DCPIB

Product Name: DCPIB
CAS No.: 82749-70-0
Chemical Name: DCPIB
Synonyms: DCPIB;4-(2-BUTYL-6,7-DICHLORO-2-CYCLOPENTYLINDAN-1-ON-5-YL)OXYBUTYRIC ACID;4-(2-butyl-6,7-dichlor-2-cyclopentyl-indan-1-on-5-yl) oxybutyric acid;4-[(2-Butyl-6,7-dichloro-2-cyclopentyl-1-oxo-5-indanyl)oxy]butanoic Acid;4-[(2-BUTYL-6,7-DICHLORO-2-CYCLOPENTYL-2,3-DIHYDRO-1-OXO-1H-INDEN-5-YL)OXY]BUTANOIC ACID;Butanoic acid, 4-[(2-butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-1-oxo-1H-inden-5-yl)oxy]-;Cl-Channels,Chloride Channel,cardiomyocytes,DCPIB,ischemia,COS-7,KcsA,Potassium Channel,CPAE cell,Inhibitor,inhibit,swelling,rMCAO
CBNumber: CB9215009
Molecular Formula: C22H28Cl2O4
Formula Weight: 427.36
MOL File: 82749-70-0.mol

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DCPIB Property

Boiling point:: 593.8±50.0 °C(Predicted)
Density: 1.262±0.06 g/cm3(Predicted)
storage temp.: Store at +4°C
solubility: insoluble in H2O; ≥49.8 mg/mL in EtOH; ≥50.8 mg/mL in DMSO
form: solid
pka: 4.53±0.10(Predicted)
color: White

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Safety

Hazard Codes: T
Risk Statements: 25-41
Safety Statements: 26-36/39-45

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H318Causes serious eye damage

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Tocris

Product number: 1540
Product name: DCPIB
Purity: ≥98%(HPLC)
Packaging: 50
Price: $675
Updated: 2021/12/16

Tocris

Product number: 1540
Product name: DCPIB
Purity: ≥98%(HPLC)
Packaging: 10
Price: $160
Updated: 2021/12/16

TRC

Product number: D195150
Product name: DCPIB
Packaging: 100mg
Price: $1105
Updated: 2021/12/16

Usbiological

Product number: 255115
Product name: DCPIB
Packaging: 10mg
Price: $403
Updated: 2021/12/16

ChemScene

Product number: CS-0027766
Product name: DCPIB
Purity: 99.81%
Packaging: 50mg
Price: $550
Updated: 2021/12/16

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DCPIB Chemical Properties,Usage,Production

Uses

DCPIB is a potent, selective blocker of the volume-sensitive anion channel (VSAC) in rat pancreatic β-cells.

Definition

ChEBI: 4-[(2-butyl-6,7-dichloro-2-cyclopentyl-1-oxo-3H-inden-5-yl)oxy]butanoic acid is a member of indanones.

Biological Activity

Potent, selective blocker of the volume-sensitive anion channel (VSAC) in rat pancreatic β -cells (IC 50 ~ 2 μ M) and I Cl,swell in various cardiovascular tissues (IC 50 = 4.1 μ M in CPAE cells); blockade is voltage-independent. Displays minimal inhibition of other Cl - and K + currents (< 10% inhibition at 10 μ M). Inhibits glucose-stimulated insulin secretion in intact β -cells via VSAC inhibition and indirect K ATP channel activation. Reverses cell swelling-induced action potential duration shortening in atrial myocytes and inhibits astroglial swelling in vitro .

storage

Store at +4°C

DCPIB Preparation Products And Raw materials

Raw materials

Preparation Products

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DCPIB Suppliers

China 44 Germany 2 Switzerland 1 United Kingdom 2 United States 9 Global 58

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15848
Advantage: 69

Zhengzhou HSH Science & Technology Co., Ltd.

Tel: 0371-55932928 18937192232
Fax: 0086-0371-55932928
Email: 1282296214@qq.com
Country: China
ProdList: 496
Advantage: 55

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4153
Advantage: 55

Guangzhou Zhiya Chemdrugs Co.,Ltd

Tel: 18122150900
Fax: QQ:2869377561
Email: sculk28@163.com
Country: China
ProdList: 646
Advantage: 55

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8449
Advantage: 60

ShangHai Biochempartner Co.,Ltd

Tel: 17754423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8011
Advantage: 62

Shanghai Chaolan Chemical Technology Center

Tel: QQ:65489617 15618227136
Fax: 21-5161 9052
Email: info@SuperLan-chem.com
Country: China
ProdList: 9756
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 19892
Advantage: 58

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6393
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Career Henan Chemica Co

Tel: +86-0371-86658258 15093356674;
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30255
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82749-70-0, DCPIBRelated Search:

2,3-Dichloro-4-hydroxybenzaldehyde 6-CHLORO-1-INDANONE 96 7-CHLORO-1-INDANONE 2-CHLORO-4,5-DIMETHYLPHENOL 4-(3-CHLORO-PHENOXY)-BUTYRIC ACID 2'-CHLORO-2,2-DIMETHYLBUTYROPHENONE 2',3'-DICHLORO-2,2-DIMETHYLBUTYROPHENONE 2-PENTYL-1-INDANONE 1-(3-chloro-4-ethoxyphenyl)ethanone DCPIB 1-(3-CHLORO-4-PROPOXYPHENYL)-ETHANONE 3'-CHLORO-2,2-DIMETHYLBUTYROPHENONE 2'-CHLORO-2,2-DIMETHYLPROPIOPHENONE 2',3'-DICHLORO-2,2-DIMETHYLPROPIOPHENONE 2,2-DIMETHYL-4'-METHOXYBUTYROPHENONE 4-(4-ACETYL-PHENOXY)-BUTYRIC ACID 1-(4-methoxyphenyl)-2,2-dimethyl-propan-1-one 3'-CHLORO-2,2-DIMETHYLPROPIOPHENONE

DCPIB

4-[(2-BUTYL-6,7-DICHLORO-2-CYCLOPENTYL-2,3-DIHYDRO-1-OXO-1H-INDEN-5-YL)OXY]BUTANOIC ACID

4-(2-BUTYL-6,7-DICHLORO-2-CYCLOPENTYLINDAN-1-ON-5-YL)OXYBUTYRIC ACID

Butanoic acid, 4-[(2-butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-1-oxo-1H-inden-5-yl)oxy]-

Cl-Channels,Chloride Channel,cardiomyocytes,DCPIB,ischemia,COS-7,KcsA,Potassium Channel,CPAE cell,Inhibitor,inhibit,swelling,rMCAO

4-(2-butyl-6,7-dichlor-2-cyclopentyl-indan-1-on-5-yl) oxybutyric acid

4-[(2-Butyl-6,7-dichloro-2-cyclopentyl-1-oxo-5-indanyl)oxy]butanoic Acid

82749-70-0

Chloride channel