3-NITRO-6-PYRIDINECARBOXALDEHYDE

Product Name: 3-NITRO-6-PYRIDINECARBOXALDEHYDE
CAS No.: 35969-75-6
Chemical Name: 3-NITRO-6-PYRIDINECARBOXALDEHYDE
Synonyms: 5-Nitropicolinaldehyde;5-Nitro-2-forMylpyridine;5-nitropyridine-2-carbaldehyde;5-Nitro-2-pyridinecarbaldehyde;5-Nitropyridine-2-carboxaldehyde;5-NITRO-2-PYRIDINECARBOXALDEHYDE;3-NITRO-6-PYRIDINECARBOXALDEHYDE;2-Pyridinecarboxaldehyde, 5-nitro-
CBNumber: CB9221569
Molecular Formula: C6H4N2O3
Formula Weight: 152.11
MOL File: 35969-75-6.mol

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3-NITRO-6-PYRIDINECARBOXALDEHYDE Property

Melting point:: 54-57℃
Boiling point:: 298.7±25.0 °C(Predicted)
Density: 1.432±0.06 g/cm3 (20 ºC 760 Torr)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: -0.31±0.10(Predicted)
Appearance: Brown to reddish brown Solid

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Safety

Risk Statements: 43
Safety Statements: 36/37
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: N519905
Product name: 5-Nitropyridine-2-carbaldehyde
Packaging: 5g
Price: $1175
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H54-1-FP
Product name: 5-Nitropyridine-2-carbaldehyde
Purity: 97.0%
Packaging: 5G
Price: $890
Updated: 2021/12/16

Apolloscientific

Product number: OR921887
Product name: 3-Nitro-6-pyridinecarboxaldehyde
Purity: 95%
Packaging: 5g
Price: $580
Updated: 2021/12/16

ChemScene

Product number: CS-W005150
Product name: 5-Nitropicolinaldehyde
Purity: >97.0%
Packaging: 250mg
Price: $50
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H54-1-FP
Product name: 5-Nitropyridine-2-carbaldehyde
Purity: 97.0%
Packaging: 250mg
Price: $128
Updated: 2021/12/16

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3-NITRO-6-PYRIDINECARBOXALDEHYDE Chemical Properties,Usage,Production

Uses

5-Nitropyridine-2-carbaldehyde is used in the synthetic preparation of pyridine-2-carboxaldehyde thiosemicarbazone which has antitumor activity.

Synthesis

21203-68-9

35969-75-6

The general procedure for the synthesis of 5-nitropyridine-2-carbaldehyde using 2-methyl-5-nitropyridine as starting material was as follows: 2-methyl-5-nitropyridine (3.0 g, 0.021 mol, 1 eq.) was dissolved in 1,4-dioxane (30 mL) at room temperature and selenium dioxide (2.9 g, 0.026 mol, 1.2 eq.) was added with stirring. The reaction mixture was heated to reflux and stirred continuously for 16 hours. Upon completion of the reaction, the mixture was cooled to room temperature and filtered to remove insoluble material. The filtrate was concentrated under reduced pressure and diluted with ethyl acetate (50 mL) and subsequently washed with water (50 mL). The organic phase was dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give 5-nitropyridine-2-carbaldehyde (3.12 g, 94% yield).

References

[1] Patent: WO2013/13815, 2013, A1. Location in patent: Page/Page column 230; 231
[2] Patent: US2013/29962, 2013, A1. Location in patent: Paragraph 1110
[3] Journal of Organic Chemistry, 2012, vol. 77, # 20, p. 8968 - 8979,12
[4] Journal of Medicinal Chemistry, 1992, vol. 35, # 20, p. 3672 - 3677
[5] Patent: WO2005/97752, 2005, A1. Location in patent: Page/Page column 42

3-NITRO-6-PYRIDINECARBOXALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-NITRO-6-PYRIDINECARBOXALDEHYDE Suppliers

China 71 Germany 1 India 2 United Kingdom 1 United States 11 Global 86

Alchem Pharmtech,Inc.

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View Lastest Price from 3-NITRO-6-PYRIDINECARBOXALDEHYDE manufacturers

Shanghai Rlavie Technology Co ltd

Product: 5-nitropyridine-2-carbaldehyde 35969-75-6
Price: US $0.00-0.00/KG
Min. Order: 1g
Purity: 98%min
Supply Ability: 100kgs/month
Release date: 2021-11-21

Career Henan Chemical Co

Product: 3-NITRO-6-PYRIDINECARBOXALDEHYDE 35969-75-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 95-99%
Supply Ability: 1ton
Release date: 2020-01-03

35969-75-6, 3-NITRO-6-PYRIDINECARBOXALDEHYDERelated Search:

3-NITRO-5-PHENYLPYRIDINE 2-Amino-3-nitro-5-trifluoromethylpyridine 2-Methyl-3-nitropyridine-6-carboxylic acid 3-NITRO-6-PYRIDINECARBOXALDEHYDE 3-NITRO-4-PYRIDINECARBOXALDEHYDE 5-Nitropyridine-2-carboxylic acid Methyl 4-amino-5-nitro-2-pyridinecarboxylate Methyl 5-nitro-2-pyridinecarboxylate 4-METHYL-5-NITRO-2-PYRIDINECARBOXYLIC ACID 1-(5-NITROPYRIDIN-2-YL)ETHANONE 2-Pyridinecarboxylicacid,5-nitro-,ethylester(9CI) 2-Methoxy-6-methyl-3-nitro-4-pyridinecarboxaldehyde 2-Methoxy-3-nitro-4-pyridinecarboxaldehyde 6-METHOXY-5-NITROPYRIDINE-2-CARBOXAMIDE 6-CYANO-5-NITROPYRIDINE-2-CARBOXAMIDE 5-nitro-6-methyl-2-pyridinecarbaldehyde CHEMPACIFIC 38214 methyl 5-nitro-6-methyl-2-pyridinecarboxylate

3-NITRO-6-PYRIDINECARBOXALDEHYDE

5-NITRO-2-PYRIDINECARBOXALDEHYDE

5-Nitropyridine-2-carboxaldehyde

5-Nitro-2-forMylpyridine

5-Nitro-2-pyridinecarbaldehyde

5-nitropyridine-2-carbaldehyde

5-Nitropicolinaldehyde

2-Pyridinecarboxaldehyde, 5-nitro-

35969-75-6