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2-CHLORO-6-(TRIFLUOROMETHYL)BENZOTHIAZOLE

Product Name
2-CHLORO-6-(TRIFLUOROMETHYL)BENZOTHIAZOLE
CAS No.
159870-86-7
Chemical Name
2-CHLORO-6-(TRIFLUOROMETHYL)BENZOTHIAZOLE
Synonyms
2-CHLORO-6-(TRIFLUOROMETHYL)BENZOTHIAZOLE;2-chloro-6-(trifluoromethyl)benzo[d]thiazole;Benzothiazole, 2-chloro-6-(trifluoroMethyl)-;2-chloro-6-(trifluoroMethyl)-1,3-benzothiazole
CBNumber
CB9212806
Molecular Formula
C8H3ClF3NS
Formula Weight
237.63
MOL File
159870-86-7.mol
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2-CHLORO-6-(TRIFLUOROMETHYL)BENZOTHIAZOLE Property

Boiling point:
258℃
Density 
1.566
Flash point:
110℃
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
-1.65±0.10(Predicted)
Appearance
Off-white to light brown Solid
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Safety

HS Code 
29342000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
C432940
Product name
2-Chloro-6-trifluoromethylbenzothiazole
Packaging
100mg
Price
$85
Updated
2021/12/16
Matrix Scientific
Product number
074058
Product name
2-Chloro-6-trifluoromethylbenzothiazole
Purity
95+%
Packaging
500mg
Price
$185
Updated
2021/12/16
Matrix Scientific
Product number
074058
Product name
2-Chloro-6-trifluoromethylbenzothiazole
Purity
95+%
Packaging
1g
Price
$292
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0049528
Product name
2-CHLORO-6-(TRIFLUOROMETHYL)BENZOTHIAZOLE
Purity
95.00%
Packaging
250MG
Price
$862.79
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0049528
Product name
2-CHLORO-6-(TRIFLUOROMETHYL)BENZOTHIAZOLE
Purity
95.00%
Packaging
1G
Price
$1191.96
Updated
2021/12/16
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2-CHLORO-6-(TRIFLUOROMETHYL)BENZOTHIAZOLE Chemical Properties,Usage,Production

Chemical Properties

White solid

Uses

2-Chloro-6-trifluoromethylbenzothiazole

Synthesis

777-12-8

159870-86-7

The general procedure for the synthesis of 2-chloro-6-(trifluoromethyl)benzothiazole from 2-amino-6-(trifluoromethyl)benzothiazole was as follows: in a three-necked flask equipped with a condenser tube, copper chloride (370 mg, 2.75 mmol) was suspended in acetonitrile (5 mL), tert-butyl nitrite (0.41 mL, 3.44 mmol) was added, and the solution was stirred for 10 min at room temperature. Subsequently, a solution of 2-amino-6-trifluoromethylbenzothiazole (500 mg, 2.29 mmol) in acetonitrile (1 mL) was added slowly and dropwise. The reaction mixture was heated to 65 °C, maintained for 30 min and then cooled and diluted with excess 1N hydrochloric acid aqueous solution. The reaction mixture was extracted with ethyl acetate, the organic phase was separated, dried over anhydrous magnesium sulfate and concentrated under reduced pressure to give an orange semi-solid product (501 mg, 92% yield), which could be used in subsequent reactions without further purification. The product was identified by 1H NMR (300 MHz, CDCl3): δ 8.10-8.05 (m, 2H), 7.74 (d, 1H); LC-MS detection showed m/z 238.2 (MH+) with a retention time of 3.76 min; and TLC analysis showed an Rf value of 0.50 (unfolding reagent ratio of hexane/ethyl acetate 9:1).

References

[1] Patent: US2004/224997, 2004, A1. Location in patent: Page 30
[2] Patent: WO2007/39176, 2007, A1. Location in patent: Page/Page column 67-68

2-CHLORO-6-(TRIFLUOROMETHYL)BENZOTHIAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-CHLORO-6-(TRIFLUOROMETHYL)BENZOTHIAZOLE Suppliers

China 86 Germany 1 India 1 Switzerland 1 United Kingdom 1 United States 8 Global 98
Achemica
Tel
--
Fax
--
Email
contact@achemica.com
Country
Switzerland
ProdList
6155
Advantage
50
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View Lastest Price from 2-CHLORO-6-(TRIFLUOROMETHYL)BENZOTHIAZOLE manufacturers

Honest Joy Holdings Limited
Product
2-Chloro-6-trifluoromethylbenzothiazole 159870-86-7
Price
US $0.00/KG
Min. Order
1KG
Purity
99.1%
Supply Ability
100 tons
Release date
2022-01-14
Career Henan Chemical Co
Product
2-CHLORO-6-(TRIFLUOROMETHYL)BENZOTHIAZOLE 159870-86-7
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
Customized
Release date
2019-07-03

159870-86-7, 2-CHLORO-6-(TRIFLUOROMETHYL)BENZOTHIAZOLERelated Search:

ETHYL 2-CHLORO-6-HYDROXYBENZOATE 2-Chloro-6-nitropyridine 6-CHLORO-2-HYDROXYPYRAZINE METHYL 2-CHLORO-6-METHOXYPYRIDINE-4-CARBOXYLATE 2-CHLORO-6-METHOXY-4-PYRIDINECARBOXALDEHYDE 2-Chloro-6-cyanobenzothiazole 2-CHLORO-6-METHOXYBENZONITRILE 2-Chloro-6-methoxybenzothiazole 2-Chloro-6-nitrobenzothiazole 2-Chloro-6-(trifluoromethoxy)-benzothiazole 2-Chloro-4-methylbenzothiazole 2-CHLORO-6-ETHOXY-1,3-BENZOTHIAZOLE 2-Mercaptobenzothiazole Benzothiazole, 2-chloro-5-methyl- (7CI,8CI,9CI) 3-Chloro-2-aminoanisole 2-Chloro-6-methylbenzothiazole 6-TRIFLUOROMETHYLBENZOTHIAZOLE 2-CHLORO-6-(TRIFLUOROMETHYL)BENZOTHIAZOLE

  • 2-CHLORO-6-(TRIFLUOROMETHYL)BENZOTHIAZOLE
  • 2-chloro-6-(trifluoromethyl)benzo[d]thiazole
  • 2-chloro-6-(trifluoroMethyl)-1,3-benzothiazole
  • Benzothiazole, 2-chloro-6-(trifluoroMethyl)-
  • 159870-86-7