Uses Synthesis
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methyl 2-chloropyrimidine-4-carboxylate

Uses Synthesis
Product Name
methyl 2-chloropyrimidine-4-carboxylate
CAS No.
149849-94-5
Chemical Name
methyl 2-chloropyrimidine-4-carboxylate
Synonyms
oropyrimidine-4-carboxyL;4-PyriMidinecarboxylic ac...;2-Chloro-4-(methoxycarbonyl)pyrimidine;methyl 2-chloropyrimidine-4-carboxylate;2-chloro-4-Pyrimidinecarboxylic acid methyl ester;2-Chloro-pyrimidin-4-carboxylic acid methyl ester;2-Chloro-pyriMidine-4-carboxylic acid Methyl ester;4-PyriMidinecarboxylic acid, 2-chloro-, Methyl ester;2-chloro-4-Pyrimidinecarboxylic acid methyl ester (9CI ACI);4-Pyrimidinecarboxylic acid, 2-chloro-, methyl ester (9CI, ACI)
CBNumber
CB92129364
Molecular Formula
C6H5ClN2O2
Formula Weight
172.57
MOL File
149849-94-5.mol
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methyl 2-chloropyrimidine-4-carboxylate Property

Boiling point:
304.3±15.0 °C(Predicted)
Density 
1.372±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
solid
pka
-3.78±0.20(Predicted)
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Safety

Risk Statements 
36/37/38
Safety Statements 
36/37/39
WGK Germany 
3
HS Code 
29335990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
796794
Product name
2-Chloropyrimidine-4-carboxylic acid methyl ester
Purity
95%
Packaging
1g
Price
$100
Updated
2023/06/20
TRC
Product number
M295758
Product name
Methyl2-chloropyrimidine-4-carboxylate
Packaging
250mg
Price
$55
Updated
2021/12/16
AK Scientific
Product number
J98935
Product name
Methyl2-chloropyrimidine-4-carboxylate
Packaging
5g
Price
$150
Updated
2021/12/16
Apolloscientific
Product number
OR45090
Product name
Methyl2-chloropyrimidine-4-carboxylate
Packaging
1g
Price
$182
Updated
2021/12/16
Matrix Scientific
Product number
074038
Product name
Methyl 2-chloropyrimidine-4-carboxylate
Purity
95+%
Packaging
5g
Price
$199
Updated
2021/12/16
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methyl 2-chloropyrimidine-4-carboxylate Chemical Properties,Usage,Production

Uses

Methyl 2-chloropyrimidine-4-carboxylate is an organic ester, which can be used as an intermediate in pharmaceutical synthesis for experimental research and pharmaceutical synthesis.

Synthesis

Synthesis of methyl 2-chloropyrimidine-4-carboxylate: 2-chloropyrimidine-4-carboxylic acid (4.76 g, 30 mmol) was dissolved in dichloromethane (30 mL) and dimethylformamide (0.3 mL), to which was added Slowly add oxalyl chloride (5.72g, 45mmol) dropwise, stir at room temperature for 2 hours, Chemicalbook, after concentrating to an appropriate volume, add dropwise to anhydrous methanol (50mL) placed under ice bath conditions, after the dropwise addition, the reaction is transferred to The reaction was carried out at room temperature for 2 hours, and concentrated under reduced pressure to obtain (5.17 g, yield 100%).

methyl 2-chloropyrimidine-4-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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methyl 2-chloropyrimidine-4-carboxylate Suppliers

Ambinter
Tel
--
Fax
--
Email
contact@ambinter.com
Country
France
ProdList
1648
Advantage
60
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View Lastest Price from methyl 2-chloropyrimidine-4-carboxylate manufacturers

Honest Joy Holdings Limited
Product
Methyl 2-chloropyrimidine-4- carboxylate 149849-94-5
Price
US $0.00/KG
Min. Order
1KG
Purity
98.5%
Supply Ability
100 tons
Release date
2022-02-08
Zhuozhou Wenxi import and Export Co., Ltd
Product
methyl 2-chloropyrimidine-4-carboxylate 149849-94-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
methyl 2-chloropyrimidine-4-carboxylate 149849-94-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08

149849-94-5, methyl 2-chloropyrimidine-4-carboxylateRelated Search:


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  • 2-Chloro-pyrimidin-4-carboxylic acid methyl ester
  • 2-chloro-4-Pyrimidinecarboxylic acid methyl ester
  • oropyrimidine-4-carboxyL
  • 4-Pyrimidinecarboxylic acid, 2-chloro-, methyl ester (9CI, ACI)
  • 2-chloro-4-Pyrimidinecarboxylic acid methyl ester (9CI ACI)
  • 149849-94-5
  • Heterocycle-Pyrimidine series