ChemicalBook > CAS DataBase List > ARSENAZO III

ARSENAZO III

Product Name
ARSENAZO III
CAS No.
1668-00-4
Chemical Name
ARSENAZO III
Synonyms
NSC 91528;Arsenazo Ⅲ;Neothorine;ArzenazoⅢ;ARSEZO III;Arsenazo Il;Arsenazo-lll;ARSENAZO III;Arsenazo III,95%;Arsenazo III ,99%
CBNumber
CB9208234
Molecular Formula
C22H18As2N4O14S2
Formula Weight
776.37
MOL File
1668-00-4.mol
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ARSENAZO III Property

Melting point:
>320 °C(lit.)
bulk density
850kg/m3
storage temp. 
Store below +30°C.
solubility 
ammonium hydroxide: soluble1mg/mL
pka
-1.25±0.40(Predicted)
form 
Powder
color 
Brown
PH
2.3 (10g/l, H2O, 20℃)
λmax
569-576 nm (buffer pH 10.0)
BRN 
5717957
InChIKey
UQHVTNUJRKELCE-UHFFFAOYSA-N
SMILES
C1=C2C(C(O)=C(N=NC3=CC=CC=C3[As](O)(O)=O)C(S(O)(=O)=O)=C2)=C(O)C(N=NC2=CC=CC=C2[As](O)(O)=O)=C1S(O)(=O)=O
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Safety

Hazard Codes 
T,N
Risk Statements 
23/25-50/53
Safety Statements 
20/21-28-45-60-61
RIDADR 
UN 3465 6.1/PG 2
WGK Germany 
3
HS Code 
2931 90 00
HazardClass 
6.1(b)
PackingGroup 
III
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A92775
Product name
Arsenazo III
Purity
calcium-sensitive dye
Packaging
1g
Price
$97.4
Updated
2025/07/31
Sigma-Aldrich
Product number
A92775
Product name
Arsenazo III
Purity
calcium-sensitive dye
Packaging
5g
Price
$255
Updated
2025/07/31
Sigma-Aldrich
Product number
1.10107
Product name
Arsenazo III
Purity
metal indicator
Packaging
5G
Price
$1150
Updated
2025/07/31
TCI Chemical
Product number
A5009
Product name
Arsenazo III [Spectrophotometric reagent for U, Th, Zr and other metals, Indicator for the precipitation titration of SO4 with Ba]
Purity
>95.0%(T)
Packaging
1g
Price
$63
Updated
2025/07/31
TCI Chemical
Product number
A5009
Product name
Arsenazo III [Spectrophotometric reagent for U, Th, Zr and other metals, Indicator for the precipitation titration of SO4 with Ba]
Purity
>95.0%(T)
Packaging
5g
Price
$186
Updated
2025/07/31
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ARSENAZO III Chemical Properties,Usage,Production

Chemical Properties

Dark brown solid

Uses

Spectrophotometric reagent for U, Th, Zr and other metals.Indicator for the precipitation titration of SO4 with Ba.

Uses

Arsenazo III reacts with more than 30 metal ions to give coloured complexes. So far it has been utilized for the determination and detection of about 25 metal ions (including 16 rare earth metals). The majority of the analytical procedures are spectrophotometric.
The absorption spectra of the metal complexes of Arsenazo III possess two maxima at about 610 and 665 nm. Since the absorption of the reagent is very low at 665 nm, but is considerable at 610 nm, the extinction of the complexes at 665 nm is utilized for analytical purposes. At this wavelength the molar extinction coefficients of the complexes lie in the range 5 x 104—1.3 x 105. This explains the extremely high analytical sensitivity of the reagent. (Under optimum conditions the sensitivity may reach 0.01 γ/ml.).
The main advantage of Arsenazo III over Arsenazo I lies in the considerably higher stabilities of the complexes of the former. This makes possible the analytical utilization of the reagent in strong mineral acidic media. It gives complexes with tri- and tetravalent metal ions in acidic media where hydrolysis and the consequent formation of polynuclear species do not interfere with the analytically utilized reaction. Those metals whose complexes form only in solutions of higher pH do not interfere with the analytical determination of the metal ions giving complexes in strongly acidic media (thorium, zirconium, uranium, plutonium, neptunium, etc.). This is the reason of the relatively high analytical selectivity of Arsenazo III.
Trace amounts of zirconium can be enriched before determination by coprecipitation with titanium hydroxide. The titanium hydroxide precipitate containing the zirconium content of the sample is dissolved in 6 M hydrochloric acid solution and the zirconium determined photometrically with Arsenazo III. Thousand-fold amounts of titanium do not interfere with the determination of zirconium. The absorption maximum of the zirconium complex of Arsenazo III is at 665 nm.

Uses

Arsenazo III is usually used in the determination of calcium in serum,has been used to evaluate calcium transport in permeabilized cells,has also been used for the spectrophotometric determination of uranium and thorium.

Biological Activity

Arsenazo III is a metallochromic dye. Arsenazo III is used in the determination of calcium in biological samples. It is used to evaluate calcium transport in permeabilized cells. It is also used for the detection of rare earth metals (polyvalent metal ions). Arsenazo III is used for the spectrophotometric determination of uranium and thorium.

ARSENAZO III Preparation Products And Raw materials

Raw materials

Urea Sodium nitrite 1,8-Dihydroxynaphthylene-3,6-disulfonic acid Hydrochloric acid 2-Aminobenzenearsonic acid

Preparation Products

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ARSENAZO III Suppliers

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View Lastest Price from ARSENAZO III manufacturers

Chongqing Chemdad Co., Ltd
Product
ARSENAZO III 1668-00-4
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99
Supply Ability
20tons
Release date
2025-04-24
Shaanxi Dideu New Materials Co. Ltd
Product
ARSENAZO III 1668-00-4
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000KGS
Release date
2025-04-01
Henan Fengda Chemical Co., Ltd
Product
ARSENAZO III 1668-00-4
Price
US $36.00-1.60/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-03-25

1668-00-4, ARSENAZO IIIRelated Search:

o-Cresolphthalein Complexone tribroMoarsenazo Aluminon ZINCON Naphthalene ARSENAZO I URANIUM ARSENAZO III ARSENAZO III SODIUM PHENYLARSONIC ACID ARSENAZO III SODIUM SALT CARBOXYARSENAZO III ARSENAZO III ARSENAZO III DISODIUM SALT

  • 2,7-bis(2-Arsonophenylazo)-1,8-dihydroxynaphthalene-3,6-disulfonicacid,sodiumsalt
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  • 3,6-Bis(2-arsonophenylazo)-4,5-dihydroxy-2,7-naphthalenedisulfonic acid
  • 3,6-Bis(2-arsonophenylazo)-4,5-dihydroxynaphthalene-2,7-disulfonic acid
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  • 2,7-Bis(2-arsonophenylazo)chromotropic acid, Arsenazo III Beckman(R), 2,2μ-(1,8-Dihydroxy-3,6-disulfonaphthylene-2,7-bisazo)bisbenzenearsonic acid
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  • Arsenazo III [Spectrophotometric reagent for U, Th, Zr and other metals, Indicator for the precipitation titration of SO4 with Ba]&gt
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  • 1668-00-4
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