2-CHLORO-6-(TRIFLUOROMETHYL)BENZOTHIAZOLE
- Product Name
- 2-CHLORO-6-(TRIFLUOROMETHYL)BENZOTHIAZOLE
- CAS No.
- 159870-86-7
- Chemical Name
- 2-CHLORO-6-(TRIFLUOROMETHYL)BENZOTHIAZOLE
- Synonyms
- 2-CHLORO-6-(TRIFLUOROMETHYL)BENZOTHIAZOLE;2-chloro-6-(trifluoromethyl)benzo[d]thiazole;Benzothiazole, 2-chloro-6-(trifluoroMethyl)-;2-chloro-6-(trifluoroMethyl)-1,3-benzothiazole
- CBNumber
- CB9212806
- Molecular Formula
- C8H3ClF3NS
- Formula Weight
- 237.63
- MOL File
- 159870-86-7.mol
2-CHLORO-6-(TRIFLUOROMETHYL)BENZOTHIAZOLE Property
- Boiling point:
- 258℃
- Density
- 1.566
- Flash point:
- 110℃
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- -1.65±0.10(Predicted)
- Appearance
- Off-white to light brown Solid
Safety
- HS Code
- 29342000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- C432940
- Product name
- 2-Chloro-6-trifluoromethylbenzothiazole
- Packaging
- 100mg
- Price
- $85
- Updated
- 2021/12/16
- Product number
- 074058
- Product name
- 2-Chloro-6-trifluoromethylbenzothiazole
- Purity
- 95+%
- Packaging
- 500mg
- Price
- $185
- Updated
- 2021/12/16
- Product number
- 074058
- Product name
- 2-Chloro-6-trifluoromethylbenzothiazole
- Purity
- 95+%
- Packaging
- 1g
- Price
- $292
- Updated
- 2021/12/16
- Product number
- HCH0049528
- Product name
- 2-CHLORO-6-(TRIFLUOROMETHYL)BENZOTHIAZOLE
- Purity
- 95.00%
- Packaging
- 250MG
- Price
- $862.79
- Updated
- 2021/12/16
- Product number
- HCH0049528
- Product name
- 2-CHLORO-6-(TRIFLUOROMETHYL)BENZOTHIAZOLE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $1191.96
- Updated
- 2021/12/16
2-CHLORO-6-(TRIFLUOROMETHYL)BENZOTHIAZOLE Chemical Properties,Usage,Production
Chemical Properties
White solid
Uses
2-Chloro-6-trifluoromethylbenzothiazole
Synthesis
777-12-8
159870-86-7
The general procedure for the synthesis of 2-chloro-6-(trifluoromethyl)benzothiazole from 2-amino-6-(trifluoromethyl)benzothiazole was as follows: in a three-necked flask equipped with a condenser tube, copper chloride (370 mg, 2.75 mmol) was suspended in acetonitrile (5 mL), tert-butyl nitrite (0.41 mL, 3.44 mmol) was added, and the solution was stirred for 10 min at room temperature. Subsequently, a solution of 2-amino-6-trifluoromethylbenzothiazole (500 mg, 2.29 mmol) in acetonitrile (1 mL) was added slowly and dropwise. The reaction mixture was heated to 65 °C, maintained for 30 min and then cooled and diluted with excess 1N hydrochloric acid aqueous solution. The reaction mixture was extracted with ethyl acetate, the organic phase was separated, dried over anhydrous magnesium sulfate and concentrated under reduced pressure to give an orange semi-solid product (501 mg, 92% yield), which could be used in subsequent reactions without further purification. The product was identified by 1H NMR (300 MHz, CDCl3): δ 8.10-8.05 (m, 2H), 7.74 (d, 1H); LC-MS detection showed m/z 238.2 (MH+) with a retention time of 3.76 min; and TLC analysis showed an Rf value of 0.50 (unfolding reagent ratio of hexane/ethyl acetate 9:1).
References
[1] Patent: US2004/224997, 2004, A1. Location in patent: Page 30
[2] Patent: WO2007/39176, 2007, A1. Location in patent: Page/Page column 67-68
2-CHLORO-6-(TRIFLUOROMETHYL)BENZOTHIAZOLE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-CHLORO-6-(TRIFLUOROMETHYL)BENZOTHIAZOLE manufacturers
- Product
- 2-Chloro-6-trifluoromethylbenzothiazole 159870-86-7
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99.1%
- Supply Ability
- 100 tons
- Release date
- 2022-01-14
- Product
- 2-CHLORO-6-(TRIFLUOROMETHYL)BENZOTHIAZOLE 159870-86-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- Customized
- Release date
- 2019-07-03