzene, decanoic acid and initiator azobisisobutyronitrile into the reaction tower, and at the same time slowly pass air into the tower, keep the pressure at 0.3-0.8MPa, and control the oxidation at 120-130°C to generate 2-Nitroacetophenone.

Synthesis Reference(s)

The Journal of Organic Chemistry, 43, p. 3631, 1978 DOI: 10.1021/jo00412a058
Journal of the American Chemical Society, 105, p. 943, 1983 DOI: 10.1021/ja00342a050
Synthesis, p. 228, 1988 DOI: 10.1055/s-1988-27522

General Description

Clear yellow liquid. Insoluble in water.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

A nitrated ketone. Ketones are reactive with many acids and bases liberating heat and flammable gases (e.g., H2). The amount of heat may be sufficient to start a fire in the unreacted portion of the ketone. Ketones react with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas (H2) and heat. Ketones are incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides. They react violently with aldehydes, HNO3, HNO3 + H2O2, and HClO4.

Fire Hazard

2-Nitroacetophenone is combustible.

2-Nitroacetophenone Preparation Products And Raw materials

Raw materials

Decanoic acid 2,2'-Azobis(2-methylpropionitrile) 2-Ethylnitrobenzene

Preparation Products

3-Nitroacetophenone
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2-Nitroacetophenone Suppliers

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View Lastest Price from 2-Nitroacetophenone manufacturers

Hebei Mujin Biotechnology Co.,Ltd
Product
2-Nitroacetophenone 577-59-3
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-06-27
Hebei Weibang Biotechnology Co., Ltd
Product
2-Nitroacetophenone 577-59-3
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-12-05
Hebei Chuanghai Biotechnology Co,.LTD
Product
2-Nitroacetophenone 577-59-3
Price
US $20.60/KG
Min. Order
1KG
Purity
99%
Supply Ability
5000kg
Release date
2024-08-09

577-59-3, 2-NitroacetophenoneRelated Search:

Methyl acrylate 4'-Bromoacetophenone 2',4'-Dichloroacetophenone L-PICEIN 2'-Hydroxyacetophenone Kresoxim-methyl 4'-Hydroxyacetophenone 4-Nitroacetophenone 2-Bromoacetophenone 2-Nitrophenylacetonitrile Acetophenone Methylparaben Dichloroacetonitrile Thiophanate-methyl 3-Nitroacetophenone Bensulfuron methyl 3-Aminoacetophenone 2-Nitrophenylacetic acid

  • Neighboring nitrobenzene ethyl ketone
  • 2’-nitro-acetophenon
  • AKOS BBS-00003220
  • 1-(2-nitrophenyl)ethanone
  • 2-NITROACETOPHENONE
  • LABOTEST-BB LT01895210
  • AURORA 14018
  • ETHANONE, 1-(2-NITROPHENYL)-
  • 1-(2-nitrophenyl)-ethanon
  • 2-Nitroacetophenone,97%
  • 1-(2-nitrophenyl)-Ethanone2-Nitroacetophenone
  • 2-nitro-1-phenylethanone
  • 2-Nitroacetophene
  • 1-Acetyl-2-nitrobenzene
  • o-Nitroacetophenone,95%
  • 1-(2-Nitrophenyl)ethan-1-one, 2-Acetylnitrobenzene
  • o-Nitroacetophenone, 95% 2.5GR
  • Methyl-o-nitrophenylketone
  • NSC 3641
  • o-nitroacetonphenone
  • 2-p-nitroacetophenone
  • 2'-Nitroacetophenone, 95+%
  • 2-acetylnitrobenzene
  • Acetophenone, 2'-nitro-
  • Methyl 2-nitrophenyl ketone
  • methyl2-nitrophenylketone
  • o-Acetylnitrobenzene
  • o-Nitro(acetyl)benzene
  • o-nitrophenyl methyl ketone
  • O-NITROACETOPHENONE
  • AKOS 233-65
  • 2'-Nitroacetophenone&gt
  • 2'-Nitroacetophne
  • 2'-Nitroacetophenone
  • 577-59-3
  • CH3COC6H4NO2
  • NO2C6H4COCH3
  • C8H7BNO3
  • KETONE
  • Building Blocks
  • C7 to C8
  • Carbonyl Compounds
  • Ketones
  • Organic Building Blocks
  • Aromatic Acetophenones & Derivatives (substituted)
  • Aromatics
  • Miscellaneous Reagents
  • C7 to C8
  • Carbonyl Compounds
  • Ketones
  • pharmaceutical intermediates
  • Carbonyl Compounds