Uses Synthesis
ChemicalBook > CAS DataBase List > methyl 2-chloropyrimidine-4-carboxylate

methyl 2-chloropyrimidine-4-carboxylate

Uses Synthesis
Product Name
methyl 2-chloropyrimidine-4-carboxylate
CAS No.
149849-94-5
Chemical Name
methyl 2-chloropyrimidine-4-carboxylate
Synonyms
oropyrimidine-4-carboxyL;4-PyriMidinecarboxylic ac...;2-Chloro-4-(methoxycarbonyl)pyrimidine;methyl 2-chloropyrimidine-4-carboxylate;2-Chloro-4-pyrimidinecarboxylate methyl ester;2-chloro-4-Pyrimidinecarboxylic acid methyl ester;2-Chloro-pyrimidin-4-carboxylic acid methyl ester;2-Chloro-pyriMidine-4-carboxylic acid Methyl ester;4-PyriMidinecarboxylic acid, 2-chloro-, Methyl ester;2-chloro-4-Pyrimidinecarboxylic acid methyl ester (9CI ACI)
CBNumber
CB92129364
Molecular Formula
C6H5ClN2O2
Formula Weight
172.57
MOL File
149849-94-5.mol
More
Less

methyl 2-chloropyrimidine-4-carboxylate Property

Boiling point:
304.3±15.0 °C(Predicted)
Density 
1.372±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
-3.78±0.20(Predicted)
form 
solid
Appearance
Off-white to light yellow Solid
InChI
InChI=1S/C6H5ClN2O2/c1-11-5(10)4-2-3-8-6(7)9-4/h2-3H,1H3
InChIKey
GGTNGWOGJHJQCL-UHFFFAOYSA-N
SMILES
C1(Cl)=NC=CC(C(OC)=O)=N1
More
Less

Safety

Risk Statements 
36/37/38
Safety Statements 
36/37/39
WGK Germany 
3
HS Code 
29335990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
796794
Product name
2-Chloropyrimidine-4-carboxylic acid methyl ester
Purity
95%
Packaging
1g
Price
$100
Updated
2023/06/20
TRC
Product number
M295758
Product name
Methyl2-chloropyrimidine-4-carboxylate
Packaging
250mg
Price
$55
Updated
2021/12/16
Matrix Scientific
Product number
074038
Product name
Methyl 2-chloropyrimidine-4-carboxylate
Purity
95+%
Packaging
500mg
Price
$32
Updated
2021/12/16
Matrix Scientific
Product number
074038
Product name
Methyl 2-chloropyrimidine-4-carboxylate
Purity
95+%
Packaging
1g
Price
$49
Updated
2021/12/16
AK Scientific
Product number
J98935
Product name
Methyl2-chloropyrimidine-4-carboxylate
Packaging
5g
Price
$150
Updated
2021/12/16
More
Less

methyl 2-chloropyrimidine-4-carboxylate Chemical Properties,Usage,Production

Uses

Methyl 2-chloropyrimidine-4-carboxylate is an organic ester, which can be used as an intermediate in pharmaceutical synthesis for experimental research and pharmaceutical synthesis.

Synthesis

Synthesis of methyl 2-chloropyrimidine-4-carboxylate: 2-chloropyrimidine-4-carboxylic acid (4.76 g, 30 mmol) was dissolved in dichloromethane (30 mL) and dimethylformamide (0.3 mL), to which was added Slowly add oxalyl chloride (5.72g, 45mmol) dropwise, stir at room temperature for 2 hours, Chemicalbook, after concentrating to an appropriate volume, add dropwise to anhydrous methanol (50mL) placed under ice bath conditions, after the dropwise addition, the reaction is transferred to The reaction was carried out at room temperature for 2 hours, and concentrated under reduced pressure to obtain (5.17 g, yield 100%).

References

[1] Patent: US2007/225271, 2007, A1. Location in patent: Page/Page column 33

methyl 2-chloropyrimidine-4-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

methyl 2-chloropyrimidine-4-carboxylate Suppliers

Belgium 1 China 164 France 1 India 1 United Kingdom 1 United States 20 Global 188
Nanjing ShinGen PharmTech Co.，Ltd
Tel
15365085396
Email
523576380@qq.com
Country
China
ProdList
560
Advantage
58
Shandong Baiqi Biomedical Co. Ltd
Tel
0536-8998390 13173160180
Email
sales@baiqpharm.com
Country
China
ProdList
584
Advantage
58
Aikon International Limited
Tel
025-66113011 13155353615
Fax
(7)02557626880
Email
qzhang@aikonchem.com
Country
China
ProdList
15394
Advantage
58
SiChuang NanBu Honesty Technology Co., Ltd.
Tel
0838-5675166 15883665058
Fax
0838-5675535
Email
nbcxkj@126.com
Country
China
ProdList
919
Advantage
55
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
Tel
0311-89250318 031166536426
Fax
4000311741
Email
master@sjzsdyn.com
Country
China
ProdList
2805
Advantage
65
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14101
Advantage
59
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11035
Advantage
64
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
16077
Advantage
64
EnciPharmatech Co., Ltd
Tel
025-52714267-66 13813902930
Fax
86 025 52714266
Email
stephen_shengll@hotmail.com
Country
China
ProdList
232
Advantage
64
Shanghai Ennopharm Co., Ltd.
Tel
+86 (21) 6435-5022
Country
China
ProdList
4267
Advantage
65
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
18270980682
Fax
021 51613951
Email
mlcheng@sunwaypharm.cn
Country
China
ProdList
8669
Advantage
57
Hunan Hui Bai Shi Biotechnology Co., Ltd.
Tel
0731-85526065 13308475853
Email
ivy@hnhbsj.com
Country
China
ProdList
7247
Advantage
62
Heterochem
Tel
027-88041443 13072715837
Fax
027-51829379
Email
sales@hetero-chem.com
Country
China
ProdList
696
Advantage
58
Acorn PharmaTech Co., Ltd.
Tel
025-58395930
Fax
025-5861-9182
Email
sales@acornpharma.com
Country
China
ProdList
982
Advantage
60
Hangzhou Sage Chemical Co., Ltd.
Tel
+86057186818502 13588463833
Fax
Pls mail us for more information!
Email
info@sagechem.com
Country
China
ProdList
10266
Advantage
58
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9510
Advantage
58
Shanghai Jian Chao Chemical Technology Co., Ltd.
Tel
150-2103-5486 18017383231
Fax
qq：2817624287
Email
983544897@qq.com
Country
China
ProdList
9342
Advantage
55
Nantong Ayeschem Co., Ltd
Tel
+86-513-86760116
Fax
+86-513-86760116;
Email
sales@ayeschem.com
Country
China
ProdList
99
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
Advantage
55
Acesys Pharmatech
Tel
18860950986
Email
tangmanman@zenjipharma.com
Country
China
ProdList
1733
Advantage
55
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9899
Advantage
55
Chem-Stone Co.,Ltd.
Tel
020-82185713,82185709 13418171485
Fax
020-82185696
Email
sales@chem-stone.com
Country
China
ProdList
744
Advantage
56
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9979
Advantage
55
Shanghai Worldyang Chemical Co.,Ltd.
Tel
021-021-56795766
Fax
+86-21-56795266
Email
sales@worldyachem.com
Country
China
ProdList
9476
Advantage
58
Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883
Fax
0731-82251112
Email
sales@huatengsci.com
Country
China
ProdList
5872
Advantage
58
Suzhou ChemWe Chemical Co., Ltd.
Tel
512-62706911 13401923197
Fax
0512-62706910
Email
sales@chemwe.com
Country
China
ProdList
94
Advantage
56
Hangzhou J&H Chemical Co., Ltd.
Tel
0571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
14912
Advantage
59
Shanghai HuanChuan Industry Co.,Ltd.
Tel
021-61478794
Fax
021-61478794
Email
sales@hcshhai.com
Country
China
ProdList
9793
Advantage
50
Shanghai Jovan Biochemical Technology Co. Ltd.
Tel
+86-021-61654350
Fax
+86-021-61654350
Email
1245958370@qq.com
Country
China
ProdList
2982
Advantage
50
Shanghai Song Yuan Chemical Technology Co., Ltd.
Tel
010-1234567 18521000990
Fax
86-021-33275113
Email
sonyuanchemical@163.com
Country
China
ProdList
6479
Advantage
50
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12346
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51395
Advantage
80
Bellen Chemistry Co., Ltd.
Tel
010-60400365-8001 15910885229
Fax
010-60400361
Email
service@bellenchem.com
Country
China
ProdList
4514
Advantage
60
JW & Y Pharmlab Co., Ltd.
Tel
021-64340559 13651849907;
Fax
021- 64345308
Email
xinyu_shi@jwypharmlab.com.cn
Country
China
ProdList
12000
Advantage
58
SPIRO PHARMA
Tel
Fax
-
Email
eric_feng1954@126.com
Country
China
ProdList
9248
Advantage
55
Chengdu Research Accelerators Technology Co., Ltd.
Tel
028-64353063
Fax
028-64353063 QQ:784253935
Email
reacchemical@163.com
Country
China
ProdList
5253
Advantage
58
Zhengzhou Alfachem Co., Ltd.
Tel
0371-53765687 18937137882
Fax
QQ:2885373884
Email
2853979813@qq.com
Country
China
ProdList
7991
Advantage
55
shandong XuanHong Pharmaceutical Technology Co.,Ltd
Tel
+86-0531-88801869 15090917080
Fax
0531-88801867
Email
sciencechem@163.com
Country
China
ProdList
293
Advantage
55
ShangHai Siyan Biological Technology Co., Ltd.
Tel
021-50908862，442785678，326799392 18721037013
Fax
021-50908862
Email
siyansales@126.com
Country
China
ProdList
9627
Advantage
58
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
Tel
0311-89250318 031166536426
Fax
4000311741
Email
master@sjzsdyn.com
Country
China
ProdList
3495
Advantage
58
Nanjing YaoCheng Pharmaceutical Co., Ltd.
Tel
025-57043319 15261831516
Fax
025-57043319
Email
307514552@qq.com
Country
China
ProdList
251
Advantage
50
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Changzhou Hopschain Chemical Co.,Ltd.
Tel
0519-85528066 13775048983
Fax
0519-85528066
Email
sales@hopschem.com
Country
China
ProdList
31553
Advantage
55
parabiochem
Tel
025-83453382-8005
Fax
025-83453382
Email
sale@parabiochem.com
Country
China
ProdList
9595
Advantage
55
Shandong Xiya Chemical Co., Ltd.
Tel
4009903999 13395398332
Fax
0539-6365991
Email
sales@xiyashiji.com
Country
China
ProdList
20794
Advantage
60
Chengdu Xiaojia Technology Co., Ltd.
Tel
15902830537
Email
zhanghao@happysyn.com
Country
China
ProdList
3180
Advantage
55
Suzhou JingTong Pharmaceutical Co., Ltd.
Tel
13675155016
Fax
18912765016
Email
tongtf110@sina.com
Country
China
ProdList
963
Advantage
55
Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-0371-55629727 13323845623
Fax
037155629727
Email
2885676761@qq.com
Country
China
ProdList
10110
Advantage
58
More
Less

View Lastest Price from methyl 2-chloropyrimidine-4-carboxylate manufacturers

Honest Joy Holdings Limited
Product
Methyl 2-chloropyrimidine-4- carboxylate 149849-94-5
Price
US $0.00/KG
Min. Order
1KG
Purity
98.5%
Supply Ability
100 tons
Release date
2022-02-08
Zhuozhou Wenxi import and Export Co., Ltd
Product
methyl 2-chloropyrimidine-4-carboxylate 149849-94-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
methyl 2-chloropyrimidine-4-carboxylate 149849-94-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08

149849-94-5, methyl 2-chloropyrimidine-4-carboxylateRelated Search:

2-Chloropyrimidine 2,4,5-Trichloropyrimidine Trichloropyrimidine 5-Chloropyrimidine PYRIMIDINE-4-CARBOXYLIC ACID METHYL ESTER

  • methyl 2-chloropyrimidine-4-carboxylate
  • 2-Chloro-4-(methoxycarbonyl)pyrimidine
  • 4-PyriMidinecarboxylic acid, 2-chloro-, Methyl ester
  • 4-PyriMidinecarboxylic ac...
  • 2-Chloro-pyriMidine-4-carboxylic acid Methyl ester
  • 2-Chloro-4-(methoxycarbonyl)pyrimidine, 2-Chloro-4-(methoxycarbonyl)-1,3-diazine
  • 2-Chloro-pyrimidin-4-carboxylic acid methyl ester
  • 2-chloro-4-Pyrimidinecarboxylic acid methyl ester
  • oropyrimidine-4-carboxyL
  • 4-Pyrimidinecarboxylic acid, 2-chloro-, methyl ester (9CI, ACI)
  • 2-chloro-4-Pyrimidinecarboxylic acid methyl ester (9CI ACI)
  • 2-Chloro-4-pyrimidinecarboxylate methyl ester
  • 149849-94-5
  • Heterocycle-Pyrimidine series