ChemicalBook > CAS DataBase List > 3-[3-[N-(2-CHLORO-3-TRIFLUOROMETHYLBENZYL)-(2,2-DIPHENYLETHYL)AMINO]PROPYLOXY]PHENYLACETIC ACID HYDROCHLORIDE
3-[3-[N-(2-CHLORO-3-TRIFLUOROMETHYLBENZYL)-(2,2-DIPHENYLETHYL)AMINO]PROPYLOXY]PHENYLACETIC ACID HYDROCHLORIDE
- Product Name
- 3-[3-[N-(2-CHLORO-3-TRIFLUOROMETHYLBENZYL)-(2,2-DIPHENYLETHYL)AMINO]PROPYLOXY]PHENYLACETIC ACID HYDROCHLORIDE
- CAS No.
- 405911-09-3
- Chemical Name
- 3-[3-[N-(2-CHLORO-3-TRIFLUOROMETHYLBENZYL)-(2,2-DIPHENYLETHYL)AMINO]PROPYLOXY]PHENYLACETIC ACID HYDROCHLORIDE
- Synonyms
- GW3965;CS-1391;GW3965 (GW 3965;GW 3965 HYDROCHLORIDE;2-(3-(3-((2-Chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)-amino)propoxy)phenyl)acetic a;2-(3-(3-((2-Chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)-amino)propoxy)phenyl)acetic acid;Benzeneacetic acid,3-[3-[[[2-chloro-3-(trifluoromethyl)phenyl]methyl](2,2-diphenylethyl)amino]propoxy]-;3-[3-[N-(2-CHLORO-3-TRIFLUOROMETHYLBENZYL)-(2,2-DIPHENYLETHYL)AMINO]PROPYLOXY]PHENYLACETIC ACID HYDROCHLORIDE;3-[3-[n-(2-chloro-3-trifluoroMethylbenzyl)-(2,2-diphenylethyl)aMino]propvloxy]phenylacetic acid hydrochloride;3-[3-[[[2-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]METHYL](2,2-DIPHENYLETHYL)AMINO]PROPOXY]BENZENEACETIC ACID HYDROCHLORIDE
- CBNumber
- CB9217997
- Molecular Formula
- C33H31ClF3NO3
- Formula Weight
- 582.05
- MOL File
- 405911-09-3.mol
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3-[3-[N-(2-CHLORO-3-TRIFLUOROMETHYLBENZYL)-(2,2-DIPHENYLETHYL)AMINO]PROPYLOXY]PHENYLACETIC ACID HYDROCHLORIDE Property
- Melting point:
- 174-179°C
- Boiling point:
- 672.4±55.0 °C(Predicted)
- Density
- 1.261±0.06 g/cm3(Predicted)
- storage temp.
- Desiccate at RT
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 4.18±0.10(Predicted)
- color
- White to Off-White
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H318Causes serious eye damage
H413May cause long lasting harmful effects to aquatic life
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P501Dispose of contents/container to..…
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N-Bromosuccinimide Price
Tocris
- Product number
- 2474
- Product name
- GW3965 hydrochloride
- Purity
- ≥98%(HPLC)
- Packaging
- 1
- Price
- $131
- Updated
- 2021/12/16
Tocris
- Product number
- 2474
- Product name
- GW3965 hydrochloride
- Purity
- ≥98%(HPLC)
- Packaging
- 10
- Price
- $280
- Updated
- 2021/12/16
TRC
- Product number
- G931050
- Product name
- GW3965
- Packaging
- 50mg
- Price
- $470
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- BRS0000146
- Product name
- GW 3965
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $505
- Updated
- 2021/12/16
Matrix Scientific
- Product number
- 094369
- Product name
- 2-(3-(3-((2-Chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)-amino)propoxy)phenyl)acetic acid hydrochloride
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $2268
- Updated
- 2021/12/16
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3-[3-[N-(2-CHLORO-3-TRIFLUOROMETHYLBENZYL)-(2,2-DIPHENYLETHYL)AMINO]PROPYLOXY]PHENYLACETIC ACID HYDROCHLORIDE Chemical Properties,Usage,Production
Uses
GW3965 can be used in biological study of effect of liver X receptor agonists, T0901317 and GW3965 treatment on cholesterol efflux and apoptosis in human CAL-1 and GEN2.2 blastic plasmacytoid dendritic cell neoplasm cells.
Definition
ChEBI: GW 3965 is a diarylmethane.
Biological Activity
Selective, orally active non-steroidal agonist for the liver X receptor (LXR). In cell-based reporter gene assays, acts as a full agonist of hLXR α and hLXR β (EC 50 values are 190 and 30 nM respectively). Up-regulates ABCA1 gene expression and raises circulating HDL levels. Displays potent antiatherogenic activity in mouse models of atherosclerosis.
target
LXRα
3-[3-[N-(2-CHLORO-3-TRIFLUOROMETHYLBENZYL)-(2,2-DIPHENYLETHYL)AMINO]PROPYLOXY]PHENYLACETIC ACID HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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3-[3-[N-(2-CHLORO-3-TRIFLUOROMETHYLBENZYL)-(2,2-DIPHENYLETHYL)AMINO]PROPYLOXY]PHENYLACETIC ACID HYDROCHLORIDE Suppliers
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405911-09-3, 3-[3-[N-(2-CHLORO-3-TRIFLUOROMETHYLBENZYL)-(2,2-DIPHENYLETHYL)AMINO]PROPYLOXY]PHENYLACETIC ACID HYDROCHLORIDERelated Search:
3-[3-[n-(2-chloro-3-trifluoromethylbenzyl)-(2,2-diphenylethyl)amino]propyloxy]phenylacetic acid hydrochloride
3-[3-[N-(2-CHLORO-3-TRIFLUOROMETHYLBENZYL)-(2,2-DIPHENYLETHYL)AMINO]PROPYLOXY]PHENYLACETIC ACID HYDROCHLORIDE